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| 1 | Comparison between endoscopic sphincterotomy vs endoscopic sphincterotomy associated with balloon dilation for removal of bile duct stones:A systematic review and meta-analysis based on randomized controlled trials显示文摘AIM To compare gallstones removal rate and incidence of bleeding, pancreatitis, use of mechanical lithotripsy, cholangitis and perforation between isolated sphincterotomy vs sphincterotomy associated with balloon dilation of papilla in choledocholithiasis through the meta-analysis of randomized clinical trials. METHODS We conducted a systematic review according to the PRISMA guidelines. Literature search was restricted to randomized controlled trials(RCTs) on Med Line, Cochrane Library, LILACS, and EMBASE database platforms in July 2017. The manual search included references of retrieved articles. We extracted data focusing on outcomes: The primary endpoint was the stones removal rate; Secondary endpoints were rates of pancreatitis, bleeding, use of mechanical lithotripsy(ML), perforation and cholangitis. RESULTS Eleven RCTs with 1824 patients were included. EST was associated with more post-endoscopic retrograde cholangiopancreatography(ERCP) bleeding [FE RD-0.02, CI(-0.03,-0.00), I2 = 33%, P = 0.05] and more need of mechanical lithotripsy in general [RE RD-0.16, CI(-0.25,-0.06), I2 = 90%, P = 0.002] and in subgroup analysis of stones greater than 15 mm [RE RD-0.20, CI(-0.38,-0.02), I2 = 82%, P = 0.003]. Incidence of pancreatitis [FE RD-0.01, CI(-0.03, 0.01), I2 = 0, P = 0.36], cholangitis [FE RD-0.00, CI(-0.01, 0.01), I2 =0, P = 0.97] and perforation [FE RD-0.01, CI(-0.01, 0.00), I2 = 0, P = 0.23] was similar between the groups as well as similar stone removal rates in general [FE RD-0.01, CI(-0.01, 0.04), I2 = 0, P = 0.23] and pooled analysis of stones greater than 15 mm [FE RD-0.02, CI(-0.02, 0.07), I2 = 11%, P = 0.31]. CONCLUSION Through meta-analysis of randomized clinical trials we found that isolated sphincterotomy was associated with more post-ERCP bleeding and more need for mechanical lithotripsy. However, there was no statistical difference in the stone removal rate between isolated sphincterotomy and sphincterotomy associated with balloon dilation in the approach to remove gallstones. | Cesar Capel de Clemente Junior Wanderley Marques Bernardo Tomazo Prince Franzini Gustavo Oliveira Luz Marcos Eduardo Lera dos Santos Jonah Maxwell Cohen Diogo Turiani Hourneaux de Moura Fábio Ramalho Tavares Marinho Martin Coronel Paulo Sakai Eduardo Guimaraes Hourneaux de Moura | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，8： | 8 |
| 2 | Mi- crocystins (cyanobacteria hepatotoxins) bioaccumula- tion in fish and crustaceans from Sepetiba Bay (Brasil, RJ) 显示文摘 | Magalhaes V F Marinho M M Domingos P | 2003 | Toxicon2003，42，3： | 1 |
| 3 | Foldable Artiflex phakic intraocular lens for the correction of myopia: two-year follow-up results of a prospective European multicenter study 显示文摘 | Dick HB Budo C Malecaze F Guell JL Marinho AA Nuijts RM | 2009 | Ophthalmology2009，116，4： | 1 |
| 4 | Hypercoagulability and lung cancer显示文摘 | Marinho F C Takagaki T Y | 2008 | J Bras Pneumol2008，34，： | 1 |
| 5 | Influence of N/P ratio on competitive abilities for nitrogen and phosphorus by Microcystis aeruginosa and Alacoseira distans 显示文摘 | Marinho M M De Oliveira E Azevedo S M F | 2007 | Aquatic Ecology2007，41，4： | 1 |
| 6 | Hypercoagulability and lung cancer显示文摘 | Marinho F C Takagaki T Y | 2008 | J Bras Pneumol Pneumol2008，34，5： | 1 |
| 7 | Microcystins ( cyanobacteria hepatotoxins ) bioaccumulation in fish and crustaceans from Sepetiba Bay( Brasil, RJ )显示文摘 | MAGALHAES V F MARINHO M M DOMINGOS P | 2003 | Toxicon2003，42，3： | 1 |
