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| 1 | Growth of ZnO self-converted 2D nanosheet zeolitic imidazolate framework membranes by an ammoniaassisted strategy显示文摘塑造象金属那样的水晶的多孔的材料器官的框架(MOF ) 和沸石进二维(2D ) nanosheet 形成为开发高效的分子的 sieving 膜是高度合乎需要的。然而,常规脱落免职为 nanosheet MOF 管状的膜的大规模制造复杂、挑战性。第一次,这里,我们由 ZnO 自我变换和氨帮助报导一种直接生长技术制作 zeolitic imidazolate 框架(ZIF ) 膜在多孔的空纤维底层上由 2D nanosheets 组成;膜对大规模工业煤气的分离过程合适。为 ZIF nanosheet 膜的建议制造过程在作为一个调节的人包含铵氢氧化物的一个 ligand 答案基于 ZnO 的预先扔的薄层的局部性的自我变换。产生 ZIF 2D nanosheet 管状的膜是高度面向的并且仅仅在厚度的 50 nm。它展出优秀分子的 sieving 性能,与为 H 2/CO2 分离的高 H 2 渗入和选择。这种技术为大规模分子的 sieving 应用在 MOF nanosheet 膜制造显示出大诺言。 | Yujia Li Lu Lin Min Tu Pei Nian Ashlee J. Howarth Omar K. Farha Jieshan Qiu Xiongfu Zhang | 2018 | Nano Research2018，11，4： | 6 |
| 2 | Antineoplastic effects of deoxyelephantopin,a sesquiterpene lactone from Elephantopusscaber, on lung adenocarcinoma (A549) cells显示文摘OBJECTIVE: Deoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber, showed inhibition of the growth of various tumor cells in vitro. In the present study, we investigated the cytotoxicity and apoptosis-inducing capacity of deoxyelephantopin on lung adenocarcinoma (A549) cells. METHODS: The cytotoxic effect of deoxyelephantopin on A549 cells and normal lymphocytes was evaluated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and 50% inhibitory concentration (IC50) value was determined. The self-renewal and proliferating potential of A549 cells after treatment with deoxyelephantopin were examined by colony formation assay. Cellular morphology of deoxyelephantopin-treated cells was observed using phasecontrast microscopy. The induction of apoptosis was evaluated using acridine orange and ethidium bromide staining, Hoechst 33342 staining, terminal deoxynucleotidyl transferase-mediated dUTP biotin nick end-labeling (TUNEL) assay, DNA fragmentation analysis and Annexin V-fluorescein isothiocyanate staining by flow cytometry. Activation of caspases was detected using fluorogenic substrate specific to caspases 2, 3, 8 and 9 and flow cytometric analysis. The total cellular DNA content and expression of cleaved poly (ADP-ribose) polymerase was also analyzed. RESULTS: Deoxyelephantopin exhibited cytotoxicity to A549 cells (IC50=12.287 μg/mL), however, there was no toxicity towards normal human lymphocytes. Deoxyelephantopin suppressed the colony-forming ability of A549 cells in a dose-dependent manner. Acridine orange, ethidium bromide and Hoechst 33342 staining showed cell shrinkage, chromosomal condensation and nuclear fragmentation, indicating induction of apoptosis. Deoxyelephantopin increased apoptosis of A549 cells, as evidenced by more TUNEL-positive cells. DNA fragmentation and Annexin V staining revealed late-stage apoptotic cell population. Deoxyelephantopin inhibited A549 cell growth by cell cycle arrest at G2/M phase and induced apoptosis through both extrinsic and intrinsic pathways. CONCLUSION: These results suggest that deoxyelephantopin has great potential as a new chemotherapeutic agent to be developed further for the treatment of lung cancer. | Farha A. Kabeer Geetha B. Sreedevi Mangalam S. Nair Dhanya S. Rajalekshmi LathaP. Gopalakrishnan Sujathan Kunjuraman Remani Prathapan | 2013 | Journal of Integrative Medicine2013，11，4： | 4 |
| 3 | Security and privacy issues of physical objects in the IoT:Challenges and opportunities显示文摘In the Internet of Things(IoT),security and privacy issues of physical objects are crucial to the related applications.In order to clarify the complicated security and privacy issues,the life cycle of a physical object is divided into three stages of pre-working,in-working,and post-working.On this basis,a physical object-based security architecture for the IoT is put forward.According to the security architecture,security and privacy requirements and related protecting technologies for physical objects in different working stages are analyzed in detail.Considering the development of IoT technologies,potential security and privacy challenges that IoT objects may face in the pervasive computing environment are summarized.At the same time,possible directions for dealing with these challenges are also pointed out. | Xuanxia Yao Fadi Farha Rongyang Li Ismini Psychoul Liming Chen Huansheng Ning | 2021 | Digital Communications and Networks2021，7，3： | 3 |
