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| 1 | Management of lumbar zygapophysial (facet) joint pain显示文摘AIM: To investigate the diagnostic validity and therapeutic value of lumbar facet joint interventions in managing chronic low back pain.METHODS: The review process applied systematic evidence-based assessment methodology of controlled trials of diagnostic validity and randomized controlled trials of therapeutic efficacy. Inclusion criteria encompassed all facet joint interventions performed in a controlled fashion. The pain relief of greater than 50% was the outcome measure for diagnostic accuracy assessment of the controlled studies with ability to perform previously painful movements, whereas, for randomized controlled therapeutic efficacy studies, the primary outcome was significant pain relief and the secondary outcome was a positive change in functional status. For the inclusion of the diagnostic controlled studies, all studies must have utilized either placebo controlled facet joint blocks or comparative local anesthetic blocks. In assessing therapeutic interventions, short-term and long-term reliefs were defined as either up to 6 mo or greater than 6 mo of relief. The literature search was extensive utilizing various types of electronic search media including Pub Med from 1966 onwards, Cochrane library, National Guideline Clearinghouse, clinicaltrials.gov, along with other sources includingprevious systematic reviews, non-indexed journals, and abstracts until March 2015. Each manuscript included in the assessment was assessed for methodologic quality or risk of bias assessment utilizing the Quality Appraisal of Reliability Studies checklist for diagnostic interventions, and Cochrane review criteria and the Interventional Pain Management Techniques- Quality Appraisal of Reliability and Risk of Bias Assessment tool for therapeutic interventions. Evidence based on the review of the systematic assessment of controlled studies was graded utilizing a modified schema of qualitative evidence with best evidence synthesis, variable from level Ⅰ to level Ⅴ.RESULTS: Across all databases, 16 high quality diagnostic accuracy studies were identified. In addition, multiple studies assessed the influence of multiple factors on diagnostic validity. In contrast to diagnostic validity studies, therapeutic efficacy trials were limited to a total of 14 randomized controlled trials, assessing the efficacy of intraarticular injections, facet or zygapophysial joint nerve blocks, and radiofrequency neurotomy of the innervation of the facet joints. The evidence for the diagnostic validity of lumbar facet joint nerve blocks with at least 75% pain relief with ability to perform previously painful movements was level Ⅰ, based on a range of level Ⅰ to Ⅴ derived from a best evidence synthesis. For therapeutic interventions, the evidence was variable from level Ⅱ to Ⅲ, with level Ⅱ evidence for lumbar facet joint nerve blocks and radiofrequency neurotomy for long-term improvement(greater than 6 mo), and level Ⅲ evidence for lumbosacral zygapophysial joint injections for short-term improvement only.CONCLUSION: This review provides significant evidence for the diagnostic validity of facet joint nerve blocks, and moderate evidence for therapeutic radiofrequency neurotomy and therapeutic facet joint nerve blocks in managing chronic low back pain. | Laxmaiah Manchikanti Joshua A Hirsch Frank JE Falco Mark V Boswell | 2016 | World Journal of Orthopedics2016，7，5： | 9 |
| 2 | Prospective evaluation of small bowel preparation with bisacodyl and sodium phosphate for capsule endoscopy显示文摘AIM: To determine the effect of Prepacol?, a com- bination of sodium phosphate and bisacodyl, on transit and quality of capsule endoscopy (CE). METHODS: Fivety two consecutive patients were included in this prospective study. CE was performed following a 12 h fasting period. Twenty six patients were randomized for additional preparation with Prepacol?. The quality of CE was assessed separately for the proximal and the distal small bowel by 3 experienced endoscopists on the basis of a graduation which was initially developed with 20 previous CE. RESULTS: Preparation with Prepacol? accelerated small bowel transit time (262 ± 55 min vs 287 ± 97 min), but had no effect on the quality of CE. Visibility was significantly reduced in the distal compared to the proximal small bowel. CONCLUSION: The significantly reduced visibility of CE in the distal small bowel allocates the need for a good preparation. Since Prepacol? has no beneficial effect on CE the modality of preparation and the ideal time of application remains unclear. Further standardized examinations are necessary to identify sufficient preparation procedures and to determine the impact of the volume of the preparation solution. | Andreas Franke Frank Hummel Phillip Knebel Christoph Antoni Ulrich Bcker Manfred V Singer Matthias Lhr | 2008 | World Journal of Gastroenterology2008，14，13： | 5 |