| 8 | Numerical calculation of fractional Fourier transforms with a single fast Fourier transform algorithm 显示文摘 | F J Marinho L M Bernardo | 1998 | J Opt Soc Am A1998，15，8： | 1 |
| 9 | Maytenus erythroxylon Reissek(Celastraceae) ethanol extract presents antidiarrheal activity via antimotility and antisecretory mechanisms显示文摘AIM To investigate the acute toxicity,phytochemical profile,antidiarrheal activity and mechanisms of action of Maytenus erythroxylon(M.erythroxylon)ethanol extract.METHODS A castor oil-induced diarrhea model was used to evaluate antidiarrheal activity.Intestinal transit and gastric emptying protocols were used to evaluate a possible antimotility effect.KATP channels,nitric oxide,presynapticα2-adrenergic and tissue adrenergic receptors were investigated to uncover antimotility mechanisms of action and castor oil-induced enteropooling to elucidate antisecretory mechanisms.RESULTS All tested doses of the extract(62.5,125,250 and 500 mg/kg)possessed antidiarrheal activity,with a significant decrease of the evacuation index.This activity is possibly related to a reduced gastric emptying(125,250 and 500 mg/kg)and to a decreased percentage of intestinal transit for all tested doses.That last effect seems to be modulated by nitric oxide,KATP channels and tissue adrenergic receptors.Besides,the extract also presented antisecretory effect due to a decrease of intestinal fluid accumulation.CONCLUSION The antidiarrheal effect of M.erythroxylon found in this study involves antimotility and antisecretory mechanisms that may be attributed to the chemical compounds found in this species:saponins,flavonoids,tannins,triterpenes and steroids. | Rodrigo de Oliveira Formiga Zelma Glebya Maciel Quirino Margareth de Fátima Formiga Melo Diniz Alexsandro Fernandes Marinho Josean Fechine Tavares Leonia Maria Batista | 2017 | World Journal of Gastroenterology2017，23，24： | 1 |
| 10 | Numerical calculation of fractional Fourier transform with a single fast Fourier transform algorithm显示文摘 | F Marinho L M Bemardo | 1998 | Opt Soc Am1998，15，8： | 1 |
| 11 | Allograft conjunctival transplantation for bilateral ocular surface disorders 显示文摘 | Kwitko S Marinho D Barcaro S Bocaccio F Rymer S Fernandes S | 1995 | Ophthalmology1995，102，7： | 1 |
| 12 | Corneal ectasia after LASIK-how to manage显示文摘 | Marinho A Pinto MC Vaz F | 2000 | Semin Ophthalmol2000，15，1： | 1 |
| 13 | Coronary revascularization in the treatment of moderate and severe postischemic left ventricular dysfunction显示文摘 | Fath-Ordoubadi F Pagano D Marinho NV | 1998 | Am J Cardiol1998，82，1： | 1 |
| 14 | Numerical calculation of fractional Fourier transform with a single fast Fourier transform algorithm显示文摘 | F Marinho L M Bernardo | 1998 | J Opt Soc Am1998，15，8： | 1 |
| 15 | Minimally invasive percutaneous stabilization plus balloon kyphoplasty for the treatment of type A thoraco lumbar spine fractures: minimum 4 year's follow-up 显示文摘 | Zairi F Aboukais R Marinho P | 2014 | J Neurosurg Sci2014，58，3： | 1 |
| 16 | Clinical usefulness of B-type natriuretic peptide in the diagnosis of pleural effusions due to heart failure显示文摘 | MARINHO F C VARGAS F S FABRI J Jr | 2011 | Respirology2011，16，3： | 1 |
| 17 | 显示文摘 | Maroccos R Vaz F Marinho A | 2001 | Ophthalmology2001，98，11： | 1 |
| 18 | Biochimica et Biophysica Acta显示文摘 | Antunes F Marinho H S Barreto M C Pavao M L Pinto R E | 2003 | 1624:112003，1624，： | 1 |
| 19 | Nosocomial fungaemia: a 2-year prospective study显示文摘 | Costa S F Marinho I Araujo E A | 2000 | J Hosp Infect2000，45，1： | 1 |
| 20 | The filter paper method revisited显示文摘 | Marinho F A M Oliveira O M | 2006 | Geotechnical Testing Journal2006，29，25： | 1 |
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