|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Mechanism underlying treatment of ischemic stroke using acupuncture:transmission and regulation显示文摘The inflammatory response after cerebral ischemia/reperfusion is an important cause of neurological damage and repair.After cerebral ischemia/reperfusion,microglia are activated,and a large number of circulating inflammatory cells infiltrate the affected area.This leads to the secretion of inflammatory mediators and an inflammatory cascade that eventually causes secondary brain damage,including neuron necrosis,blood-brain barrier destruction,cerebral edema,and an oxidative stress response.Activation of inflammatory signaling pathways plays a key role in the pathological process of ischemic stroke.Increasing evidence suggests that acupuncture can reduce the inflammatory response after cerebral ischemia/reperfusion and promote repair of the injured nervous system.Acupuncture can not only inhibit the activation and infiltration of inflammatory cells,but can also regulate the expression of inflammation-related cytokines,balance the effects of pro-inflammatory and anti-inflammatory factors,and interfere with inflammatory signaling pathways.Therefore,it is important to study the transmission and regulatory mechanism of inflammatory signaling pathways after acupuncture treatment for cerebral ischemia/reperfusion injury to provide a theoretical basis for clinical treatment of this type of injury using acupuncture.Our review summarizes the overall conditions of inflammatory cells,mediators,and pathways after cerebral ischemia/reperfusion,and discusses the possible synergistic intervention of acupuncture in the inflammatory signaling pathway network to provide a foundation to explore the multiple molecular mechanisms by which acupuncture promotes nerve function restoration. | Bing-Qian Cao Feng Tan Jie Zhan Peng-Hui Lai | 2021 | Neural Regeneration Research2021，16，5： | 43 |
| 2 | Insult of gastroesophageal reflux on airway: clinical significance of pharyngeal nozzle显示文摘在到最糟的最高的注意在航线上吸烟以及薄雾侮辱的全球付钱的时间,所有人知道两个外长、显著。然而,包括许多医药人员,人们主要不知道 gastroesophageal 倒流(GER ) 怎么糟糕在我们的自己的航线上侮辱。GER 的症状通常被看作心痛和流回,它能主要被容忍。不管多么起来在它出现的地方,去的胃的内容相对地传递食管然后远侧的咽象苛评一样的鸟喙,用作一张嘴,以便生产众多微粒子并且到达oro鼻的洞并且另外引起的航线过敏鼻炎和气喘的攻击,甚至肺的实质损害。它将减少生活质量或甚至使受危险生活。内长的侮辱在呼吸系统出现,但是从消化的道发源的点不是众所周知的并且经常 undiagnosed 并且不正确地对待。导致的航线挑战是的 GER 一个可对待、预防的实体一旦诊断被做,好消除能通过 radiofrequency 或 fundoplication 借助于张开的贲门的生活方式调整,药,或固定被期望。作者王忠高博士承受了它为长并且症状在反倒流外科以后消失了 8 年。这是王忠高博士和他的队工作的一个演讲并且将引起注意到公众以便认出作为吸烟或薄雾从人的本身,然而并非从外面的环境发生的一个可对待的条件做的这个相对未知的实体。 | Zhonggao Wang Zhiwei Hu Jimin Wu Feng Ji Hongtao Wang Yungang Lai Xiang Gao Yachan Ning Chengchao Zhang Zhitong Li Weitao Liang Jianjun Liu | 2015 | Frontiers of Medicine2015，9，1： | 21 |
| 3 | FUSAR-Ship:building a high-resolution SAR-AIS matchup dataset of Gaofen-3 for ship detection and recognition显示文摘Gaofen-3 (GF-3) is China's first civil C-band fully polarimetric spaceborne synthetic aperture radar (SAR) primarily missioned for ocean remote sensing and marine monitoring. This paper proposes an automatic sea segmentation, ship detection, and SAR-AIS matchup procedure and an extensible marine target taxonomy of 15 primary ship categories, 98 sub-categories, and many non-ship targets. The FUSAR-Ship high-resolution GF-3 SAR dataset is constructed by running the procedure on a total of 126 GF-3 scenes covering a large variety of sea, land, coast, river and island scenarios. It includes more than 5000 ship chips with AIS messages as well as samples of strong scatterer, bridge, coastal land, islands, sea and land clutter. FUSAR-Ship is intended as an open benchmark dataset for ship and marine target detection and recognition. A preliminary 8-type ship classification experiment based on convolutional neural networks demonstrated that an average of 79% test accuracy can be achieved. | Xiyue HOU Wei AO Qian SONG Jian LAI Haipeng WANG Feng XU | 2020 | Science China(Information Sciences)2020，63，4： | 19 |
