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| 1 | Performance of the Montreal classification for inflammatory bowel diseases显示文摘AIM:To validate the Montreal classification system for Crohn's disease(CD) and ulcerative colitis(UC) within the Netherlands.METHODS:A selection of 20 de-identified medical records with an appropriate representation of the inflammatory bowel disease(IBD) sub phenotypes were scored by 30 observers with different professions(gastroenterologist specialist in IBD,gastroenterologist in training and IBD-nurses) and experience level with IBD patient care.Patients were classified according to the Montreal classification.In addition,participants were asked to score extra-intestinal manifestations(EIM) and disease severity in CD based on their clinical judgment.The inter-observer agreement was calculated by percentages of correct answers(answers identical to the 'expert evaluation') and Fleiss-kappa(k).Kappa cutoffs:< 0.4-poor; 0.41-0.6-moderate; 0.61-0.8-good; > 0.8 excellent.RESULTS:The inter-observer agreement was excellent for diagnosis(k = 0.96),perianal disease(k = 0.92) and disease location in CD(k = 0.82) and good for age of onset(k = 0.67),upper gastrointestinal disease(k = 0.62),disease behaviour in CD(k = 0.79) and disease extent in UC(k = 0.65).Disease severity in UC was scored poor(k = 0.23).The additional items resulted in a good inter-observer agreement for EIM(k = 0.68) and a moderate agreement for disease severity in CD(k = 0.44).Percentages of correct answers over all Montreal items give a good reflection of the inter-observer agreement(> 80%),except for disease severity(48%-74%).IBD-nurses were significantly worse in scoring upper gastrointestinal disease in CD compared to gastroenterologists(P = 0.008) and gastroenterologists in training(P = 0.040).Observers with less than 10 years of experience were significantly better at scoring UC severity than observers with 10-20 years(P = 0.003) and more than 20 years(P = 0.003) of experience with IBD patient care.Observers with 10-20 years of experience with IBD patient care were significantly better at scoring upper gastrointestinal disease in CD than observers with less than 10 years(P = 0.007) and more than 20 years(P = 0.007) of experience with IBD patient care.CONCLUSION:We found a good to excellent interobserver agreement for all Montreal items except for disease severity in UC(poor). | Lieke M Spekhorst Marijn C Visschedijk Rudi Alberts Eleonora A Festen Egbert-Jan van der Wouden Gerard Dijkstra Rinse K Weersma | 2014 | World Journal of Gastroenterology2014，20，41： | 4 |
| 2 | Intramuscular Administration of AAV1-Lipoprotein LipaseS447X Lowers Triglycerides in Lipoprotein Lipase–Deficient Patients显示文摘 | Erik S. Stroes Melchior C. Nierman Janneke J. Meulenberg Remco Franssen Jaap Twisk C Pieter Henny Mario M. Maas Aeilko H. Zwinderman Colin Ross Eleonora Aronica Katherine A. High Marcel M. Levi Michael R. Hayden John J. Kastelein Jan Albert Kuivenhoven | 2008 | Arteriosclerosis Thrombosis and Vascular Biology2008，，12： | 1 |
| 3 | Optimisation of storage allocation in order picking operations through a genetic algorithm显示文摘 | Eleonora B Margherita C Giuseppe V | 2012 | International Journal of Logistics:Research and Applications2012，15，2： | 1 |
| 4 | Approximate theory of linearly polarized light propagation through a scattering medium显示文摘 | Eleonora P Z Ludmila I C | 2000 | Journal of Quantitative Spectroscopy & Radiative Transfer2000，66，： | 1 |
| 5 | A guard-cell-specific MYB transcription factor regulates stomatal movements and plant drought tolerance显示文摘 | Eleonora C Massimo G Alain V | 2005 | Current biology2005，15，： | 1 |
| 6 | Water molecular dynamics during bread staling by Nuclear Magnetic Resonance显示文摘 | Elena C Salvatore B Eleonora C | 2011 | LWT- Food Science and Technology-2011，44，： | 1 |
| 7 | Promotional Effect of Rare Earths and Transition Metals in the Combustion of Diesel Soot over CeO2 and CeO2-ZrO2显示文摘 | Eleonora Aneggi C d L Giuliano Dolcetti Alessandro Trovarelli | 2006 | Catalysis Today2006，111，： | 1 |
| 8 | Removal of As (Ⅲ ) and As ( Ⅴ ) from Water Using a Natural Fe and Mn Enriched Sample显示文摘 | Eleonora D Virginia S T C Wolfgang H H | 2005 | Water Res2005，39，： | 1 |
| 9 | Diagnostic accuracy of fetal renal pelvis anteroposterior diameter as a predictor of significant postnatal nephrouropathy:Second versus third trimester of pregnancy显示文摘 | Dandolo G Stefania F Eleonora C | 2006 | Am J Obstet Gynecol2006，194，： | 1 |
| 10 | Global DNA hypomethylation is an early event in Helicobacter pylori-related gastric carcinogenesis显示文摘 | DEBORA C ALBA R ELEONORA L | | 0，，08： | 1 |
