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| 1 | Liver stiffness as a predictor of hepatocellular carcinoma behavior in patients with hepatitis C related liver cirrhosis显示文摘Background: Risk strati cation and prognostication of hepatocellular carcinoma (HCC) help to improve patient outcome. Herein we investigated the role of liver stiffness measurement (LSM) in the prediction of HCC behavior. Methods: Totally 121 na ve patients with HCC were included. HCC radiological evaluation and staging were done. LSM was measured using virtual touch quanti cation. Patients were divided into early to intermediate HCC (BCLC-0, A and B) and late HCC (BCLCC and D). HCC was treated according to the BCLC stage. HCC recurrence-free interval was estimated. Results: The mean LSM inside the tumor was signi cantly lower than the peri-tumoral area and the cirrhotic non-cancerous liver parts (P<0.001). In late HCCs stage, the mean LSM inside the tumor and in the peri-tumoral tissue was lower than the corresponding values in the early to intermediate HCCs stage (P<0.001). LSM inside the tumor and in the peri-tumoral tissue negatively correlated with serum AFP, tumor vascular invasion, and stage (P<0.05). The recurrence-free interval was directly correlated to LSM inside the tumor and inversely to LSM in cirrhotic non tumorous liver part. Kaplan-Meier analysis showed that the recurrence-free interval was signi cantly longer in patients with LSM inside the tumor of ≥1.25m/s compared to those with LSM inside the tumor of<1.25m/s. Conclusions: LSM can serve as a potential non-invasive predictor for HCC clinical behavior and the recurrence-free interval following loco-regional treatments. | Sameh A Lashen Mohamed M Elshafei Fahmy H Hablass Eman A Alsayed Asmaa A Hassan | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，1： | 4 |
| 2 | 榆树皮化学成分研究显示文摘目的:研究榆树皮的化学成分。方法:采用硅胶柱色谱和Sephadex LH-20凝胶柱色谱等方法进行分离纯化。通过所得单体化合物的理化性质和波谱分析(1H-NMR与13C-NMR)以及相关文献的佐证鉴定化合物结构。结果:从榆树皮中分离得到了11个化合物,分别鉴定为:β-胡萝卜苷(1)、methyl-α-D-apiofuranoside(2)、东莨菪苷(3)、nudiposide(4)、(+)-5′-methoxyisolariciresinol-9-O-β-D-xylopyranoside(5)、尿嘧啶核苷(6)、icariside E3(7)、4,5-甲氧基-3-羟基-1-苯酚-β-D-葡萄糖苷(8)、红景天苷(9)、icariside E4(10)、紫花松果菊苷A(11)。结论:其中,化合物2、3、5~11为首次从该植物中分离得到,化合物2、3、6、8、9、11为首次从该属植物中分离得到。 | 程盛宇 Alaa Elshafei 于跃 李娜 郑明善 | 2020 | 中药材2020，43，4： | 4 |
| 3 | 榆白皮的化学成分和药理活性研究进展显示文摘榆白皮是榆科(Ulmaceae)植物榆(Ulmus pumila L.)的树皮和根皮的韧皮部部分,广泛分布于全国各省区,资源非常丰富。主要含有萜类、苯丙素、木质素和黄酮类等多种化学成分,并具有抗炎、抗氧化、抗菌、抗败血症等多种药理活性,尤其是在抗肿瘤方面,更具潜在的研究价值。本文全面查阅并总结近30年来的国内外文献,对榆白皮的化学成分和药理活性进行归纳总结,以期为该药材更深入的研究与开发提供参考。 | 李娜 程盛宇 应韬 Alaa Elshafei 于跃 郑明善 | 2018 | 国际药学研究杂志2018，0，12： | 4 |
| 4 | Environmentally friendly pesticides: Essential oil-basedw/o/w multiple emulsions for anti-fungal formulations显示文摘 | Elshafei G M S El-Said M M Attia H A E | 2010 | Industrial Crops Products2010，31，1： | 1 |
| 5 | Finite Element Model of Smart Beams with Distributed'Piezoelectric Actuators显示文摘 | Bendary I M Elshafei M A Riad A M | 2010 | Journal of Intelligent Material Systems and Structures2010，，3： | 1 |
| 6 | PCA3-based nomogram for predicting prostate cancer and high grade cancer on initial transrectal guided biopsy显示文摘 | Elshafei A Chevli KK Moussa AS | 2015 | Prostate2015，75，16： | 1 |
| 7 | Neoadjuvant chemotherapyversusprimary surgery in advanced ovarian car- cinoma显示文摘 | Hegazy MA Hegazi RA Elshafei MA | 2005 | World J Surg Oncol2005，3，1： | 1 |
| 8 | Role of quantitative diffusion-weighted MRI and 'H MR spectroscopy in distinguishing betweenbenign and malignant thyroid nodules显示文摘 | Elshafey R Elattar A Mlees M | 2014 | Egypt J Radiol Nucl Med2014，45，： | 1 |
| 9 | Colonic conduit for esophageal replacement:long-term endoscopic and histopatholo-gic changes in colonic mucosa显示文摘 | Elshafei H Elshafei E ELdebeiky M | 2012 | Pediatr Surg2012，47，6： | 1 |
| 10 | Neoadjuvant chemothera- py versus primary surgery in advanced ovarian carcinoma显示文摘 | Hegazy MA Hegazl RA Elshafei MA | 2005 | World J Surg Oneo12005，31，3： | 1 |
| 11 | Production of single cell protein from yeast strains grown in Egyptian vinasse 显示文摘 | Selim M H Elshafei A M El-Diwany A I | 1991 | Bioresource Technology1991，36，2： | 1 |
| 12 | Adaptive antenna shape control using piezoelectric actuators显示文摘 | BRIJ N Agrawal M Adnan Elshafei Gangbing Song | 1997 | Acta Astronautica1997，40，11： | 1 |
| 13 | Robust longitudinal aircraft control based on an adaptive fuzzy logic Algorithm显示文摘 | Elshafei A L | 2003 | Con- trol and intelligent systems2003，31，2： | 1 |
| 14 | Neoadjuvant chemotherapy versus primary surgery in advanced ovarian carcinoma显示文摘 | Hegazy MA Hegazi RA Elshafei MA | 2005 | World J Surg Oncol2005，3，1： | 1 |
| 15 | Adaptive antenna shape control using piezoelectric actuators 显示文摘 | Agrawal B M Elshafei G Song | 1997 | Acta Astronautica1997，40，11： | 1 |
| 16 | Parametric models for helicopter identification using ANN 显示文摘 | Elshafei M Akhtar S Ahmed M S | 2000 | IEEE Transactions on Aerospace and Electronic Systems2000，36，： | 1 |
| 17 | Neoadjuvant chemotherapy versus primary surgery in advanced ovarian carcinoma显示文摘 | Hegazy MA Hegazi RA Elshafei MA | | 0，，01： | 1 |
| 18 | Salvage focal prostate cryoablation for locally recurrent prostate cancer after radiotherapy: initial results from the cryo on-line data registry 显示文摘 | LI Y H ELSHAFEI A AGARWALG | 2015 | Prostate2015，75，1： | 1 |
| 19 | Neoadjuvant chemotherapy versus primary surgery in advanced ovarian carcinoma 显示文摘 | Hegazy MA Hegazi RA Elshafei MA | 2005 | World Journal of Surgical Oncology2005，3，1： | 1 |
| 20 | Damping inter- area modes of oscillation using an adaptive fuzzy power system stabilizer显示文摘 | HUSSEIN T SAAD M S ELSHAFEI A L | 2010 | Electric Power Systems Research2010，80，12： | 1 |
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