| 4 | Efficacy of Real-world Entecavir Therapy in Treatment-naive Chronic Hepatitis B Patients显示文摘 | Yan-Di Xie Hui Ma Bo Feng Lai Wei | 2017 | Chinese Medical Journal2017，，18： | 16 |
| 5 | P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte- endothelial adhesion and promotes neurovascular injury during septic encephalopathy显示文摘 | Huan Wang Ling-Juan Hong Ji-Yun Huang Quan Jiang Rong-Rong Tao Chao Tan Nan-Nan Lu Cheng-Kun Wang Muhammad M Ahmed Ying-Mei Lu Zhi-Rong Liu Wei-Xing Shi En-Yin Lai Christopher S Wilcox Feng Han | 2015 | Cell Research2015，25，6： | 16 |
| 6 | Preliminary study on assessment of nutrient transport in the Taihu Basin based on SWAT modeling显示文摘With the Taihu Basin as a study area, using the spatially distributed and mechanism-based SWAT model, preliminary simulations of nutrient transport in the Taihu Basin during the period of 1995~2002 has been carried out. The topography, soil, meteorology and land use with industrial point pollution discharge, the loss of agricultural fertilizers, urban sewerage, and livestock drainages were all considered in the boundary conditions of the simulations. The model was calibrated and validated against water quality monitoring data from 2001 to 2002. The results show that the annual total productions of nitrogen (TN) and phosphorus (TP) into Lake Taihu are 40000t and 2000t respectively. Nutrient from the Huxi Region is a major resource for Lake Taihu. The non-point source (surface source) pollution is the main form of catchment sources of nutrients into Lake Taihu,occupied TN 53% and TP 56% respectively. TN and TP nutrients from industrial point pollution discharge are 30% and 16%, and sewerage in both forms of point source and non-point source are TN 31% and TP 47%. Both the loss of agricultural fertilizers and livestock drainages from the catchment should be paid more attention as an important nutrient source. The results also show that SWAT is an effective model for the simulation of temporally and spatially nutrient changes and for the assessment of the trends in a catchment scale. | LAI Geying, YU Ge & GUI Feng Nanjing Institute of Geography & Limnology, Chinese Academy of Sciences, Nanjing 210008, China The Graduate School of the Chinese Academy of Sciences, Beijing 100039, China Key Lab of Poyang Lake Ecological Environment and Resource Development, Jiangxi Normal University, Nanchang 330027, China | 2006 | Science China Earth Sciences2006，49，z1： | 11 |
| 7 | Fixation of CO_2 by electrocatalytic reduction to synthesis of dimethyl carbonate in ionic liquid using effective silver-coated nanoporous copper composites显示文摘与高表面区域,开的孔和高效率,催化剂在 electrocatalytic 被准备并且第一采用了 CO2 的减小和 dimethyl 碳酸盐(直接数字控制) 的 electrosynthesis。为在离子的液体的 CO2 的 electrocatalytic 减小的电气化学的性质被周期的 voltammogram (CV ) 学习。象 electrocatalytic 性能上的温度,工作潜力和阴极材料一样的各种各样的反应变量的效果也被调查。直接数字控制的 80% 产量在最佳的反应条件下面被获得。 | Xuan Yun Wang Su Qin Liu Ke Long Huang Qiu Ju Feng De Lai Ye Bing Liu Jin Long Liu Guan Hua Jin | 2010 | Chinese Chemical Letters2010，21，8： | 10 |
| 8 | Clinical and experimental study of effect of Raondix Salviae Militiorhiza and other blood-activating and stasis-eliminating Chinese herbson hemodynamics of portal hypertension显示文摘INTRODUCTIONTherehasbeennolonglastingandsideeffectsfreedrugstolowertheportalhypertensioninpatientswithlivercirrhosissofar.Th... | YAO Xi Xian, CUI Dong Lai, SUN Yu Feng and LI Xiao Tian | 1998 | World Journal of Gastroenterology1998，4，5： | 10 |