| 3 | Trends in treatment and overall survival among patients with proximal esophageal cancer显示文摘BACKGROUND The management of proximal esophageal cancer differs from that of tumors located in the mid and lower part of the esophagus due to the close vicinity of vital structures.Non-surgical treatment options like radiotherapy and definitive chemoradiation(CRT)have been implemented.The trends in(non-)surgical treatment and its impact on overall survival(OS)in patients with proximal esophageal cancer are unclear,related to its rare disease status.To optimize treatment strategies and counseling of patients with proximal esophageal cancer,it is therefore essential to gain more insight through real-life studies.AIM To establish trends in treatment and OS in patients with proximal esophageal cancer.METHODS In this population-based study,patients with proximal esophageal cancer diagnosed between 1989 and 2014 were identified in the Netherlands Cancer Registry.The proximal esophagus consists of the cervical esophagus and the upper thoracic section,extending to 24 cm from the incisors.Trends in radiotherapy,chemotherapy,and surgery,and OS were assessed.Analyses were stratified by presence of distant metastasis.Multivariable Cox proportional hazards regression analyses was performed to assess the effect of period of diagnosis on OS,adjusted for patient,tumor,and treatment characteristics.RESULTS In total,2783 patients were included.Over the study period,the use of radiotherapy,resection,and CRT in non-metastatic disease changed from 53%,23%,and 1%in 1989-1994 to 21%,9%,and 49%in 2010-2014,respectively.In metastatic disease,the use of chemotherapy and radiotherapy increased over time.Median OS of the total population increased from 7.3 mo[95%confidence interval(CI):6.4-8.1]in 1989-1994 to 9.5 mo(95%CI:8.1-10.8)in 2010-2014(logrank P<0.001).In non-metastatic disease,5-year OS rates improved from 5%(95%CI:3%-7%)in 1989-1994 to 13%(95%CI:9%-17%)in 2010-2014(logrank P<0.001).Multivariable regression analysis demonstrated a significant treatment effect over time on survival.In metastatic disease,median OS was 3.8 mo(95%CI:2.5-5.1)in 1989-1994,and 5.1 mo(95%CI:4.3-5.9)in 2010-2014(logrank P=0.26).CONCLUSION OS significantly improved in non-metastatic proximal esophageal cancer,likely to be associated with an increased use of CRT.Patterns in metastatic disease did not change significantly over time. | Judith de Vos-Geelen Sandra ME Geurts Liselot BJ Valkenburg-van Iersel Evelien JM de Jong Vivianne CG Tjan-Heijnen Margreet van Putten Valery EPP Lemmens Heike I Grabsch Nadia Haj Mohammad Frank JP Hoebers Chantal V Hoge Paul M Jeene Hanneke WM van Laarhoven Tom Rozema Marije Slingerland Grard AP Nieuwenhuijzen | 2019 | World Journal of Gastroenterology2019，25，47： | 2 |
| 4 | Decreased hemispheric aquaporin-4 is linked to evolving brain edema following controlled cortical impact injury in rats 显示文摘 | Kiening KL Frank KH Landeghem V | 2002 | Neurosci Lett2002，324，2： | 2 |
| 5 | The Nature of Systems Biology 显示文摘 | Bruggeman Frank J Hans V Westerhoff | 2006 | Trends in Microbiology2006，15，1： | 1 |
| 6 | Choosing Among Safety Improvement Strategies:A Discussion with Example of Risk Assessment and Multi-criteria Decision Approaches for NASA显示文摘 | | 1995 | Reliability Engineering and System1995，49，： | 1 |
| 7 | Effects of three pharmaceutical and personal care products on natural freshwater algal assemblages显示文摘 | Wilson B A Smith V H Frank D J R | 2003 | Environ Sci Technol2003，37，9： | 1 |
| 8 | Output characterization of frequency shifted feedback laser: theory and experiment显示文摘 | Paul D Hale Frank V Kowalski | 1990 | IEEE J QE1990，26，10： | 1 |
| 9 | Direct Analysis of Oxidizing Agents in Aqueous Solution with Attenuated Total Reflectance Mid-Infrared Spectroscopy and Diamond-like Carbon Protected Waveguides显示文摘 | MARKUS J FRANK V VORABERGER H S | 2004 | Analytical Chemistry2004，76，2： | 1 |
| 10 | Sample preparation for total nitrogen and 15N-Rtion analysis by the automated Dumas combustion method显示文摘 | Frank V Schindler Raymond E Knighton | 1999 | Communications in soil science and plant analysis1999，30，910： | 1 |
| 11 | Oral N-carbamylglu- tamate supplementation inereases protein synthesis in skeletal muscle of piglets显示文摘 | Frank J W Escobar J Nguyen H V | 2007 | J Nutr2007，137，2： | 1 |
| 12 | Traffic network state esti- mation using extended Kalman filtering and DSMART 显示文摘 | FRANK Z HANS L V HANS V K | 2006 | IFAC Proceedings Volumes2006，11，1： | 1 |
| 13 | Cytochrome P450 family member CYP704B2 catalyzes the omega } - hydrnxylation of fatty acids and is required for anther cutin biosynthesis and pollen exine formation in rice 显示文摘 | Li H Pinot F Sauveplane V Werck-Reichhart D Diehl P Schreiber L Franke R Zhang P Chert L Gao Y Liang W ZhangD | 2010 | Plant Cell2010，22，1： | 1 |
| 14 | The formation of passivaring internal In2 03 bands in Silver-Indium alloys 显示文摘 | R A Rapp D F Frank J V Armitage | 1964 | Acta Metall1964，12，： | 1 |
| 15 | Choosing among safety improvement strategies:discussion with example of risk assessment and multi-criteria decision approaches for NASA显示文摘 | | 1995 | Reliability Engineering and System1995，49，： | 1 |
| 16 | ζ potential of nanoparticle suspensions:effect of electrolyte concentration,particle size,and volume fraction显示文摘 | Franks G V Healy T W | 2008 | Journal of the American Ceramic Society2008，91，4： | 1 |
| 17 | A materials se- lection protocol for lightweight actively cooled panels显示文摘 | Lorenzo V Natasha V Frank W Z | 2008 | Journal of Applied Mechanics2008，75，6： | 1 |
| 18 | Relative biological effectivness in terms of tumor response of 125I implants compared with 60Co gannna rays显示文摘 | Shidey L Brigitte R Frank V | | 0，，03： | 1 |
| 19 | Venous thromboem- bolism after spinal cord injury: incidence, time course, and associated risk factors in 16, 240 adults and children 显示文摘 | Jones T Ugalde V Franks P | 2005 | Arch Phys Med Rehabil2005，86，12： | 1 |
| 20 | Endoscopic treatment of benign tumors of the nose and paranasal sunuses: a report of 33 cases显示文摘 | SCIARRETTA V PASQUINI E FRANK G | 2006 | Am J Rhinol2006，20，1： | 1 |
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