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| 1 | Sm-Nd isotopic age and genesis of gabbro xenoliths in Daoxian County, Hunan Province显示文摘MANY geologists pay attention to Mesozoic tectonomagmatic activity and the associating multi-metal ore deposits in South China. However, the age of the transformatiori of tectonic regimein the area is little studied. Occurrence of gabbro xenoliths in Mesozoic alkaline basalts inDaoxian region, Hunan Province, shows that the lithosphere in the region was intensely ex-tended and thinned during the Mesozoic, followed by underplating of mantle-derived mag- | Guo, F Fan, WM Lin, G Lin, YX | 1997 | Chinese Science Bulletin1997，42，21： | 14 |
| 2 | Identification of tumor associated single-chain Fv by panning and screening antibody phage library using tumor cells显示文摘AIM:To study the feasibility of panning and screeningphage-displaying recombinant single-chain variablefragment (ScFv) of anti-tumor monoclonal antibodiesfor fixed whole cells as the carriers of mAb-bindingantigens.ME,ODS: The recombinant phage displaying librariesfor anti-colorectal tumor mAb MC3Ab, MC5Ab andanti-gastric tumor mAb MGD1 was constructed.Panning and screening were carried outby means ofmodified fixation of colorectal and gastric tumor cellsexpressed the mAb-binding antigens. Concordance ofbinding specificity to tumor cells between phageclones and parent antibodies was analyzed. Thephage of positive clones was identified withcompetitive ELISA, and infected by E.coli HB2151 toexpress soluble ScFv.RESULTS:The ratio of positive clones to MC3-ScF-MC5-ScFv and MGD1-ScFv were 60 %, 24 % and 30 %. MC3-ScFv had Mr 32 000 confirmed by Western blot. Thespecificity to antigen had no difference between 4positive recombinant phage antibodies and MC3Ab.CONCLUSION:The modified process of fixing wholetumor cells is efficient, convenient and feasible to panand screen the phage-displaying ScFv of anti-tumormonoclonal antibodies. | Nie, YZ He, FT Li, ZK Wu, KC Cao, YX Chen, BJ Fan, DM | 2002 | World Journal of Gastroenterology2002，8，4： | 12 |
| 3 | Experimental study on antiatherosele rotic treatmenlby PGE1 combined with vitamine and estradiol显示文摘 | Qiu JM Gao YX Fan YC | 1995 | Chin Med J Engl1995，108，1： | 1 |
| 4 | The muhisubstrate adapter Gab1 regulates hepatocyte growth factor ( scatter factor) - c - Met sig- naling for cell survival and DNA repair 显示文摘 | Fan S Ma YX Gao M | 2001 | Mol Cell Biol2001，21，15： | 1 |
| 5 | The multisuhstrate adapter Gab1 regulates hepatoeyte growth factor (scatter factor)-cMet signaling for cell survival and DNA repair显示文摘 | FAN S MA YX GAO M | 2001 | Mol Cell Biol2001，21，15： | 1 |
| 6 | Blumea balsamifera-A Phytochemical and Pharmacological Review显示文摘 | Pang YX Wang D Fan ZW | 2014 | Molecules2014，19，： | 1 |
| 7 | Expression and prognostic roles of TRPV5 and TRPV6in non-small cell lung cancer after curative resection显示文摘 | Fan H Shen YX Yuan YF | 2014 | Asian Pac J Cancer Prev2014，15，6： | 1 |
| 8 | p300 modulates the BRCA1 inhibition of estrogen receptor activity显示文摘 | Fan S Ma YX Wang C | 2002 | Cancer Res2002，62，1： | 1 |
| 9 | Role of direct interaction in BRCA1 inhibition of estrogen receptor activity 显示文摘 | Fan S Ma YX Wang C | 2001 | Oncogene2001，20，1： | 1 |
| 10 | The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair 显示文摘 | Fan S Ma YX Gao M | 2001 | Mol Cell Biol2001，21，15： | 1 |
| 11 | Oxymatrine inhibits collagen synthesis in keloid fibroblasts via inhibition of transforming growth factor-β1/Smad signaling pathway 显示文摘 | Fan DL Zhao WJ Wang YX | 2012 | Int J Dermatol2012，51，： | 1 |
| 12 | Oxymatrine inhibits collagen synthesis in keloid fibroblasts via inhibition of transforming growth faetor-IM/Smad signaling pathway 显示文摘 | Fan DL Zhao WJ Wang YX | 2012 | Int J Dermatol2012，51，4： | 1 |
| 13 | BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha显示文摘 | Ma YX Fan SJ Hu CY | | 0，，01： | 1 |
| 14 | Role of direct interaction in BRCA1 inhibition of estrogen receptor activity显示文摘 | Fan S Ma YX Wang C | 2001 | Oncogene2001，20，1： | 1 |
| 15 | p300 modulates the BRCA1 inhibition of estrogen receptor activity显示文摘 | Fan S Ma YX Wang C | 2002 | Cancer Res2002，62，1： | 1 |
| 16 | Randomized trial of three phototherapy methods for the treatment of acne vulgarls in Chinese patients 显示文摘 | Liu LH Fan X An YX | 2014 | Photodermatol Photoimmunol Photomed2014，30，5： | 1 |
| 17 | Electron theory analysis on formation of spheroidal carbide in vanadium-alloyed white cast iron显示文摘THE brittleness of abrasion-resistant plain white cast iron has strongly hindered its wider application so far. In order to solve this problem, many researchers have made strenuous efforts to spheroidize the carbide in white cast iron. By alloying and inoculating the liquid white cast | Ye, YF Fan, TX Shang, YX | 1997 | Chinese Science Bulletin1997，42，7： | 1 |
| 18 | On-line prediction of fresh pork quality using visible/near-infrared reflectance spectroscopy显示文摘 | Liao YT Fan YX Cheng F | | 0，，04： | 1 |
| 19 | Nitrogen dynamics differed among the first six root branch orders of Fraxinus mandshurica and Larix gmelinii during short-term decomposition 显示文摘 | Fan PP Jiang YX | 2010 | J Plant Res2010，123，： | 1 |
| 20 | Guanidine hydrochloride exerts dual effects on the tryptophan synthase alpha 2 bate 2 complex as a cation activator and as a modulator of the active site conformation 显示文摘 | Fan YX McPehie P Miles EW | 1999 | Biochemistry1999，38，24： | 1 |
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