2篇
您的检索式：作者名="Engin Akman"
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| 1 | Imatinib response of gastrointestinal stromal tumor patients with germline mutation on KIT exon 13:A family report显示文摘Familial gastrointestinal stromal tumor(GIST) is a rare autosomal dominant disorder associated with mutations in the KIT gene in the majority of cases. Although, exon 11 appears to be the hot spot region for approximately 95% of germline mutations, pathogenic variations have also been identified in exon 8, 13 and 17. Exon 13 germline mutations are extremely rare amongst familial GISTs and seven families with a germline mutation have been reported to date. Moreover, the role of imatinib mesylate in this rare familiar settings is not completely known so far. We describe here clinical, imaging, pathological and genetic findings of a family with four affected members; grandmother, his son and two grand-sons having a germline gain-of-function mutation of KIT in exon 13 and discuss the imatinib mesylate treatment surveillance outcomes towards disease management. | Gulgun Engin Serpil Eraslan Hülya Kayserili Yersu Kapran Haluk Akman Ali Akyuz Nuri Faruk Aykan | 2017 | World Journal of Radiology2017，9，9： | 3 |
| 2 | Visa trial of international trade:evidence from support vector machines and neural networks显示文摘International trade depends on networking,interaction and in-person meetings which stimulate cross-border travels.The countries are seeking policies to encourage inbound mobility to support bilateral trade,tourism,and foreign direct investments.Some nations have been implementing liberal visa regimes as an important part of facilitating policies in view of security concerns.Turkey has been among the nations introducing liberal visa policies to support trade in the last decade and recorded significant increases in the volumes of exports.In this paper,we employed machine learning methodologies,Support vector machines(SVM)and Neural networks(NN),to investigate the facilitating impact of liberal visa policies on bilateral trade,using the export data from Turkey for the period of 2000–2014.The research disentangled the variables that have the strongest impact on trade utilizing SVM and NN models and exhibited that visa policies have significant impacts on the bilateral trade.More relaxed visa policies are recommended for the countries in the pursuit of increasing exports. | Engin Akman Abdullah S.Karaman Cemil Kuzey | 2020 | Journal of Management Analytics2020，7，2： | 2 |
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