| 9 | Enhanced high-temperature performance of Li-rich layered oxide via surface heterophase coating显示文摘Li-rich layered oxides have become one of the most concerned cathode materials for high-energy lithiumion batteries, but they still suffer from poor cycling stability and detrimental voltage decay, especially at elevated temperature. Herein, we proposed a surface heterophase coating engineering based on amorphous/crystalline Li3 PO4 to address these issues for Li-rich layered oxides via a facile wet chemical method. The heterophase coating layer combines the advantages of physical barrier effect achieved by amorphous Li3 PO4 with facilitated Li+diffusion stemmed from crystalline Li3 PO4. Consequently, the modified Li(1.2) Ni(0.2) Mn(0.6) O2 delivers higher initial coulombic efficiency of 92% with enhanced cycling stability at 55 °C(192.9 mAh/g after 100 cycles at 1 C). More importantly, the intrinsic voltage decay has been inhibited as well, i.e. the average potential drop per cycle decreases from 5.96 mV to 2.99 mV. This surface heterophase coating engineering provides an effective strategy to enhance the high-temperature electrochemical performances of Li-rich layered oxides and guides the direction of surface modification strategies for cathode materials in the future. | Yuefeng Su Feiyu Yuan Lai Chen Yun Lu Jinyang Dong Youyou Fang Shi Chen Feng Wu | 2020 | Journal of Energy Chemistry2020，29，12： | 7 |
| 10 | Top coal flows in an excavation disturbed zone of high section top coal caving of an extremely steep and thick seam显示文摘与轻轻的剧降相比长墙的探穴,在为极其陡峭、厚的缝接的充分使机械化的最高煤的探穴的一张工作的脸的长度是短的,当它的水平节与增加高时生产。但是探穴比率是低的,在一些灾难的力量结果例如房顶下降,在煤气的累积导致的一张工作的脸和危险由最高的煤的本地、大的区域倒塌导致了它。在裂缝的发展以后并且煤身体变弱,极其陡峭的缝接的最高的煤(小粒的媒介) 的高、破节(超过 60 掳) 表演清除非线性的运动的特征。我们彻底地分析了地质的环境,挖掘的采矿条件扰乱了地区。从大规模 3D 为最高的煤鈥搘a ter 鈥揼a s 的模拟建模并且联合的一个物理实验基于结果,我们断定削弱的最高的煤能被认为是间断媒介。我们使用了一个粒子流动代码程序高比较并且分析移植进程和 30 m 的运动节在在 Weihuliang 煤矿极其陡峭的缝接变弱前后随着时间的过去超过煤。我们的模拟,实验和监视表演的结果水的那注射前并且预先切开爆炸改进探穴能力和对称的探穴,为大区域减轻空间动态倒塌超过煤,延长有害气体的迁居时间并且外面免除他们 mined 区域并且那么在采矿完成安全。 | Miao Shengjun Lai Xingping Cui Feng | 2011 | Mining Science and Technology2011，21，1： | 7 |
| 11 | U-Pb Zircon Age, Geochemical, and Sr-Nd-Pb Isotopic Constraints on the Age and Origin of Mafic Dykes from Eastern Shandong Province, Eastern China显示文摘U-Pb 锆石年龄, geochemical,和从东方山东省的 mafic 女同性恋的 Sr-Nd-Pb 同位素的数据,东方中国此处被报导。激光脱离诱导地联合了从调查 mafic 女同性恋的二件样品的 U-Pb 锆石分析产出一致年龄从 121.9 妈的血浆团 spectrometry (LA-ICP-MS )?????? 猠潨桳湯瑩捩吗? | LIU Shen HU Ruizhong FENG Caixia GAO Shan FENG Guangying LAI Shaocong QI Youqiang Ian M. COULSON YANG Yuhong YANG Chaogui TANG Liang | 2013 | Acta Geologica Sinica(English Edition)2013，87，4： | 7 |
| 12 | Characterizing the composition of intestinal microflora by 16S rRNA gene sequencing显示文摘BACKGROUND This study determined the composition and diversity of intestinal microflora in patients with colorectal adenoma(CRA),which may provide precedence for investigating the role of intestinal microflora in the pathogenesis of colorectal tumors,the composition of intestinal microflora closely related to CRA,and further validating the possibility of intestinal flora as a biomarker of CRA.AIM To study the relationship between intestinal microflora and CRA.METHODS This is a prospective control case study from October 2014 to June 2015 involving healthy volunteers and patients with advanced CRA.High-throughput sequencing and bioinformatics analysis were used to investigate the composition and diversity of intestinal microflora in 36 healthy subjects and 49 patients