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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | Blueberry hybrids with complex genetic backgrounds evaluated on mineral soils:cold hardiness as influenced by parental species and location显示文摘 | Hancock J F Goulart B L Erd W A | 1997 | Acta Horticulturae1997，446，： | 1 |
| 3 | Regulatory T Cell, a potent immunoregulatory target for CAM researchers: modulating tumor immunity, autoimmunity and aUoreactive immunity (Ⅲ)显示文摘 | Vojdani A Erde J | 2006 | Evid Based Complement Altemat Med2006，3，3： | 1 |
| 4 | Production of a mouse monoelonal antibody reactive with a human nuclear antigen associated with cell proliferation显示文摘 | erdes J Schwab U Lemke H | 1983 | Int J Cancer1983，31，1： | 1 |
| 5 | Development and application of triglyceride-based polymer and eomposites显示文摘 | Shrikant N K John J L Erde C | 2001 | J Applid Polymer Sci2001，82，： | 1 |
| 6 | Corneal topography changes after a 15s seconds pouse in blinking显示文摘 | N é meth J Erd é lyi B Cs á k á ny B | 2001 | Cataract Reftact Surg2001，27，： | 1 |
| 7 | Investigations into the impact of the template layer on ZnO nanowire arrays made using low temperature wet chemical growth显示文摘 | Erdeélyi R Nagata T Rogers D J | 2011 | Cryst Growth Des2011，11，6： | 1 |
| 8 | Reproducibility of keratometric measurements decreases with time after blinking显示文摘 | Erd é lyi B Cs á k á ny B N é meth J | 2006 | Eur J Ophthalmol2006，16，3： | 1 |
| 9 | High-speed videotopographic measurement of tear film build-up time显示文摘 | N é meth J Erd é lyi B Cs á k á ny B | 2002 | Invest Ophthalmol Vis Sci2002，43，： | 1 |
| 10 | A new role for Nogo as a regulator of vascular remodeling显示文摘 | Acevedo L Yu J Erd]ument-Bromage H | 2004 | Nat Med2004，10，4： | 1 |
| 11 | Planned and ongoing projects ( POP ) database : development and results 显示文摘 | Wild C Erds J Warmuth M | 2014 | International Journal of Technology Assessment in Health Care2014，30，5： | 1 |
| 12 | Manipulation of the immune response to a plasmidencoded viral antigen by coinoculation with plasmids expressing cytokines 显示文摘 | Xiang Z Q Erd H C J | 1995 | Immunity1995，2，： | 1 |
| 13 | Buddingtonite, an ammonium feldsparwith zeolitic water 显示文摘 | Erd R C White D E Fahey J J | 1964 | American Mineralogist1964，49，： | 1 |
| 14 | The expression of the Hedgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue : evidence that Reed-Steinberg cells and histioeytic malignancies are derived from activated lymphoid cells显示文摘 | Stein H Mason DY C erdes J | 1985 | Blood1985，66，4： | 1 |
| 15 | Deanesmithite Hg2Hg3CrO5S2, a new mineral species from the Clear Creek Claim, San Benito County, California显示文摘 | ROBERTS A C SZYMANSKI J T ERD R C | 1993 | The Canadian Mineralogist1993，31，4： | 1 |
| 16 | Myosin light chain phosphatase:subunit composition,interactions and regulation显示文摘 | HARTSHORNE D J ITO M ERD?DI F | 1998 | J Mus Res Cell Motil1998，19，： | 1 |
| 17 | Manipulation of the immune response to a plasmid encoded virul atigen by coinocultion with plasmids exp ressing cytokines显示文摘 | Xiang Z Q Erd H C J | 1995 | Immuntiy1995，，2： | 1 |
| 18 | High-speed videotopographic measurement of tear film build-up time显示文摘 | Németh J Erdélyi B Csákány B | 2002 | Invest Ophthalmol Vis Sci2002，43，6： | 1 |
| 19 | Role of protein phosphatase type 1 in contractile functions:myosin phosphatase显示文摘 | Hartshorne D J Ito M Erd?di F | 2004 | J Biol Chem2004，279，37： | 1 |
| 20 | Improved islet isolation from rat pancreas using35%bovine serum albumin in combination with dextran gradient separation显示文摘 | Field J Farney A Sutherland ERD | 1996 | Transplantation1996，61，10： | 1 |
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