| 4 | Convergence of computing,communication,and caching in internet of things显示文摘Internet of Things(IoTs)is a big world of connected objects,including the small and low-resources devices,like sensors,as well as the full-functional computing devices,such as servers and routers in the core network.With the emerging of new IoT-based applications,such as smart transportation,smart agriculture,healthcare,and others,there is a need for making great efforts to achieve a balance in using the IoT resources,including Computing,Communication,and Caching.This paper provides an overview of the convergence of Computing,Communication,and Caching(CCC)by covering the IoT technology trends.At first,we give a snapshot of technology trends in communication,computing,and caching.As well,we describe the convergence in sensors,devices,and gateways.Addressing the aspect of convergence,we discuss the relationship between CCC technologies in collecting,indexing,processing,and storing data in IoT.Also,we introduce the three dimensions of the IoTs based on CCC.We explore different existing technologies that help to solve bottlenecks caused by a large number of physical devices in IoT.Finally,we propose future research directions and open problems in the convergence of communication,computing,and cashing with sensing and actuating devices. | Mohammed Amine Bouras Fadi Farha Huansheng Ning | 2020 | Intelligent and Converged Networks2020，1，1： | 2 |
| 5 | Access Control and Authorization in Smart Homes: A Survey显示文摘With the rapid development of cyberspace and smart home technology, human life is changing to a new virtual dimension with several promises for improving its quality. Moreover, the heterogeneous, dynamic, and internet-connected nature of smart homes brings many privacy and security difficulties. Unauthorized access to the smart home system is one of the most harmful actions and can cause several trust problems and relationship conflicts between family members and invoke home privacy issues. Access control is one of the best solutions for handling this threat, and it has been used to protect smart homes and other Internet of Things domains for many years. This survey reviews existing access control schemes for smart homes, which concern the essential authorization requirements and challenges that need to be considered while designing an authorization framework for smart homes. Furthermore, we note the most critical challenges that other access control solutions neglect for smart homes. | Ziarmal Nazar Mohammad Fadi Farha Adnan O.M Abuassba Shunkun Yang Fang Zhou | 2021 | Tsinghua Science and Technology2021，26，6： | 2 |
| 6 | Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities显示文摘 | Farha S Asosingh K Xu W | 2011 | Blood2011，117，： | 1 |
| 7 | Gas-sorp- tion properties of cobalt (II)-carborane-based coordination poly- mers as a function of morphology 显示文摘 | FARHA O K SPOKOYNY A M MULFORT K L | 2009 | Small2009，5，15： | 1 |
| 8 | De novo synthesis of a metal-organic framework material featuring ultrahigh surface area and gas storage capacities 显示文摘 | Farha O K Yazaydiin A O Eryazici I et at | 2010 | Nature Chemistry2010，2，： | 1 |
| 9 | De novo synthesis of a metal-organic framework material featuring ultrahigh surface area and gas storage capacities显示文摘 | Farha O K Yazaydin A O Eryazici I | 2010 | Nat Chem2010，2，： | 1 |
| 10 | Macrophage migration inhibitory factor, Toll-like receptor 4, and CD14 polymorphisms with altered expression levels in patients with ulcerative colitis显示文摘 | Gunisetty Sivaram Santosh K. Tiwari Avinash Bardia Farha Anjum Satti Vishnupriya Aejaz Habeeb Aleem A. Khan | 2012 | Human Immunology2012，，2： | 1 |
| 11 | 显示文摘 | SHULTZ A M FARHA O K HUPP J T | 2009 | J Am Chem Soc2009，131，： | 1 |
| 12 | Post-synthesis alkoxide formation within metal-organic framework materials: A strategy for incorporating highly coordinatively unsaturated metal ions 显示文摘 | Mullort K L Farha O K Stern C L | 2009 | J Am Chem Soc2009，131，11： | 1 |
| 13 | Functional polymorphisms in XRCC - 1 and APE - 1 contribute to increased apoptosis and risk of ulcerative colitis显示文摘 | Avinash Bardia Santosh K. Tiwari Sivaram Gunisetty Farha Anjum Pratibha Nallari Md. Aejaz Habeeb Aleem A. Khan | 2012 | Inflammation Research2012，，4： | 1 |
| 14 | Metal-organic framework materials with ultrahigh surface areas: is the sky the limit?显示文摘 | Farha Omar K Eryazici Ibrahim Jeong Nak Cheon Hauser Brad G Wilmer Christopher E Sarjeant Amy A Snurr Randall Q Nguyen SonBinh T Ozgox Yazaythn A Hupp Joseph T | 2012 | Journal of the American Chemical Society2012，134，15： | 1 |
| 15 | Rapid HCV -RNA decline with once daily TMC435: a phase I study in healthy volunteers and hepatitis C patients显示文摘 | Reesink HW Fanning GC Farha KA | 2010 | Gastroenterology2010，138，3： | 1 |
| 16 | Selective bifunctional modification of a non-catenated metal-organic framework material via 'click' chemistry显示文摘 | Gadzikwa T Farha O K Malliakas C D | 2009 | Journal of the American Chemical Society2009，131，13： | 1 |
| 17 | Drying kinetics and characteristic drying curve of lightly salted sardine(Sardinella aurita)显示文摘 | BELLAGHA S AMAMI E FARHA A | 2002 | Drying Technology2002，20，7： | 1 |
| 18 | Metal-organic framework materials as chemical sensors显示文摘 | Kreno L E Leong K Farha O K | 2012 | Chem Rev2012，112，2： | 1 |
| 19 | Rational design, synthesis, purification, and activation of metal organic framework materials 显示文摘 | FARHA O K HUPP J T | 2010 | Accounts of Chemical Research2010，43，8： | 1 |
| 20 | Mast cell number, phenotype, and function in human pulmonary arterial hy- pertension显示文摘 | Farha S Sharp J Asosingh K | 2012 | Pulm Circ2012，2，2： | 1 |
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