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36篇 您的检索式:作者名="Feliz"
    题名 作者 年代 出处 被引量
1Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel 2014World Journal of Gastroenterology2014,20,42:5
2Pedestrian tracking using inertial sensors显示文摘R Feliz E Zalama J G Garcia-Bermejo 0,,:1
3Positive Homoclinic Solutions for a Class of Second Order Differential Equations显示文摘 Minhós Feliz Stepan Tersian 1999J Math Anal Appl1999,240,1:1
4Dramatic change in Citrus tristeza virus populations in the Dominican Republic显示文摘MATOS L A HILF M E CAYETANO X A FELIZ A O HARPER S J FOLIMONOVA S Y 2013Plant Disease2013,97,:1
5Malaysiatin, the first cyclic heptapeptide from a marine sponge 显示文摘Fernandez R Omar S Feliz M 1992Tetrahedrom Lett1992,33,:1
6Diagnostic and therapeutic laparoscopy in pediatric abdominal trauma显示文摘Feliz A Sultz B Mckenna C 2006J Pediatr Surg2006,41,1:1
7Common face 显示文摘FELIZ E 2012Avio- nics Magazine2012,,3:1
8Minimally invasive repair of pectus excavatum in adult patients显示文摘Hebra A Jacobs JP Feliz A 2006Am Surg2006,72,9:1
9Diagnostic and therapeutic laparoscopy in pediatric abdominal trauma 显示文摘Feliz A Shultz B McKenna C 2006J Pediatr Surg2006,41,4:1
10Imidazolium carboxylates as versatile and selective N-heterocyclic carbene transfer agents: synthesis, mechanism, and applications 显示文摘Voutchkova A M Feliz M Clot E 2007J Am Chem Soc2007,129,12:1
11A patient - doctor relationship questionnaire ( PDRQ - 9 ) in primary care: development and psychometric evaluation 显示文摘Van der Feliz - Comelis CM Van Oppen P Van Marwijk 2004Gen Hosp Psychiatry2004,26,3:1
12Minimally invasive repair of pee- tus excavatum in adult patients显示文摘Hebra A Jacobs J P Feliz A 2006Am Surg2006,72,9:1
13Pedestrian tracking using inertial sensors显示文摘Feliz R Zalama E 2009Journal of Physical Agents2009,,3:1
14Factors associated with the successful aging of the sociallyactive elderly in the metropolitan region of Porto Alegre显示文摘Joao Feliz Duarte de Moraes Valdemarina Bidone de Azevedoe Souza 2005Rev Bras Psiquiatr2005,27,4:1
15Application of a hybrid case-based reasoning approach in electroplating industry 显示文摘Feliz T S Chan 2005Expert Systems2005,,29:1
16Outcome of patients treated with palliative weekly Paclitaxel plus Cetuximab in recurrent head and neck cancer after failure of platinum-based therapy显示文摘Sosa AE Grau JJ Feliz L 2014Eur Arc Otorhinolaryngo[2014,271,2:1
17Anti-vascular endothelial growth factortherapy in the era of personalized medicine显示文摘Feliz LR Tsimberidou AM 2013Cancer Chemotherapy Pharmacology2013,72,1:1
18Steam-Explosion Pretreatment of Olive Cake显示文摘B Feliz 6 n J Fern 6 ndez-Bolafios A Heredia 2000JAOCS2000,77,1:1
19查看详情显示文摘Forment-Aliaga A Coronado E Feliz M Gaita-Arif A. Llusar R. Romero E M 0,,:1
20Aliphatic versus aromatic C-H activation in the formation of abnormal carbenes with iridium: a combined experimental and theoretical study 显示文摘Viciano M Feliz M Corber 2007Organometallics2007,26,:1
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