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| 1 | Sustained virological response based on rapid virological response in genotype-3 chronic hepatitis C treated with standard interferon in the Pakistani population显示文摘AIM:To document the sustained virological response (SVR) in rapid virological responders (RVR) of genotype-3 chronic hepatitis C with standard interferon (SdIF). METHODS:Hepatitis C genotype-3 patients during the period July 2006 and June 2007 were included. Complete blood counts, prothrombin time, ALT, albumin, qualitative HCV RNA were done. SdIF and ribavirin were given for 4 wk and qualitative HCV RNA was repeated. Those testing negative were allocated to group-A while the rest were allocated to group-B. Treatment was continued a total of 16 and 24 wk for group A and B respectively. HCV RNA was repeated after 24 wk of treatment. End virological and sustained virological responses were compared by χ2 test. ROC of pretreatment age, ALT and albumin were plotted for failure to achieve SVR. RESULTS:Of 74 patients treated, RCV RNA after 16 wk of therapy became undetectable in 34 (45.9%) and was detectable in 40 (54.1%) and were allocated to groups A and B respectively. SVR was achieved in 58.8% and 27.8% in groups A and B respectively. SVR rates were significantly higher in patients who had RVR as compared to those who did not (P = 0.0;γ = 2). Both groups combined ETR and SVR were 70% and 33% respectively. ROC plots of pretreatment age, ALT and albumin for SVR showed only ALT to have a significantly large area under the curve.CONCLUSION:SVR rates were higher in patients who had RVR with SdIF and high pre treatment ALT values correlated to probability of having RVR. | Bader Faiyaz Zuberi Faisal Faiyaz Zuberi Sajjad Ali Memon Muhammad Hafeez Qureshi Sheikh Zafar Ali Salahuddin Afsar | 2008 | World Journal of Gastroenterology2008，14，14： | 3 |
| 2 | Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases显示文摘 | Sung-Jun Park Faiyaz Ahmad Andrew Philp Keith Baar Tishan Williams Haibin Luo Hengming Ke Holger Rehmann Ronald Taussig Alexandra L. Brown Myung K. Kim Michael A. Beaven Alex B. Burgin Vincent Manganiello Jay H. Chung | 2012 | Cell2012，，3： | 2 |
| 3 | A prospective randomized study between transurethral vaporization using plasmakinetic energy and transurethral reseetion of the prostate显示文摘 | Faiyaz MK Poonambalam C Jaspal V | 2003 | J Urol2003，169，4： | 1 |
| 4 | Alopecia universalis associated with a mutation in the human hairless gene显示文摘 | Ahmad W Faiyaz ul Haque M Brancolini V | 1998 | Science1998，279，5351： | 1 |
| 5 | Distinct,autosomal recessive form of spondyloepimetaphyseal dysplasia segregating in an inbred Pakistani kindred显示文摘 | AHMAD M FAIYAZ Ul HAQUE M | | 0，，05： | 1 |
| 6 | Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse显示文摘 | FAIYAZ UL HAQUE M KING LM KRAKOW D | | 0，，02： | 1 |
| 7 | Association between blood pressure, ultrafiltration, and hemodialysis graft throm- bosis: a multivariable logistic regression analysis显示文摘 | Paulson WD Ram SJ Faiyaz R | 2002 | Am J Kidney Dis2002，40，4： | 1 |
| 8 | Interstitial laser ablation(Indigo TM)of the prostate-arandomized prospective study,Three years follow up显示文摘 | Jaspal Ponnambalm Faiyaz | 2001 | Jurol2001，，： | 1 |
| 9 | A prospective randomized study between transurethral vaporization using plasmakinetic energy and transurethral resection of the prostate显示文摘 | Faiyaz MK Poonambalam C Jaspal V | 2003 | J Urol2003，169，4： | 1 |
