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	题名	作者	年代	出处	被引量
1	Botulinum toxin associated with fissurectomy and anoplasty for hypertonic chronic anal fissure: A case-control study显示文摘BACKGROUND Lateral internal sphincterotomy is still the approach of choice for the treatment of chronic anal fissure(CAF)with internal anal sphincter(IAS)hypertonia,but it is burdened by high-risk postoperative faecal incontinence(FI).Sphincter saving procedures have recently been reconsidered as treatments to overcome this risk.The most employed procedure is fissurectomy with anoplasty,eventually associated with pharmacological sphincterotomy.AIM To evaluate whether fissurectomy and anoplasty with botulinum toxin injection improves the results of fissurectomy and anoplasty alone.METHODS We conducted a case-control study involving 30 male patients affected by CAF with hypertonic IAS who underwent fissurectomy and anoplasty with V-Y cutaneous flap advancement.The patients were divided into two groups:Those in group I underwent surgery alone,and those in group II underwent surgery and a botulinum toxin injection directly into the IAS.They were followed up for at least 2 years.The goals were to achieve complete healing of the patient and to assess the FI and recurrence rate along with manometry parameters.RESULTS The intensity and duration of post-defecatory pain decreased significantly in both groups of patients starting with the first defecation,and this reduction was higher in group II.Forty days after surgery,we achieved complete wound healing in all the patients in group II but only in 80%of the patients in group I(P<0.032).We recorded 2 cases of recurrence,one in each group,and both healed with conservative therapy.We recorded one temporary and low-grade postoperative case of“de novo”FI.Manometry parameters reverted to the normal range earlier for group II patients.CONCLUSION The injection of botulinum toxin A in association with fissurectomy and anoplasty with a V-Y advancement flap improves the results of surgery alone in patients affected by CAF with IAS hypertonia.	Beatrice D'Orazio Girolamo Geraci Fausto Famà Gloria Terranova Gaetano Di Vita	2021	World Journal of Clinical Cases2021，9，32：	2
2	Acute gouty synovitis associated with 'urate milk' 显示文摘	FAM A G REIS M D SZALAI J P	1997	J Rheumatol1997，24，12：	1
3	Long-chain polyunsaturated fatty acids in the growth and development of the Brainand memory 显示文摘	DAS U N FAMS M D	2003	Nutrition2003，19，：	1
4	Nutritional factors in the pathobiology of human essential hypertension 显示文摘	Undurti N D Fams M D	2001	Nutrition2001，17，4：	1
5	Long-chain polyunsaturated fatty acids in the growth and development of the brain and memory显示文摘	Das U N Fams M D	2003	Nutrition2003，19，：	1
6	Performance of concrete beams reinforced with basalt FRP for flexure and shear 显示文摘	Tomlinson D Fam A	2015	Journal of composites for construction2015，，：	1
7	Sequences of elongation factors-1α and-1γ andstimulation by juvenile hormone in Locusta migratoria显示文摘	ZHOU S ZHANG J FAM M D	2002	Insect Biochemistry and Molecular Biology2002，32，：	1
8	Trust and the online relationship:An exploratory study from New Zealand显示文摘	Fam K S Foscht T Collins R D	2004	Tourism Management2004，25，2：	1
9	Long-chain polyunsaturated fatty acids in the growth and development of the brain and memory 显示文摘	Das U N Fams M D	2003	Nutrition2003，19，：	1
10	Trust and the online relationship: An exploratory study from New Zealand 显示文摘	Fam K S Foscht T Collins R D	2004	Tourism Management2004，25，2：	1
11	Rectangular Filament Wound Glass Fiber Reinforced Polymer Tubes Filled with Concrete Under Flexural and Axial Loading:Experimental Investigation显示文摘	FAM A SCHNERCH D RIZKALLA S	2005	Journal of Composites for Construction2005，9，1：	1
12	Rectangular Filament Wound Glass Fiber Reinforced Polymer Tubes Filled with Concrete Under Flexural and Axial Loading:Analytical Modeling显示文摘	FAM A SCHNERCH D RIZKALLA S	2005	Journal of Composites for Construction2005，9，1：	1
13	The Influence of Reli- gion on Aittudes towards the Advertising of Controversial Products 显示文摘	Fam K S Waller D S Erdogan B Z	2004	European Journal of Marketing2004，38，56：	1
14	Fluorodeoxyglueose positron emission tomography in semantic dementia after 6 months of memantine: an open-label pilot study 显示文摘	Chow TW Fam D Graff-Guen'ero A	2013	Int J Geriatr Psychiatry2013，28，：	1
15	Trust and the online relationship:An exploratory study from New Zealand显示文摘	Fam K S Foscht T Collins R D	2004	Tourism Management2004，25，2：	1
16	Estrogen,statins,and polyunsaturated fatty acids:similarities in their actions and denefits is there a common link显示文摘	Das U N Fams M D	2002	Nutrition2002，18，：	1
17	Novel felt pseudocapacitor based on carbon nanotube/metal oxides显示文摘	Fam D W H Azoubel S Liu L	2015	Journal of Materials Science2015，50，20：	1
18	The isoprostanes: unique products of arachidonic acid oxidation - A review 显示文摘	Fam S S Morrow J D	2003	Curr Med Chem2003，10，：	1
19	Computed tomography in the diagnosis of early ankylosing spondylitis显示文摘	Fam A G Rumenstein J D Chin-Sang H		0，，08：	1
20	Rectangular filamentwound glass fiber reinforced polymer tubes filled with concrete under flexural and axial loading:Experimental investigation显示文摘	Fam A Schnerch D Rizkalla S	2005	Journal of Composites for Construction2005，9，1：	1

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