with advanced CRA.Endpoints measured were operational taxonomic units of intestinal flora,as well as their abundance and diversity(αandβtypes).RESULTS In this study,the age,gender,body mass index,as well as location between controls and patients had no significant differences.The mucosa-associated gut microbiota diversity and bacterial distribution in healthy controls and colorectal adenomas were similar.The operational taxonomic unit,abundance,andαandβdiversity were all reduced in patients with CRA compared to controls.At the phylum level,the composition of intestinal microflora was comparable between patients and controls,but the abundance of Proteobacteria was increased,and Firmicutes and Bacteroides were significantly decreased(P<0.05).The increase in Halomonadaceae and Shewanella algae,and reduction in Coprococcus and Bacteroides ovatus,could serve as biomarkers of CRA.High-throughput sequencing confirms the special characteristics and diversity of intestinal microflora in healthy controls and patients with CRA.CONCLUSION The diversity of intestinal microflora was decreased in patients with CRA.An increase in Halomonadaceae and Shewanella algae are markers of CRA. | Wen-Jia Wang You-Lian Zhou Jie He Zhi-Qiang Feng Long Zhang Xiao-Bo Lai Jun-Xiao Zhou Hong Wang | 2020 | World Journal of Gastroenterology2020，26，6： | 7 |
| 13 | Modeling and simulation of urea-water-solution droplet evaporation and thermolysis processes for SCR systems显示文摘A reliable mathematical model of urea-water-solution(UWS) droplet evaporation and thermolysis is developed.The well known Abramzon–Sirignano evaporation model is corrected by introducing an adjustment coefficient considering the different evaporation behaviors of UWS droplet at different ambient temperatures. A semidetailed kinetic scheme of urea thermolysis is developed based on Ebrahimian's work. Sequentially, the evaporation characteristics, decomposition efficiency of a single UWS droplet and deposit formation are simulated. As a result, the relation of evaporation time, relative velocity, exhaust temperature and droplet initial diameter is presented. Synchronously, it indicates that temperature is the decisive factor for urea thermolysis. Different temperatures result in different deposit components, and deposit yield is significantly influenced by temperature and decomposition time. The current work can provide guidance for designing urea injection strategy of SCR systems. | Xubo Gan Dongwei Yao Feng Wu Jiawei Dai Lai Wei Xingwen Li | 2016 | Chinese Journal of Chemical Engineering2016，24，8： | 7 |
| 14 | Effects of neuregulin-1 on autonomic nervous system remodeling post-myocardial infarction in a rat model显示文摘Sympathetic nerve and vagus nerve remodeling play an important part in cardiac function post-myocardial infarction(MI). Increasing evidence indicates that neuregulin-1(NRG-1) improves cardiac function following heart failure. Since its impact on cardiac function and neural remodeling post-MI is poorly understood, we aimed to investigate the role of NRG-1 in autonomic nervous system remodeling post-MI. Forty-five Sprague-Dawley rats were equally randomized into three groups: sham(with the left anterior descending coronary artery exposed but without ligation), MI(left anterior descending coronary artery ligation), and MI plus NRG-1(left anterior descending coronary artery ligation followed by intraperitoneal injection of NRG-1(10 μg/kg, once daily for 7 days)). At 4 weeks after MI, echocardiography was used to detect the rat cardiac function by measuring the left ventricular end-systolic inner diameter, left ventricular diastolic diameter, left