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| 1 | Embolization of splenorenal shunt associated to portal vein thrombosis and hepatic encephalopathy显示文摘Hepatic encephalopathy(HE)is a cognitive disturbance characterized by neuropsychiatric alterations.It occurs in acute and chronic hepatic disease and also in patients with portosystemic shunts.The presence of these portosystemic shunts allows the passage of nitrogenous substances from the intestines through systemic veins without liver depuration.Therefore,the embolization of these shunts has been performed tocontrol HE manifestations,but the presence of portal vein thrombosis is considered a contraindication.In this presentation we show a cirrhotic patient with severe HE and portal vein thrombosis who was submitted to embolization of a large portosystemic shunt.Case report:a 57 years-old cirrhotic patient who had been hospitalized many times for persistent HE and hepatic coma,even without precipitant factors.She had a wide portosystemic shunt and also portal vein thrombosis.The abdominal angiography confirmed the splenorenal shunt and showed other shunts.The larger shunt was embolized through placement of microcoils,and the patient had no recurrence of overt HE.There was a little increase of esophageal and gastric varices,but no endoscopic treatment was needed.Since portosystemic shunts are frequent causes of recurrent HE in cirrhotic patients,portal vein thrombosis should be considered a relative contraindication to perform a shunt embolization.However,in particular cases with many shunts and severe HE,we found that one of these shunts can be safely embolized and this procedure can be sufficient to obtain a good HE recovery.In conclusion,we reported a case of persistent HE due to a wide portosystemic shunt associated with portal vein thrombosis.As the patient had other shunts,she was successfully treated by embolization of the larger shunt. | Letícia de Campos Franzoni Fábio Cardoso de Carvalho Rafael Gomes de Almeida Garzon Fábio da Silva Yamashiro Laís Augusti Lívia Alves Amaral Santos Mariana de Souza Dorna Júlio Pinheiro Baima Talles Bazeia Lima Carlos Antonio Caramori Giovanni Faria Silva Fernando Gomes Romeiro | 2014 | World Journal of Gastroenterology2014，20，42： | 6 |
| 2 | 中医药在巴西的发展现状与分析显示文摘巴西医疗保险以统一医疗体系(Unified Health System,SUS)的免费医疗为主、私人保险为补充,已实现全民享有基本医疗服务。导致该国居民死亡的主要疾病是缺血性心脏病、脑卒中、下呼吸道感染,近年来AD、慢性肾脏病及糖尿病的发病率显著增高。以针灸为代表的中医疗法在19世纪初传入巴西,目前针灸治疗已得到较广泛的认可和应用,被纳入SUS,并在多所高校开设相关课程,但中医药整体特色有待加强,从业人员对中药的理解、运用不足,以及中医药教育缺乏规范等问题限制了中医药在巴西的发展。建议通过发挥中医药治未病的特色,加大中药研发力度并扩大市场,规范中医教育等措施,促进两国在中医药领域的广泛合作,推动中医药在巴西的发展与传播。 | 李皓月 党迎迎 Thaís Salles Araujo Fatima Terezinha Pelachini Farias Jaime Amador Soares Graciela Mendonça da Silva de Medeiros 于涛 魏竞竞 赵静 许家杰 曹洪欣 | 2021 | 国际中医中药杂志2021，43，5： | 5 |
| 3 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 4 | Compartive analysis of two different subunits of antigen B from Echinococcus granulosus:gene sequences,expression in Escherichia coli and serological evaluation显示文摘 | Rott MB Femandez V Farias S | 2000 | Acta Trop2000，75，3： | 1 |
| 5 | Impact of FDG-PET/ CT on radiotherapy volume delineation in non-small-cell lung cancer and correlation of imaging stage with pathologic findings显示文摘 | Faria SL Menard S Devic S | 2007 | Int J Radiat Oncol Biol Phys2007，7，： | 1 |
