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25篇 您的检索式：作者名="Ehrenfeld E"

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	题名	作者	年代	出处	被引量
1	Expression of HER2 and bradykinin B_1 receptors in precursor lesions of gallbladder carcinoma显示文摘AIM:To determine the expression of HER2 and bradykinin B 1 receptors(B 1 R) in the two pathogenic models of gallbladder cancer:the metaplasia-dysplasia-carcinoma and the adenoma-carcinoma pathways.METHODS:Receptor proteins were visualized by immunohistochemistry on 5-μm sections of paraffin-embedded tissue.Expression of both receptors was studied in biopsy samples from 92 patients(6 males and 86 females;age ranging from 28 to 86 years,mean 56 years).High HER2 expression in specimens was additionally investigated by fluorescence in situ hybridiza-tion.Cell proliferation in each sample was assessed by using the Ki-67 proliferation marker.RESULTS:HER2 receptor protein was absent in adenomas and in normal gallbladder epithelium.On the contrary,there was intense staining for HER2 on the basolateral membrane of epithelial cells of intestinal metaplasia(22/24;91.7%) and carcinoma in situ(9/10;90%),the lesions that displayed a significantly high proliferation index.Protein up-regulation of HER2 in the epithelium with metaplasia or carcinoma in situ was not accompanied by HER2 gene amplification.A similar result was observed in invasive carcinomas(0/12).The B 1 R distribution pattern mirrored that of HER2 except that B 1 R was additionally observed in the adenomas.The B 1 R appeared either as cytoplasmic dots or labeling on the apical cell membrane of the cells composing the epithelia with intestinal metaplasia(24/24;100%) and carcinoma in situ(10/10;100%) and in the epithelial cells of adenomas.In contrast,both HER2(4/12;33%) and B 1 R(1/12;8.3%) showed a low expression in invasive gallbladder carcinomas.CONCLUSION:The up-regulation of HER2 and B1R in precursor lesions of gallbladder carcinoma suggests cross-talk between these two receptors that may be of importance in the modulation of cell proliferation in gallbladder carcinogenesis.	Cesar Toledo Carola E Matus Ximena Barraza Pamela Arroyo Pamela Ehrenfeld Carlos D Figueroa Kanti D Bhoola Maeva del Pozo Maria T Poblete	2012	World Journal of Gastroenterology2012，18，11：	6
2	Differential effects of lichens, mosses and grasses on respiration and nitrogen minerali- zation in soils of the New Jersey Pinelands 显示文摘	Sedia E G Ehrenfeld J G	2005	Oecolo- gia2005，144，1：	1
3	U- tility of the surgical apgar score: validation in 4119 patients显示文摘	REGENBOGEN S E EHRENFELD J M LIPSITZ S R	2009	Arch Surg2009，144，1：	1
4	The effects of long-term colchicine therapy on male fertility in patients with familial Mediterranean fever显示文摘	Ehrenfeld M Levy M Margalioth E J	1986	Andrologia1986，18，4：	1
5	Lichens and mosses promote alternate stable plant communities in the New Jersey Pinelands 显示文摘	Sedia E G Ehrenfeld J G	2003	Oikos2003，100，：	1
6	Utility of the surgicalApgar score-validation in 4 119 patients显示文摘	Regenbogen S E Ehrenfeld JM Lipsitz S R		0，，01：	1
7	Immunization against poliomyelitis: moving forward 显示文摘	Ehrenfeld E Glass RI Agol VI	2008	Lancet2008，371，9621：	1
8	Relationship of p220 cleavage during picornavirus infection to 2A protease sequences显示文摘	Lloyd RE Grubman M Ehrenfeld E	1988	J Virol1988，62，：	1
9	Lichens and mosses promote ahemate stable plant communities in the New Jersey Pinelands显示文摘	Sedia E G Ehrenfeld J G	2003	Oikos2003，100，：	1
10	Translation of poliovirus RNA in vitro:changes in cleavage pattern and initiation sites by ribosomal salt wash显示文摘	Brown B A Ehrenfeld E	1979	Virol1979，97，2：	1
11	Immunization against poliomyeli- tis : moving forward显示文摘	Ehrenfeld E Glass RI Agil VI	2008	Lancet2008，，：	1
12	Lichens and mosses promote alternate stable plant communities in the New Jersey Pinelands显示文摘	Sedia E G Ehrenfeld J G	2003	Oikos2003，100，：	1
13	Utility of the surgical Apgar score-validation in 4 119 patients 显示文摘	Regenbogen S E Ehrenfeld J M Lipsitz S R	2009	Arch Surg2009，144，1：	1
14	Identification of pheromone-induced surface proteins in Streptococcus faecalis and evidence of a role for lipoteichoic acid in formation of mating aggregates 显示文摘	EHRENFELD E E KESSLER R E CLEWELL D B	1986	J Bacteriol1986，168，1：	1
15	Strand-specific RNA synthesis defects in a poliovirus with a mutation in protein 3A 显示文摘	Teterina N L Rinaudo M S Ehrenfeld E	2003	J Virol2003，77，12：	1
16	Vaccination against polio should not be stopped显示文摘	Chumakov K Ehrenfeld E Wimmer E	2007	Nat Rev Microbiol2007，5，12：	1
17	Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication显示文摘	Hsu N Y Ilnytska O Belov G Santiana M Chen Y H Takvorian P M Pau C van der Schaar H Kaushik-Basu N Balla T Cameron C E Ehrenfeld E van Kuppeveld FJ Altan-Bonnet N	2010	Cell2010，141，5：	1
18	Viable polioviruses that encode 2A proteins with fluorescent protein tags显示文摘	Teterina NL Levenson EA Ehrenfeld E	2010	J Virol2010，84，：	1
19	Relationship of p220 cleavage during picornavirus infection to 2A proteinase sequencing显示文摘	Lloyd R Grubman M Ehrenfeld E	1988	Virol1988，62，：	1
20	Relationship of eukaryotic initiation factor 3 to poliovirus-indueed p220 cleavage activity显示文摘	Wyckoff E Lloyd R Ehrenfeld E	1992	Virol1992，66，：	1

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