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| 1 | Using old liver grafts for liver transplantation: Where are the limits?显示文摘The scarcity of ideal liver grafts for orthotopic liver transplantation(OLT) has led transplant teams to investigate other sources of grafts in order to augment the donor liver pool. One way to get more liver grafts is to use marginal donors, a not well-defined group which includes mainly donors > 60 years, donors with hypernatremia or macrosteatosis > 30%, donors with hepatitis C virus or hepatitis B virus positive serologies, cold ischemia time > 12 h, non-heart-beating donors, and grafts from split-livers or living-related donations. Perhaps the most practical and frequent measure to increase the liver pool, and thus to reduce waiting list mortality, is to use older livers. In the past years the results of OLT with old livers have improved, mainly due to better selection and maintenance of donors, improvements in surgical techniques in donors and recipients, and intra- and post-OLT management. At the present time, sexagenarian livers are generally accepted, but there still exists some controversy regarding the use of septuagenarian and octogenarian liver grafts. The aim of this paper is to briefly review the aging process of the liver and reported experiences using old livers for OLT. Fundamentally, the series of septuagenarian and octogenarian livers will be addressed to see if there is a limit to using these aged grafts. | Carlos Jiménez-Romero Oscar Caso Maestro Félix Cambra Molero Iago Justo Alonso Cristina Alegre Torrado Alejandro Manrique Municio Jorge Calvo Pulido Carmelo Loinaz Segurola Enrique Moreno González | 2014 | World Journal of Gastroenterology2014，20，31： | 11 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Infectious, atopic and inflammatory diseases, childhood adversities and familial aggregation are independently associated with the risk for mental disorders: Results from a large Swiss epidemiological study显示文摘AIM To examine the associations between mental disorders and infectious, atopic, inflammatory diseases while adjusting for other risk factors.METHODS We used data from PsyC oL aus, a large Swiss Population Cohort Study(n = 3720; age range 35-66). Lifetime diagnoses of mental disorders were grouped into the following categories: Neurodevelopmental, anxiety(early and late onset), mood and substance disorders. They were regressed on infectious, atopic and other inflammatory diseases adjusting for sex, educational level, familial aggregation, childhood adversities and traumatic experiences in childhood. A multivariate logistic regression was applied to each group of disorders. In a complementary analysis interactions with sex were introduced via nested effects. RESULTS Associations with infectious, atopic and other chronic inflammatory diseases were observable together with consistent effects of childhood adversities and familial aggregation, and less consistent effects of trauma in each group of mental disorders. Streptococcal infections were associated with neurodevelopmental disorders(men), and measles/mumps/rubella-infections with early and late anxiety disorders(women). Gastric inflammatory diseases took effect in mood disorders(both sexes) and in early disorders(men). Similarly, irritable bowel syndrome was prominent in a sex-specific way in mood disorders in women, and, moreover, was associated with early and late anxiety disorders. Atopic diseases were associated with late anxiety disorders. Acne(associations with mood disorders in men) and psoriasis(associations with early anxiety disorders in men and mood disorders in women) contributed sex-specific results. Urinary tract infections were associated with mood disorders and, in addition, in a sex-specific way with late anxiety disorders(men), and neurodevelopmental and early anxiety disorders(women).CONCLUSION Infectious, atopic and inflammatory diseases areimportant risk factors for all groups of mental disorders. The sexual dimorphism of the associations is pronounced. | Vladeta Ajdacic-Gross Aleksandra Aleksandrowicz Stephanie Rodgers Margot Mutsch Anja Tesic Mario Müller Wolfram Kawohl Wulf R?ssler Erich Seifritz Enrique Castelao Marie-Pierre F Strippoli Caroline Vandeleur Roland von K?nel Rosa Paolicelli Markus A Landolt Cornelia Witthauer Roselind Lieb Martin Preisig | 2016 | World Journal of Psychiatry2016，6，4： | 2 |
