|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Adrenomedullin in cirrhotic and non-cirrhotic portal hypertension显示文摘AIM:Adrenomedullin (ADM) is a potent vasodilator peptide.ADM and nitric oxide (NO) are produced in vascular endothelial cells. Increased ADM level has been linked to hyperdynamic circulation and arterial vasodilatation in cirrhotic portal hypertension (CPH). The role of ADM in non-cirrhotic portal hypertension (NCPH) is unknown, plasma ADM levels were studied in patients with NCPH, compensated and decompensated cirrhosis in order to determine its contribution to portal hypertension (PH) in these groups.METHODS: There were 4 groups of subjects. Group 1consisted of 27 patients (F/M: 12/15) with NCPH due to portal and/or splenic vein thrombosis (mean age: 41±12years), group 2 consisted of 14 patients (F/M: 6/8) with compensated (Child-Pugh A) cirrhosis (mean age: 46±4),group 3 consisted of 16 patients (F/M: 6/10) with decompensated (Child-Pugh C) cirrhosis (mean age: 47±12).Fourteen healthy subjects (F/M: 6/8) (mean age: 44±8) were used as controls in Group 4. ADM level was measured by ELISA. NO was determined as nitrite/nitrate level by chemoluminescence.RESULTS: Adl level in Group 11 (236±61.4 pg/mL) was significantly higher than that in group 2 (108.4±28.3 pg/mL)and group 4 (84.1±31.5 pg/mL) (both P<0.0001) but was lower than that in Group3 (324±93.7 pg/mL) (P=0.002). NO level in group 1 (27±1.4 μmol/L) was significantly higher than that in group 2 (19.8±2.8 μmol/L) and group 4 (16.9±1.6μmol/L) but was lower than that in Group 3 (39±3.6 μmol/L)(for all three P<0.0001). A strong correlation was observed between ADM and NO levels (r=0.827, P<0.0001).CONCLUSION: Adrenomedullin and NO levels were high in both non-cirrhotic and cirrhotic portal hypertension and were closely correlated, Adrenomedullin and NO levels increased proportionally with the severity of cirrhosis, and were significantly higher than those in patients with NCPH.Portal hypertension plays an important role in the increase of ADM and NO. Parenchymal damage in cirrhosis may contribute to the increase in these parameters. | V Tahan E Avsar C Karaca E Uslu F Eren S Aydin H Uzun HO Hamzaoglu F Besisik C Kalayci A Okten N Tozun | 2003 | World Journal of Gastroenterology2003，9，10： | 5 |
| 2 | Vascular injuries and amputation following limb fractures 显示文摘 | EREN N OZGEN G GUREL A | 1990 | Thorac Cardiovasc Surg1990，38，： | 1 |
| 3 | The determinants of right ventricular function in patients with atrial septal defect显示文摘 | Gorgulu S Eren M Uslu N | 2006 | Int J Cardiol2006，111，： | 1 |
| 4 | Sudden death related to anomalous origin of coronary artery and coexisting fenestrated membrane of the sinus coronaries显示文摘 | Türkmen N Eren B Fedakar R | 2007 | Singapore Med J2007，48，7： | 1 |
| 5 | Biochemical markers of bone turnover and bone mineral density in patients with beta-thalassaemia major显示文摘 | Eren E Yilmaz N | | 0，，01： | 1 |
| 6 | Diagnostic value of C -reactive protein in patients with angiographically documentedcoronary heart disease 显示文摘 | Eren E Yilmaz N Pence S | 2002 | Aeta Medic(Hradec Kralove)2002，45，4： | 1 |
| 7 | Lower extremity arterial injuries over a six-year period: outcomes, risk factors, and management显示文摘 | Askin Ender Topal Y Celik N Eren | 2010 | Vascular Health and Risk Management (default)2010，，： | 1 |
| 8 | Clinical efficacy of Saccharomyces boulardii or metronidazole in symptomatic children with Blastocystis hominis infection 显示文摘 | Dinleyici EC Eren M Dogan N | 2011 | Parasitol Res2011，108，3： | 1 |
| 9 | Removal of Cu ( Ⅱ ) ions by activated poplar sawdust ( Samsun Clone) from aqueous solutions 显示文摘 | Acar F N Eren Z | 2006 | Journal of Hazardous Materials2006，137，： | 1 |
| 10 | Quantum-chemical, IR, NMR, and X-ray diffraction studies on 2-( 4-chloro?phenyl)-l-methyl-lH-benzo显示文摘 | Ozdemir N Eren B Dincer M | 2011 | IntJ Quantum Chem2011，111，12： | 1 |
| 11 | Oxidative stress and ischemi- a-modified albumin in chronic ischemic heart failure 显示文摘 | Ellidag HY Eren E Yilmaz N | 2014 | Redox Rep2014，19，3： | 1 |
| 12 | Diagnostic value of C-reactive protein in patients with angiographically documented coronary heart disease显示文摘 | Yilmaz N Pence S | 2002 | Acta Medica (Hradec Kralove)2002，45，4： | 1 |
| 13 | Effects of N-acetylcysteine on pul- monary function in patients undergoing coronary artery bypass surgery with cardiopulmonary bypass显示文摘 | Eren N Cakir O Oruc A | 2003 | Perfusion2003，18，6： | 1 |
| 14 | 直接前方入路全髋置换术的临床应用趋势显示文摘为研究直接前方入路(DAA)全髋置换术的临床应用趋势,作者进行了一项电子邮件调查,对象是美国髋膝关节协会会员医生,分析DAA全髋置换术的临床预期效果和经济效益。996位医生给予了回复,占美国髋膝关节协会会员医生44.3%,其中56.2%的医生做DAA全髋置换术。做DAA全髋置换术医生比不做DAA全髋置换术医生执业年限短(分别为17年和20.9年);同样,做DAA全髋置换术比较多的医生比做DAA全髋置换术少的医生执业年限短。做DAA全髋置换术的医生认为翻修术、解剖复杂以及身体状况是改行后路全髋置换术的常见原因。不做DAA全髋置换术医生认为DAA全髋置换效果不佳、无临床益处以及学习曲线长。 | Patel N N Shah J A Erens G A 胡孔足 | 2019 | 临床骨科杂志2019，22，3： | 1 |
| 15 | Clinical evaluation(Phase I)of a human monoclonal antibody against hepatitis Cvirus:Safety and antiviral activity显示文摘 | Galun E Terrault N A Eren R | 2007 | J Hepatol2007，46，： | 1 |
| 16 | Surgical Treatment of Post-Traumatic Tracheobronchial Injuries: 14-year experience 显示文摘 | Balci AE Eren N Eren S | 2002 | European Journal of Cardiothoracic Surgery2002，22，6： | 1 |
| 17 | Diagnostic value of C-reactive protein in patients with angiographically documented coronary heart disease 显示文摘 | Eren E Yilmaz N Pence S | 2002 | Acta Medica ( Hradec kralove)2002，，4： | 1 |
| 18 | Diagnostic value of C-reactive protein in patients with angiographically documented coronary heart disease显示文摘 | Eren E Yilmaz N Pence S et a | 2002 | Acta Medica( Hradec kralove )2002，，4： | 1 |
| 19 | Diag- nostic value of C-reactive protein in pati- ents with angiographically documented coronary heart disease显示文摘 | Eren E Yilmaz N Pence S | 2002 | Acta Medic (Hradec Kralove)2002，45，4： | 1 |
| 20 | Facile and green fabrication of silver nanoparticles on a polyoxometalate for Li-ion battery显示文摘 | EREN T ATAR N YOLA M L | 2015 | Ionics2015，9，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员