ventricular end-systolic volume, left ventricular end-diastolic volume, left ventricular ejection fraction, and left ventricular fractional shortening. m RNA and protein expression levels of tyrosine hydroxylase, growth associated protein-43(neuronal specific protein), nerve growth factor, choline acetyltransferase(vagus nerve marker), and vesicular acetylcholine transporter(cardiac vagal nerve fiber marker) in ischemic myocardia were detected by real-time PCR and western blot assay to assess autonomous nervous remodeling. After MI, the rat cardiac function deteriorated significantly, and it was significantly improved after NRG-1 injection. Compared with the MI group, m RNA and protein levels of tyrosine hydroxylase and growth associated protein-43, as well as choline acetyltransferase m RNA level significantly decreased in the MI plus NRG-1 group, while m RNA and protein levels of nerve growth factor and vesicular acetylcholine transporters, as well as choline acetyltransferase protein level slightly decreased. Our results indicate that NRG-1 can improve cardiac function and regulate sympathetic and vagus nerve remodeling post-MI, thus reaching a new balance of the autonomic nervous system to protect the heart from injury. | Xin Lai Liang Zhong Hai-xia Fu Song Dang Xin Wang Ning Zhang Gao-ke Feng Zi-qiang Liu Xi Wang Long Wang | 2017 | Neural Regeneration Research2017，12，11： | 7 |
| 15 | Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation显示文摘 | Ming-chun Lai Zhe Yang Lin Zhou Qian-qian Zhu Hai-yang Xie Feng Zhang Li-ming Wu Lei-ming Chen Shu-sen Zheng | 2012 | Medical Oncology2012，，3： | 6 |
| 16 | Animal study for airway inflammation triggered by gastroesophageal reflux显示文摘有额外食道的症状的背景 Gastroesophageal 倒流疾病,特别那些与呼吸 istress 正在吸引越来越多的注意。相关机制仍然在争吵。工作的目的是探索 gastroesophageal reflux.Methods 触发的航线发炎十六只 Sprague-Dawley 老鼠被用作学习组并且 9 作为控制。在学习组,有塑造小号的远侧的结束的一个塑料扩展程序被插入到更低的食管扩大贲门,幽门被绑扎。0.1 mol/L 的一 ml 盐酸酸被注入胃,当简单剖腹术为控制动物被执行时。从二个组的所有动物被牺牲在操作以后的 24 个小时。然后,气管切开术被带, bronchoalveolar lavage 液体在所有动物是镇定的。在液体的房间 intedeukin ( IL )被认为并且铺平-5,-6,在它的 -8 与控制组,相比是 measured.Results 学习组介绍了航线发炎的嗜中性的 pattem 和 IL-5 的提高的集中,没有关于嗜曙红血球 count.Conclusion 的重要差别的-6, -8 gastroesophageal 被触发倒流的航线发炎被不同于由气喘引起了那的 neutrophilic 航线发炎描绘,并且提高了 IL-5 , -6 和-8, w | LAI Yun-gang WANG Zhong-gao JI Feng WU Ji-min CHEN Xiu LI Zhen DONG Shu-kui | 2009 | Chinese Medical Journal2009，，22： | 6 |
| 17 | Structure instability forecasting and analysis of giant rock pillars in steeply dipping thick coal seams显示文摘Structure stability analysis of rock masses is essential for forecasting catastrophic structure failure in coal seam mining. Steeply dipping thick coal seams(SDTCS) are common in the Urumqi coalfield, and some dynamical hazards such as roof collapse and mining-induced seismicity occur frequently in the coal mines. The cause of these events is mainly structure instability in giant rock pillars sandwiched between SDTCS. Developing methods to predict these events is important for safe mining in such a complex environment. This study focuses on understanding the structural mechanics model of a giant rock pillar and presents a viewpoint of the stability of a trend sphenoid fractured beam(TSFB). Some stability index parameters such as failure surface dips were measured, and most dips were observed to be between 46° and 51°. We used a digital panoramic borehole monitoring system to measure the TSFB's height(ΔH), which varied from 56.37 to 60.50 m. Next, FLAC3 D was used to model the distribution and evolution of vertical displacement in the giant rock pillars; the results confirmed the existence of a TSFB structure. Finally, we investigated