|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Molecular analysis of hepatitis B virus isolates in Mexico:Predominant circulation of hepatitis B virus genotype H显示文摘AIM: To determine the genotypes in Mexican hepatitis Bvirus (HBV) isolates and characterize their precore andcore promoter mutations.METHODS: Forty-nine HBV isolates of Mexico obtainedfrom sera of 15 hepatitis patients, 6 hemodialysis pa-tients, 20 men seeking HIV testing, and 8 AIDS patientswere analyzed. HBV isolates were amplified by PCR,and genotyped by line probe assay (INNO-LiPA HBVGenotyping; INNOGENETICS N V, Ghent, Belgium).HBV genotype confirmation was performed by DNAsequencing part of the sAg region. Precore and core pro-moter mutation characterization was performed by lineprobe assay (INNO-LiPA HBV PreCore; INNOGENETICS NV, Ghent, Belgium).RESULTS: Overall, HBV genotype H was found in 37(75.5%) out of the 49 isolates studied. HBV genotypesG, A, and D were found in 5 (10.2%), 4 (8.2%), and 3(6.1%) isolates, respectively. HBV genotype H was pre-dominant in isolates from hemodialysis patients (100%),hepatitis patients (80%), and men seeking HIV test-ing (75%), and accounted for half of infections in AIDSpatients (50%). Six (12.2%) out of the 49 HBV isolatesshowed both wild type and mutant populations at pre-core codon 28. These mixed wild type and precore mu-tant populations were observed in one HBV genotype Aisolate and in all HBV genotype G isolates. A dual variantcore promoter mutation was observed in 1 (2%) of theisolates, which was genotype H.CONCLUSION: HBV genotype H is highly predominantin HBV isolates of Mexico followed by genotypes G, Aand D. A low frequency of precore and core promotermutations is observed in HBV Mexican isolates. | Cosme Alvarado-Esquivel Erwin Sablon Carlos Jesús Conde-GonzálezNational Institute of Public Health Cuernavaca Morelos Mexico Luis Juárez-Figueroa Lilia Ruiz-Maya Sergio-Aguilar Benavides | 2006 | World Journal of Gastroenterology2006，12，40： | 6 |
| 2 | 硅油填充眼手法小切口与超声乳化白内障手术的并发症(英文)显示文摘目的:比较超声乳化联合硅油取出术与硅油填充眼手法小切口白内障手术(MSICS)的安全性。方法:回顾性对比研究。162例患者162眼接受白内障手术,超声乳化联合硅油取出术与硅油填充眼手法小切口白内障手术均行玻璃体切除。结果:超声乳化白内障手术组术后低眼压21眼(18.91%)MSICS组术后低眼压8眼(15.68%),两组间无明显统计学差异(P=0.666)。术后1mo两组间视网膜复位率无明显统计学意义;超声乳化白内障手术组8例患者(7.2%)复发,硅油填充眼手法小切口白内障手术组9例(17.64%)复发,两组复发率比较,差异无统计学意义(P=0.055)。结论:硅油填充眼手法小切口白内障手术相较于超声乳化联合硅取出术在低眼压、渗漏、脉络膜脱离、视网膜复位率方面结果无劣效性。 | Arief S Kartasasmita Ohisa Harley Mareta Gustianingsih Erwin Iskandar | 2018 | 国际眼科杂志2018，18，2： | 5 |
| 3 | Adiponectin and its receptors in rodent models of fatty liver disease and liver cirrhosis显示文摘AIM: To determine circulating and hepatic adiponectin in rodents with fatty liver disease or liver cirrhosis and investigate expression of the adiponectin receptors AdipoR1 on the mRNA and protein level and AdipoR2 on the mRNA level. METHODS: Fat fed rats were used as a model for fatty liver disease and bile duct ligation in mice to investigate cirrhotic liver. Expression of AdipoR1 and AdipoR2 mRNA was determined by real time RT-PCR. AdipoR1 protein was analysed by immunoblot. Adiponectin was measured by ELISA. RESULTS: Systemic adiponectin is reduced in fat- fed rats but is elevated in mice after bile duct ligation (BDL). Hepatic adiponectin protein is lower in steatotic liver but not in the liver of BDL-mice when compared to controls. Adiponectin mRNA was not detected in human liver samples or primary human hepatocytes nor in rat liver but recombinant adiponectin is taken up by isolated hepatocytes in-vitro. AdipoR1 mRNA and AdipoR1 protein levels are similar in the liver tissue of control and fat fed animals whereas