|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming显示文摘新陈代谢对房间功能的每个方面重要,然而,导致的 pluripotent 干细胞(iPSCs ) 的 metabolome 仍然保持大部分未经勘探。这里,我们报导,用一条 untargeted metabolomics 途径,那人的 iPSCs 份额有从他们的父母房间是不同的胚胎的干细胞(转换字符) 的 pluripotent metabolomic 签名,并且那被变化在涉及细胞的呼吸的代谢物描绘。细胞的 bioenergetics 的检查与我们的 metabolomic 分析支持了,并且证明体的房间在 pluripotency 从一个氧化状态变换成一个 glycolytic 状态。有趣地,各种各样的体的房间的 bioenergetics 与他们的 reprogramming 效率相关。我们进一步识别了在 iPSCs 和转换字符之间不同的代谢物,它揭示了在调整体的房间 reprogramming 起一个关键作用的新奇新陈代谢的小径。我们的调查结果是第一全球性分析 iPSCs 的 metabolome,并且提供机械学的卓见进涉及导致 pluripotency,并且在评估 iPSC 和转换字符等价的规定的新层。 | Athanasia D Panopoulos Oscar Yanes Sergio Ruiz Yasuyuki S Kida Dinh Diep Ralf Tautenhahn Aida Herrerias Erika M Batchelder Nongluk Plongthongkum Margaret Lutz W Travis Berggren Kun Zhang Ronald M Evans Gary Siuzdak Juan Carlos Izpisua Belmonte] | 2012 | Cell Research2012，22，1： | 12 |
| 2 | Application of Line Geometry and Linear Complex Approximation to Singularity Analysis of the 3-DOF CaPaMan Parallel Manipulator 显示文摘 | W Alon O Erika S Moshe | 2004 | Mechanism and Machine Theory2004，39，1： | 1 |
| 3 | Fabrication of High-Aspect-Ratio Prussian Blue Nanotubes Using a Porous Alumina Template显示文摘 | Anders J Erika W Lu Jun | 2005 | Nano Letters2005，5，8： | 1 |
| 4 | PI3K/AKT pathway alterations are associated with clinically aggressive and histologically anaplastic subsets of pilocytic astrocytoma显示文摘 | Erika F Rodriguez Bernd W | 2010 | Acta Neuropathologica2010，121，3： | 1 |
| 5 | Potential of salix as phytoextractor for Cd on moderately contaminated soils显示文摘 | Jan E | 2003 | Plant and soil2003，249，1： | 1 |
| 6 | Expression of alpha v beta 3 integrin in patients with high and low grade glioma显示文摘 | Oliver S Bjarne K Erika W | 2006 | Proc Am Assoc Cancer Res2006，47，8： | 1 |
| 7 | Protocol: a highly sen- sitive RT-PCR method for detection and quantification of mi- croRNAs显示文摘 | Erika V G Rong M W Marion W | 2007 | Plant Methods2007，，3： | 1 |
| 8 | Hepcidin,a urinary antimierobial peptide synthesized in the liver显示文摘 | CHRISTINA H P ERIKA V V ALAN J W | 2001 | Biologieal Chemistry2001，276，11： | 1 |
| 9 | Anti-Ids in Allergy : timeliness of a classic concept显示文摘 | JULIA W ISABELLA P S ERIKA J J | 2010 | The World Allergy Organization Journal2010，3，： | 1 |
| 10 | A double-blind, placebocontrolled, crossover study of osmotic release oral system methylphenidate in adults with ADHD with assessment of oppositional and emotional dimensions of the disorder 显示文摘 | Frederick W Reimherr Erika D Williams | 2007 | J Clin Psychiatry2007，68，1： | 1 |
| 11 | High-yield preparation of wax esters via lipase-catalyzed esterification using fatty acids and alcohols from Crambe and Camelina oils 显示文摘 | Georg S Petra W Erika K | 2001 | Journal of the American Oil Chemists Society2001，49，2： | 1 |
| 12 | Passing to India: a critique of American football's expansion显示文摘 | ERIKA P ERIN W | 2014 | Media Culture Society July2014，36，5： | 1 |
| 13 | High spontaneous mutation rate in the hyperthermophilic archaeon Sulfolobus solfataricus is mediated by transposable elements显示文摘 | Erika Martusewitsch Christoph W Sensen Chrism Schleper | 2000 | Journal of Bacteriology2000，182，9： | 1 |
| 14 | Experimental reactivity parameters for toxicity modeling: application to the acute aquatic toxicity of SN2 electrophiles to Tetrahymena pyriformis显示文摘 | David W R Wayne S T Erika M W | 2010 | Chemical Research in Toxicology2010，23，1： | 1 |
| 15 | Me chanochemistry in the preparation of advanced materials显示文摘 | Balaz P Choi W S Martin Fabidn Erika Gododikovd | 2006 | Acta Montanistica Slovaca2006，11，2： | 1 |
| 16 | Potential of salix as phytoextractor for Cd on moderately contaminated soils显示文摘 | ERIKA K W JAN E | 2003 | Plant and soil2003，249，1： | 1 |
| 17 | Romidepsin (FK228) combined with cisplatin stimulates DNA damage - induced cell death in ovarian cancer显示文摘 | AndrewJW Anum SL Erika W | 2013 | Gynecol Oncol2013，128，3： | 1 |
| 18 | Nutrition and management of broiler to meet the retailer's requirement 显示文摘 | Erika M W | 2002 | Poultry International2002，41，4： | 1 |
| 19 | Polycyclic aromatic hydrocarbons ( PAHs ) in sediments of the Baltic Seaand of the Geman coastal waters 显示文摘 | Gesine W Erika T | 1999 | Chemosphere1999，38，7： | 1 |
| 20 | Neural Network Applications in Finance:A Practical Introduction显示文摘 | Krishnaswamy C Erika W Gilbert | 2000 | Financial Practice and Education2000，，05： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员