the acoustic emission(AE) energy accumulation rate and observed that the rate commonly ranged from 20 to 40 k J/min. The AE energy accumulation rate could be used to anticipate impeding seismic events related to structure failure. The results presented provide a useful approach for forecasting catastrophic events related to structure instability and for developing hazard prevention technology for mining in SDTCS. | Xing-ping Lai Huan Sun Peng-fei Shan Ming Cai Jian-tao Cao Feng Cui | 2015 | International Journal of Minerals,Metallurgy and Materials2015，22，12： | 6 |
| 18 | Etiological features of cirrhosis inpatients in Beijing, China显示文摘 | SONG Guang-jun FENG Bo RAO Hui-ying WEI Lai | 2013 | Chinese Medical Journal2013，，13： | 5 |
| 19 | Salidroside Protects Against 6-Hydroxydopamine-Induced Cytotoxicity by Attenuating ER Stress显示文摘Parkinson's disease(PD) is a neurodegenerative disease characterized by a persistent decline of dopaminergic(DA) neurons in the substantia nigra pars compacta. Despite its frequency, effective therapeutic strategies that halt the neurodegenerative processes are lacking, reinforcing the need to better understand the molecular drivers of this disease. Importantly, increasing evidence suggests that the endoplasmic reticulum(ER)stress-induced unfolded protein response is likely involved in DA neuronal death. Salidroside, a major compound isolated from Rhodiola rosea L., possesses potent antioxidative stress properties and protects against DA neuronal death. However, the underlying mechanisms are not well understood. In the present study, we demonstrate that salidroside prevents 6-hydroxydopamine(6-OHDA)-induced cytotoxicity by attenuating ER stress. Furthermore, treatment of a DA neuronal cell line(SN4741) and primary cortical neurons with salidroside significantly reduced neurotoxin-induced increases in cytoplasmic reactive oxygen species and calcium, both of which cause ER stress, and cleaved caspase-12, which is responsible for ER stress-induced cell death. Together, these results suggest that salidroside protects SN4741 cells and primary cortical neurons from 6-OHDA-induced neurotoxicity by attenuating ER stress. This provides a rationale for the investigation of salidroside as a potential therapeutic agent in animal models of PD. | Kai Tao Bao Wang Dayun Feng Wei Zhang Fangfang Lu Juan Lai Lu Huang Tiejian Nie Qian Yang | 2016 | Neuroscience Bulletin2016，32，1： | 5 |
| 20 | Advances and Prospects of Surface Modification on Nickel-Rich Materials for Lithium-Ion Batteries显示文摘Although layered Ni-rich cathode materials have attracted lots of attention for their high capacity and power density,several significant issues,such aspoor thermal stability and moderate oyclability lit their practical appications.Most of these undesired problems of Ni-rich materials are caused by theunstable surface or the parasic reactions at cathode-electrolyte interface.5urface coating is the most common method to suppress such interfacialproblems for Ni-rich materials.This review focuses on the surface engineering of the N-rich materials in recent years,including the species used in coat.ing synthetic strategies of uniform coating layer,and the positive effects of coating species on the active materials.Detailed discussions are also taken todescribe the formation mechanism of the surface coating layer with design philosophy.Finally,the prospects for further developments and challenges insurface coating are also summarized. | Yuefeng Su Gang Chen Lai Chen Qing Li Yun Lu Liying Bao Ning Li Shi Chen Feng Wu | 2020 | Chinese Journal of Chemistry2020，38，12： | 5 |
您所在的机构暂未开通此部分的功能，请联系管理员