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您的检索式：作者名="Emmanuel Oger"
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| 1 | Major gastrointestinal bleeding and antithrombotics: Characteristics and management显示文摘BACKGROUND There are few reports on major gastrointestinal(GI)bleeding among patients receiving an antithrombotic.AIM To describe clinical characteristics,bleeding locations,management and inhospital mortality related to these events.METHODS Over a three-year period,we prospectively identified 1080 consecutive adult patients admitted in two tertiary care hospitals between January 1,2013 and December 31,2015 for major GI bleeding while receiving an antithrombotic.The bleeding events were medically validated.Clinical characteristics,causative lesions,management and fatalities were described.The distribution of antithrombotics prescribed was compared across the bleeding lesions identified.RESULTS Of 576 patients had symptoms of upper GI bleeding and 504 symptoms of lower GI bleeding.No cause was identified for 383(35.5%)patients.Gastro-duodenal ulcer was the first causative lesion in the upper tract(209 out of 408)and colonic diverticulum the first causative lesion in the lower tract(120 out of 289).There was a larger proportion of direct oral anticoagulant use among patients with lower GI than among those with upper GI lesion locations(P=0.03).There was an independent association between gastro-duodenal ulcer and antithrombotic use(P=0.03),taking account of confounders and proton pump inhibitor coprescription.Pair wise comparisons pointed to a difference between vitamin K antagonist,direct oral anticoagulants,and antiplatelet agents in monotherapy vs dual antiplatelet agents.CONCLUSION We showed a higher rate of bleeding lesion identification and suggested a different pattern of antithrombotic exposure between upper and lower GI lesion locations and between gastro-duodenal ulcer and other identified upper GI causes of bleeding.Management was similar across antithrombotics and in-hospital mortality was low(5.95%). | Jacques Bouget Damien Viglino Quentin Yvetot Emmanuel Oger | 2020 | World Journal of Gastroenterology2020，26，36： | 1 |
| 2 | Impact of rotavirus vaccination on hospitalizations for rotavirus diarrhea: The IVANHOE study显示文摘 | Arnaud Gagneur Emmanuel Nowak Thomas Lemaitre Jean-Francois Segura Nadège Delaperrière Lydie Abalea Elise Poulhazan Anne Jossens Lucie Auzanneau Adissa Tran Christopher Payan Nadine Jay Loic de Parscau Emmanuel Oger | 2011 | Vaccine2011，，21： | 1 |
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