| 11 | Prevalence of-and risk factors for work disability in Dutch patients with inflammatory bowel disease显示文摘AIM To determine the prevalence of work disability in inflammatory bowel disease(IBD), and to assess risk factors associated with work disability.METHODS For this retrospective cohort study, we retrieved clinical data from the Dutch IBD Biobank on July 2014, containing electronic patient records of 3388 IBD patients treated in the eight University Medical Centers in the Netherlands. Prevalence of work disability was assessed in 2794 IBD patients and compared with the general Dutch population. Multivariate analyses were performed for work disability(sick leave, partial and full disability) and long-term full work disability(> 80% work disability for > 2 years).RESULTS Prevalence of work disability was higher in Crohn's disease(CD)(29%) and ulcerative colitis(UC)(19%) patients compared to the general Dutch population(7%). In all IBD patients, female sex, a lower education level, and extra-intestinal manifestations, were associated with work disability. In CD patients, an age > 40 years at diagnosis, disease duration > 15 years,smoking, surgical interventions, and anti-TNFα use were associated with work disability. In UC patients, an age > 55 years, and immunomodulator use were associated with work disability. In CD patients, a lower education level(OR = 1.62, 95%CI: 1.02-2.58), and in UC patients, disease complications(OR = 3.39, 95%CI: 1.09-10.58) were associated with long-term full work disability.CONCLUSION The prevalence of work disability in IBD patients is higher than in the general Dutch population. Early assessment of risk factors for work disability is necessary, as work disability is substantial among IBD patients. | Lieke M Spekhorst Bas Oldenburg Ad A van Bodegraven Dirk J de Jong Floris Imhann Andrea E van der Meulen-de Jong Marieke J Pierik Janneke C van der Woude Gerard Dijkstra Geert D'Haens Mark Lowenberg Rinse K Weersma Eleonora AM Festen 无 | 2017 | World Journal of Gastroenterology2017，23，46： | 1 |
| 12 | Hydrochemical and isotopical evidence of ground water salinization processes on the coastal plain of Samborombon Bay,Argentina显示文摘 | Eleonora C Eduardo K Josep M-P | 2009 | Journal of Hydrology2009，365，34： | 1 |
| 13 | Effect of the addition of bran fractions on bread properties 显示文摘 | Elena C Eleonora C Greta B | 2013 | Journal of Cereal Sci- ence2013，57，： | 1 |
| 14 | Interaction between PPART2 variants and gender on the modulation of body weight显示文摘 | Eleonora M Vittorio T Daria C | 2008 | Obesity2008，16，6： | 1 |
| 15 | Functional and morphological vascular changes in subjects with familial combined hypolipidemia : an exploratory analysis 显示文摘 | ILENIA M VITO C ELEONORA V | 2013 | International Journal of Cardiology2013，168，4： | 1 |
| 16 | Effect of different mixers on physicochemical properties and water status of extruded and laminated fresh pasta显示文摘 | Eleonora C Elena V Elena C | 2010 | Food Chemistry2010，122，： | 1 |
| 17 | Graft dilatation and Barrett’s esophagus in adults after gastric pullup and jejunal interposition for long-gap esophageal atresia显示文摘BACKGROUND Esophageal replacement(ER)with gastric pull-up(GPU)or jejunal interposition(JI)used to be the standard treatment for long-gap esophageal atresia(LGEA).Changes of the ER grafts on a macro-and microscopic level however,are unknown.AIM To evaluate long-term clinical symptoms and anatomical and mucosal changes in adolescents and adults after ER for LGEA.METHODS A cohort study was conducted including all LGEA patients≥16 years who had undergone GPU or JI between 1985-2003 at two tertiary referral centers in the Netherlands.Patients underwent clinical assessment,contrast study and endoscopy with biopsy.Data was collected prospectively.Group differences between JI and GPU patients,and associations between different outcome measures were assessed using the Fisher’s exact test for bivariate variables and the Mann-Whitney U-test for continuous variables.Differences with a P-value<0.05 were considered statistically significant.RESULTS Nine GPU patients and eleven JI patients were included.Median age at follow-up was 21.5 years and 24.4 years,respectively.Reflux was reported in six GPU patients(67%)vs four JI patients(36%)(P=0.37).Dysphagia symptoms were reported in 64%of JI patients,compared to 22%of GPU patients(P=0.09).Contrast studies showed dilatation of the jejunal graft in six patients(55%)and graft lengthening in four of these six patients.Endoscopy revealed columnar-lined esophagus in three GPU patients(33%)and intestinal metaplasia was histologically confirmed in two patients(22%).No association was found between reflux symptoms and macroscopic anomalies or intestinal metaplasia.Three GPU patients(33%)experienced severe feeding problems vs none in the JI group.The median body mass index of JI patients was 20.9 kg/m^(2) vs 19.5 kg/m^(2) in GPU patients(P=0.08).CONCLUSION The majority of GPU patients had reflux and intestinal metaplasia in 22%.The majority of JI patients had dysphagia and a dilated graft.Follow-up after ER for LGEA is essential. | Eleonora Sofie van Tuyll van Serooskerken Gabriele Gallo Bas L Weusten Jessie Westerhof Lodewijk AA Brosens Sander Zwaveling Jetske Ruiterkamp Jan BF Hulscher Hubertus GM Arets Arnold JN Bittermann David C van der Zee Stefaan HAJ Tytgat Maud YA Lindeboom | 2023 | World Journal of Gastrointestinal Endoscopy2023，15，9： | 0 |
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