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1Research advances on the multiple uses of Moringa oleifera: a sustainable alternative for socially neglected population显示文摘Moringa oleifera Lam(Moringaceae) is a plant with high nutritional and medicinal value. Native to India, it is now widely distributed throughout tropical and subtropical regions of the world. Its different parts are sources of proteins, vitamins and minerals and present different pharmacological and biotechnological potential. Moreover, M. oleifera seeds are widely used in water and effluent treatment, for their coagulation, flocculation and sedimentation properties, their ability of improving water quality, by reducing organic matter and microbial load, with special applicability in intensive animal production systems, such as aquaculture. In addition, due to its high nutritional value and several medicinal properties, this tree may act as a nutritional and medical alternative for socially neglected populations. In this context, this review gathers information on M. oleifera, emphasizing its chemical constituents, nutritional, pharmacological and antimicrobial properties, applications in the treatment of water effluents, and ecological and social aspects.Raimunda Samia Nogueira Brilhante Jamille Alencar Sales Vandbergue Santos Pereira Débora de Souza Collares Maia Castelo-Branco Rossana de Aguiar Cordeiro Célia Maria de Souza Sampaio Manoel de Araújo Neto Paiva Joao Bosco Feitosa dos Santos JoséJúlio CostaSidrim Marcos Fábio Gadelha Rocha 2017Asian Pacific Journal of Tropical Medicine2017,10,7:10
2螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 2018中华高血压杂志2018,26,3:7
3Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil.Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari 2019World Journal of Gastroenterology2019,25,38:2
4Severe bleeding after nephrolithotomy:resuhs of hyerselective embolization 显示文摘MARTIN X MURAT F J FEITOSA L C 2000Eur Urol2000,37,:1
5Inheritance of the waist-to-hip ratio in the national heart, lung, and blood institute family heart study 显示文摘FEITOSA M F BORECKI I STEVEN C 2000Obesity Research2000,8,:1
6Efeito da pimenta rosa assoeiada a diversas dosagens de antibioticos em frangos de eorte显示文摘Gonealves F G Zanini S F Feitosa S F 2012Cieneia Rural2012,,8:1
7Severe bleeding after nephrolithotomy:Results of hyperselective embolization 显示文摘MARTIN X MURAT F J FEITOSA L C 2000Eur Urol2000,37,:1
8Severe bleeding aiter nephrol- ithotomy:results ofhyperselective ambolization 显示文摘Martin X Murat F J Feitosa L C 2000Eur Urol2000,37,:1
9Severe bleeding after nephrolithotomy: results of hyperselective embolization显示文摘Martin X Murat F J Feitosa L C 2000Eur Urol2000,37,:1
10Liquid- liquid equilibrium for ternary mixtures of biodiesel (soybean or sunflower) + glycerol + ethanol at different temperatures 显示文摘Mesquita F M R Feitosa F X Sombra N E 2011Journal of Chemical & Engineering Data2011,56,11:1
11Reconstruction of electrical impedance tomography images using particle swarm optimization,genetic algorithms and non-blind search显示文摘FEITOSA R S RIBEIRO R R BARBOSA V F 2014Biosignals and Robotics for Better and Safer Living(BRC)2014,,5:1
12Sequence variation of the alpha-lactalbumin gene in Holstein and Nellore cows显示文摘Martins L F Milazzotto M P Feitosa W B 0,,03:1
13Phase diagrams of a CTAB/organic solvent/buffer system applied to extraction of enzymes by reverse micelles 显示文摘Feitosa E Catelam K T Hasmann F A 2008Journal of Chromatography B2008,862,12:1
14Multi-agent simulator for urban segre- gation (MASUS): A tool to explore alternatives for promoting inclusive cities显示文摘FEITOSA F LE Q B VLEK P L G 2011Computers environment and urban systems2011,35,2:1
15A new covariance estimate for bayesian classifiers in biometric recognition显示文摘 GILLIES D F FEITOSA R Q 2004IEEE Transactions on Circuits and Systems for Video Technology Special Issue on Image-and Video-Based Biometrics2004,14,2:1
16Severe bleedingafter nephrolithotomy:results of hyerselective embolization显示文摘Martin X Murat F J Feitosa L C 2000Eur Urol2000,37,:1
17Severe bleeding after nephrolithotomy:results of hyperselective embolization显示文摘MARTIN X MURAT F J FEITOSA L C 2000Eur Urol2000,37,:1
18Severe bleed ing after nephrolithotomy: results of hyperselective em bolization显示文摘Martin X Murat F J Feitosa L C 2000Eur Urol2000,37,13:1
19Severe bleeding after nephrolithotomy: result of hyperselective embolization 显示文摘Martin X Murat F J Feitosa LC 2000Eur Urol2000,37,:1
20Severe bleeding after nephrolithotomy results of hyperselective embolization显示文摘MARTIN X MURAT F J FEITOSA L C 2000Eur Urol2000,37,2:1
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