AdipoR2 mRNA is induced. AdipoR2 mRNA and AdipoR1 mRNA and protein is suppressed in the liver of BDL-mice. CONCLUSION: Our studies show reduced circulating adiponectin in a rat model of fatty liver disease whereas circulating adiponectin is elevated in a mouse model of cirrhosis and similar fi ndings have been described in humans. Diminished hepatic expression of adiponectinreceptors was only found in liver cirrhosis. | Markus Neumeier Claus Hellerbrand Erwin Gbele Roland Buettner Cornelius Bollheimer Johanna Weigert Andreas Schffler Thomas S Weiss Monika Lichtenauer Jürgen Schlmerich Christa Buechler | 2006 | World Journal of Gastroenterology2006，12，34： | 4 |
| 4 | Neutralization-chemical reionization mass spectrometry 显示文摘 | Erwin K M Gronert S Barlow S E | 1990 | J Am Chem Soc1990，112，： | 1 |
| 5 | Acute pancreatitis: value and impact of CT severity index显示文摘 | Alhajeri A Erwin S | 2008 | Abdom Imaging2008，33，1： | 1 |
| 6 | A three degrees-of-freedom adaptive-passive isola- tor for launch vehicle payloads显示文摘 | KHORRAMI F RASTEGAR J R ERWIN R S | 2000 | SPIE2000，3991，： | 1 |
| 7 | Inventory control in hybrid systems with remanufaeturing显示文摘 | ERWIN V D MARCM L S ROMMET D | 1999 | Management Science1999，145，5： | 1 |
| 8 | U/Pb zircon geochronology and tempo of the end-Permian mass extinction 显示文摘 | Bowring S A Erwin D H Jin Y | 1998 | Science1998，280，： | 1 |
| 9 | Industrial Relations Climate,Attendance Behavior and the Role of Trade Unions显示文摘 | Deery S Erwin P Iverson R | | 0，，04： | 1 |
| 10 | Brain remodeling due to neuronal and astrocytic proliferation after controlled cortical injury in mice显示文摘 | Kernie S G Erwin T M Parada L F | 2001 | J Neurosci Res2001，66，3： | 1 |
| 11 | Evaluation of success rate and access time for an adult sternal intraosseous device deployed in the prehospital setting 显示文摘 | Byars D V Tsuchitani S N Erwin E | 2011 | Prehosp Disaster Med2011，26，2： | 1 |
| 12 | High-efficiency coupling-insensitive transcutaneous power and data transmission via an inductive link 显示文摘 | Clements M Z Erwin S H | 1990 | IEEE Transactions on Biomedical Engineering1990，37，7： | 1 |
| 13 | Lipopolyaccharide binding protein in acute pancreatitis 显示文摘 | Erwin PJ Lewis H Dolan S | 2000 | Cnt Cate Med2000，28，1： | 1 |
| 14 | The ORION statement: guidelines for transparent reporting of outbreak reports and intervention studies of nosocomial infection显示文摘 | Sheldon P Stone Ben S Cooper Chris C Kibbler Barry D Cookson Jenny A Roberts Graham F Medley Georgia Duckworth Rosalind Lai Shah Ebrahim Erwin M Brown Phil J Wiffen Peter G Davey | 2007 | The Lancet Infectious Diseases2007，，4： | 1 |
| 15 | Volatile fatty acid analyses of blood and rumen fluid by gas chromatography显示文摘 | Erwin S Marco G J Eemery E M | 1961 | Journal of Dairy Science1961，44，9： | 1 |
| 16 | A group-IV ferromagnetic semiconductor : Mnx Ge1-x 显示文摘 | PARK Y D HANBICKI A T ERWIN S C | 2002 | Science2002，295，5555： | 1 |
| 17 | U/Pb zircon geochronology and tempo of the end-Permian mass extinction显示文摘 | Bowring S A Erwin D H Jin Y G | 1998 | Science1998，280，： | 1 |
| 18 | U/Pb zircon geochronology and tempo of the end-Permian mass extinction 显示文摘 | Bowring S A Erwin D H Jin Y G | 1998 | Science1998，280，： | 1 |
| 19 | Receptor for advanced glycation endproduct(RAGE)-mediated nuclear factor-kappa B activation in vasculitic neuropathy显示文摘 | Haslbeck KM Bierhaus A Erwin S | 2004 | Muscle nerve2004，，29： | 1 |
| 20 | U/Pb zircon geochronology and tempo of the End-Permian mass extinction 显示文摘 | Bowring S A Erwin D H Jin Y G | 1998 | Science1998，280，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员