| 10 | Autoimmune polyglandular syndrome type 1 in Saudichildren显示文摘 | Bin Abbas BS Faiyaz U1 Haque M Al Fares AH | 2010 | Saudi Med J2010，31，7： | 1 |
| 11 | Development and bioavailability assessment of ramipril nanoemulsion formulation显示文摘 | Sheikh Shafiq Faiyaz Shakeel Sushma Talegaonkar Farhan J. Ahmad Roop K. Khar Mushir Ali | 2006 | European Journal of Pharmaceutics and Biopharmaceutics2006，，2： | 1 |
| 12 | Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases显示文摘 | Sung-Jun Park Faiyaz Ahmad Andrew Philp Keith Baar Tishan Williams Haibin Luo Hengming Ke Holger Rehmann Ronald Taussig Alexandra L. Brown Myung K. Kim Michael A. Beaven Alex B. Burgin Vincent Manganiello Jay H. Chung | 2012 | Cell2012，，： | 1 |
| 13 | Aprostive randomisedstudy between transurethral vaporisationusing plasmakinetic energy显示文摘 | Virdi Faiyaz K Ponnambalam Chandrasekar | 2001 | Jurol2001，，： | 1 |
| 14 | Mutation in the cartilage - derived morphogenetic protein - 1 ( CDMP1 ) gene in a kindred affected with fibular hypoplasia and complex brachydactyly ( DuPan syndrome) 显示文摘 | Faiyaz - UI - Haque M Ahmad W Zaidi SH | 2002 | Clin Genet2002，61，6： | 1 |
| 15 | Development and bioavailability assessment of ramipra nanoemulsion formulation 显示文摘 | SHEIKH S FAIYAZ S SUSHMA T | 2007 | European Journal of Pharmaceutics and Biopharmaceutics2007，66，2： | 1 |
| 16 | Measurement and correlation of solubility of diosmin in four pure solvents and β-cyclodextrin solution at 298.15K to 333.15K显示文摘The aim of present study was to measure and correlate the solubility of poorly water-soluble flavonoid diosmin in water, ethanol, isopropyl alcohol(IPA), polyethylene glycol-400(PEG-400) and β-cyclodextrin(β-CD) aqueous solution(0.02 mol·L-1). The solubility of diosmin was measured using the shake flask method from(298.15 to333.15) K at atmospheric pressure. The experimental solubilities of diosmin were regressed by the modified Apelblat model with a relative deviation in the range of 0.048% to 5.940%. The correlation coefficients were observed in the range of 0.9957 to 0.9995. The solubility of diosmin was found to be increased with temperature in all sample matrices investigated. The mole fraction solubility of diosmin was found to be higher in β-CD aqueous solution and PEG-400 as compared to water, ethanol and IPA. Based on solubility data of present study, diosmin was considered as practically insoluble in water, insoluble in ethanol & IPA and soluble in PEG-400 and β-CD aqueous solution. | Md Khalid Anwer Faiyaz Shakeel | 2015 | Chinese Journal of Chemical Engineering2015，23，5： | 1 |
| 17 | Novel mutations in the EXT1 gene in two consanguineous families affected with multiple hereditary exostoses (familial osteo-chondromatosis) 显示文摘 | Faiyaz U1 Haque M Ahmad W Zaidi S | 2004 | Clin Genet2004，66，2： | 1 |
| 18 | A prostive randomised study between transurethral vaporisation using plasmakinetic energy显示文摘 | Virdi Faiyaz K Ponnambalam Chandrasekar | | J Urol0，，： | 1 |
| 19 | Alopecia universalis associated with a mutation in the human hairless gene显示文摘 | Ahmad W Faiyaz ul Haque M Brancolini V | 1998 | Science1998，279，5351： | 1 |
| 20 | Development and bioavailability assessment of ramipril nanoemulsion formulation显示文摘 | Sheikh Shafiq Faiyaz Shakeel Sushma Talegaonkar | 2006 | European Journal of Pharmaceutics and Biopharmaceutics2006，，6： | 1 |
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