| 4 | Organic and inorganiccarbon in soils of semiarid regions : A case study from the Guadix-Baza ba-sin ( Southeast Spain) 显示文摘 | JOSE L DIAZ-HERNANDEZ A ENRIQUE B F | 2003 | Geoderma2003，114，： | 1 |
| 5 | Multicenter, randomized, double-blind, placebo-controlled study on the effect of oral tolvaptan on left ventricular dilation and function in patients with heart failure and systolic dysfunction显示文摘 | JAMES U FRABK A ENRIQUE F | 2008 | J Am Coll Cardiol2008，49，22： | 1 |
| 6 | Towards personalized recommendation by two-step modified apriori data mining algo- rithm 显示文摘 | Enrique L Federico B Antonio F C | 2008 | Expert System with Application2008，35，3： | 1 |
| 7 | Sublingual immunotherapy for hazelnut food allergy : a follow-up study 显示文摘 | Enrique E Malek T Pineda F | 2008 | Ann Allergy Asthma hnmuno12008，100，3： | 1 |
| 8 | Chronic balance disor- ders after acoustic neuroma surgery:assessment of gravita- tional vertical perception 显示文摘 | Hamlet S Enrique F Sofia A | 2015 | Acta oto - laryngologica2015，135，4： | 1 |
| 9 | An approachfor determining air pollution monitoring sites 显示文摘 | Enrique G F MaMa D M Isabel M M T | 2010 | Atmospheric1 Environment2010，44，2122： | 1 |
| 10 | Consequence a- nalysis by means of characteristic curves to determine the damage to humans from the detonation of explosive substances as a function of TNT equivalence显示文摘 | Fernando D A Enrique G F Marta D M | 2008 | Journal of Loss Prevention in the Process Industries2008，20，1： | 1 |
| 11 | Immediate application of positive-end expiratory pressure is more effective than delayed positive-end expiratory pressure to reduce extravascular lung water 显示文摘 | Manuel R Enrique F Benjamin H | 1999 | Cri Care Med1999，27，2： | 1 |
| 12 | Generation of banded iron formations by internal dynamics and leaching of oceanic crest显示文摘 | Wang Y F Xu H F Enrique M | 2009 | Nature Genscience2009，2，11： | 1 |
| 13 | Domain-selective reactivity of hydroquinone-derived adlayers at basal pt (hkl) single-crystal electrodes 显示文摘 | MARGARITA R L ANTONIO R ENRIQUE H PAULINO T JUAN M F ANTONIO A AMALDO C J | 2009 | Langmuir2009，25，10： | 1 |
| 14 | A consensus model for muhiperson decision making with different preference structures显示文摘 | Enrique H V Herrera F Chiclana F | 2002 | IEEE Trans on Systems Man and Cybernetics - Part A : Systems and Humans2002，32，3： | 1 |
| 15 | Species richness and distribution of copepods and cladocerans and their relation to hydroperiod and other environmental variables in Donana, south- west Spain显示文摘 | DAGMAR F ENRIQUE M O GREEN A J | 2006 | Hydrobiologia2006，556，： | 1 |
| 16 | Towards an integrated crowd- sourcing definition显示文摘 | AROLAS E ENRIQUE GUEVARA F | 2012 | Journal of Information Science2012，，38： | 1 |
| 17 | Improving efficiency and reliability in water distribution systems显示文摘 | | 1994 | Kluwer Academic Publishers1994，，： | 1 |
| 18 | Down-regulation of DR12, an auxin-response-factor homolog,in the tomato results in a pleiotropic phenotype including dark green and blotchy ripeningfruit显示文摘 | BRIAN J PIERRE F ENRIQUE O | 2002 | The Plant Journal2002，32，： | 1 |
| 19 | Cholecalciferol modulates plasma phosphate but not plasma vitamin D levels and intesti- nal phosphate absorption in rainbow trout (Oncorhyrwhus mykiss ) 显示文摘 | Enrique M A Sandra P B Ronaldo P F | 1999 | Gen Comp EndocrinoI1999，114，： | 1 |
| 20 | Graft union formation in tomato plants:peroxidase and catalase involve ment显示文摘 | Nieves F G Micaela C Enrique O | | 0，，01： | 1 |
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