| 6 | Relationship of PON1 192 and 55 gene polymorphisms to calcific valvular aortic stenosis显示文摘 | Moura LM Faria S Brito M | 2012 | Am J Cardiovasc Dis2012，2，： | 1 |
| 7 | Mycoinsecticides and mycoacaricides: a comprehensive list with worldwide coverage and international classification of formulation types 显示文摘 | Faria M R Wraight S P | 2007 | Biological Control2007，43，： | 1 |
| 8 | Mercury contamination in farmed fish setup on former garimpo mining areas in the Northern Mato Grosso State, Amazonian region, Brazil显示文摘 | Farias R A Hacon S Campos R C | 2005 | Science of the Total Environment2005，348，13： | 1 |
| 9 | Apoptosis induced by prolonged exposure to odorants in cultured ceils from rat olfactory epithelium 显示文摘 | Brauchi S Cea C Farias JG | 2006 | Brain Res2006，1103，1： | 1 |
| 10 | Impact of FDG - PET/ CT on radiotherapy volume delineation in non-small-cell lung cancer and correlation of imaging stage with pathologic fingings 显示文摘 | Farias L Menard S Devic S | 2008 | Int J Radiat Oneol Biol Phys2008，70，4： | 1 |
| 11 | Plasma metalloproteinase activity is enhanced in the euglobulin fraction of breast and lung cancer patients显示文摘 | Farias E Ranuncolo S Cresta C | 2000 | Int J Cancer2000，89，4： | 1 |
| 12 | In Vitro studies of the effects of aflotoxin B1 and fu- monisin B1 on trypsin-like and collagenase-like activity from the hepatopancreas of white: shrimp (Litopanaeus van- namei)显示文摘 | Burgos-Hemandez A Farias S I Torres-Arreola W | 2005 | Aquaculture2005，250，： | 1 |
| 13 | Anticancer, antichemotactic and antimicrobial activities of marine sponges collected off the coast of Santa Catarina, southern Brazil显示文摘 | Noel R Monks Clea Lerner Amélia T Henriques Fabiane M Farias Elfrides E.S Schapoval Edna S Suyenaga Adriana B da Rocha Gilberto Schwartsmann Beatriz Mothes | 2002 | Journal of Experimental Marine Biology and Ecology2002，，1： | 1 |
| 14 | Mechanisms of infection of plants by nitrogen fixing organisms 显示文摘 | Sprent J I de Faria S M | 1988 | Plant and Soil1988，110，2： | 1 |
| 15 | CT evaluation of the response of gastrointestinal stromal tumors after imatinib mesylate treatment: a quantitative analysis correlated with FDG PET findings显示文摘 | Choi H Charnsangavej C de Castro Faria S | 2004 | Am J Roentgenol2004，183，6： | 1 |
| 16 | Helicobacter pylori eradication does not influence gastroesophageal reflux disease: a prospective, parallel, randomized, open-label, controlled trial 显示文摘 | Rodrigues LJ Faria CM Geocze S | 2012 | Arq Gastroenterol2012，49，1： | 1 |
| 17 | Wnt-7a induces presyn- aptic colocalization of alpha 7-nicotinic acetylcholine receptors and ade- nomatous polyposis coli in hippocampal neurons 显示文摘 | Farias G G Valles A S Colombres M | 2007 | J Neurosci2007，27，20： | 1 |
| 18 | Nanosized and re- usable SiO2/ZrO2 catalyst for highly efficient biodiesel production by soybean ktransesterification显示文摘 | Faria E A Marques J S Dias I M | 2009 | Braz Chem Soc2009，20，： | 1 |
| 19 | Assessment of 4- (5-)methylimidazole in soft drinks and dark beer显示文摘 | S C Cunha A I Barrado M A Faria et a/ | 2011 | Journal of Food Composition and Analysis2011，24，： | 1 |
| 20 | Neutrophil CD64 expression as an important diagnostic marker of infectionand sepsis inhospital patients显示文摘 | Farias MG de Lucena NP Dalbo S | 2014 | J lmmunol Methods2014，414，： | 1 |
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