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| 1 | Dependence of dynamic contour and Goldmann applanation tonometries on peripheral corneal thickness显示文摘AIM:To determine the effects of peripheral corneal thickness(PCT) on dynamic contour tonometry(DCT) and Goldmann applanation tonometry(GAT).METHODS:A cross-sectional study.We created a software which calculates the corneal contour(CC) as a function of the radius from the corneal apex to each pixel of the contour.The software generates a central circumference with a radius of 1 mm and the remainder of the cornea is segmented in 5 rings concentric with corneal apex being its diameter not constant around the corneal circumference as a consequence of the irregular CC but keeping constant the diameter of each ring in each direction of the contour.PCT was determined as the mean thickness of the most eccentric ring.Locally weighted scatterplot smoothing(LOWESS) regression was used to determine the pattern of the relationship between PCT and both DCT and GAT respectively.Thereafter,two multivariable linear regression models were constructed.In each of them,the dependant variable was intraocular pressure(IOP) as determined using GAT and DCT respectively.In both of the models the predictive variable was PCT though LOWESS regression pattern was used to model the relationship between the dependant variables and the predictor one.Age and sex were also introduced control variables along with their first-degree interactions with PCT.Main outcome measures include amount of IOP variation explained through regression models(R2) and regression coefficients(B).RESULTS:Subjects included 109 eyes of 109 healthy individuals.LOWESS regression suggested that a 2 nd-degree polynomial would be suitable to model the relationship between both DCT and GAT with PCT.Hence PCT was introduced in both models as a linear and quadratic term.Neither age nor sex nor interactions were statistically significant in both models.For GAT model,R2 was 17.14%(F=9.02;P=0.0002),PCT linear term B was-1.163(95% CI:-1.163,-0.617).PCT quadratic term B was 0.00081(95% CI:0.00043,0.00118).For DCT model R2 was 14.28%(F=9.29;P=0.0002),PCT linear term B was-0.712(95% CI:-1.052,-0.372),PCT quadratic term was B=0.0005(95% CI:0.0003,0.0007).CONCLUSION:DCT and GAT measurements are conditioned by PCT though this effect,rather than linear,follows a 2^(nd)-degree polynomial pattern. | Federico Saenz-Frances Claudia Sanz-Pozo Lara Borrego-Sanz Luis Ja?ez Laura MoralesFernandez Jose Maria Martinez-de-la-Casa Julian Garcia-Sanchez Julian Garcia-Feijoo Enrique Santos-Bueso | 2017 | International Journal of Ophthalmology(English edition)2017，10，10： | 1 |
| 2 | Effect of Corneal Morphometry on Dynamic Contour and Goldmann Applanation Tonometry显示文摘 | Federico Saenz-Frances Luis Ja?ez Lara Borrego-Sanz Jose Maria Martinez-de-la-Casa Maria Jerez-Fidalgo Julian Garcia-Sánchez Julian Garcia-Feijoo | 2013 | Journal of Glaucoma2013，，5： | 1 |
| 3 | Pulmonary resection for lung Cancer in octogenarians显示文摘 | Pagni S Federico JA Ponn RB | 1997 | Ann Thorac Sury1997，63，： | 1 |
| 4 | Pulmonary resection for lung cancer in octogenarians显示文摘 | Pagni S Federico JA Pann RB | 1997 | Ann Thorac Surg1997，63，： | 1 |
| 5 | Pulmonary resection for lung cancer in octogenarians 显示文摘 | Pagni S Federico JA Pann RB | 1997 | Ann Thorac Surg1997，63，3： | 1 |
| 6 | Outpatient chest tube management 显示文摘 | Ponn RB Silverman HJ Federico JA | 1997 | Ann Thorac Surg1997，64，5： | 1 |
| 7 | Prevention of delayed gastric emptying after esophagectorny: a single centerrs experience with botulinum toxin显示文摘 | Martin JT Federico JA McKelvey AA | 2009 | Ann Thorac Surg2009，87，6： | 1 |
| 8 | Pulmonary resection for lung cancer in octogenarians显示文摘 | Pagni S Federico JA Pann RB | 1997 | Ann Thorac Surg1997，63，： | 1 |
| 9 | Anatomical characterization of central, apical and minimal corneal thickness显示文摘·AIM: To anatomically locate the points of minimum corneal thickness and central corneal thickness(pupil center) in relation to the corneal apex.·METHODS: Observational, cross-sectional study, 299 healthy volunteers. Thickness at the corneal apex(AT),minimum corneal thickness(MT) and corneal thickness at the pupil center(PT) were determined using the pentacam. Distances from the corneal apex to MT(MD)and PT(PD) were calculated and their quadrant position(taking the corneal apex as the reference) determined:point of minimum thickness(MC) and point of central thickness(PC) depending on the quadrant position. Two multivariate linear regression models were constructed to examine the influence of age, gender, power of the flattest and steepest corneal axes, position of the flattest axis, corneal volume(determined using the Pentacam)and PT on MD and PD. The effects of these variables on MC and PC were also determined in two multinomial regression models.·RESULTS: MT was located at a mean distance of 0.909 mm from the apex(79.4% in the inferior-temporal quadrant). PT was located at a mean distance of 0.156 mm from the apex. The linear regression model for MD indicated it was significantly influenced by corneal volume(B =-0.024; 95% CI:-0.043 to-0.004). No significant relations were identified in the linear regression model for PD or the multinomial logisticregressions for MC and PC.·CONCLUSION: MT was typically located at the inferiortemporal quadrant of the cornea and its distance to the corneal apex tended to decrease with the increment of corneal volume. | Federico Saenz-Frances Martha Cecilia Bermúdez-Vallecilla Lara Borrego-Sanz Luis Jaez J osé Marìa Martinez-de-la-Casa Laura Morales-Fernandez Enrique Santos-Bueso Julián Garcia-Sanchez Julián Garcia-Feijoo | 2014 | International Journal of Ophthalmology(English edition)2014，7，4： | 0 |
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