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| 1 | 血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI. | Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A | 2014 | 中华神经外科疾病研究杂志2014，13，3： | 6 |
| 2 | Behavior of composite soil reinforced with natural fibers 显示文摘 | Ghavami K Filho R D T Barbosa N P B | 1999 | Cement and Concrete Composites1999，21，： | 1 |
| 3 | Development, validation and application of a methodbased on DI-SPME and GC-MS for determination ofpesticides of different chemical groups in surface andgroundwater samples 显示文摘 | Filho A M Santos F N D De Pereira PAP | 2010 | Microchemical Journal2010，96，1： | 1 |
| 4 | Formation of alkanes,alkylcycloalkanes and alkylbenzenes during the catalytic hydrocracking of vegetable oils显示文摘 | Brodzki D Djega-Mariadassou G | 1993 | Fuel1993，72，4： | 1 |
| 5 | Existence and uniform decay rates for viscoelastic problem with nonlinear boundary amping显示文摘 | Cavalcanti V N D Filho J S P | 2001 | Diff Integ Equa2001，14，1： | 1 |
| 6 | Adsorption of heavy metal ions and epoxidation catalysis using a new polyhedral oligomeric silsesquioxane显示文摘 | Soares I V Vieira E G Filho N L D | 2013 | Chemical Engineering Journal2013，218，： | 1 |
| 7 | Comparative study of biodiesel production from soybean oil and coconut oil using a multiple-stage ultra shear reactor显示文摘 | Da Silva N D L Batistella C B Maciel Filho R | 2011 | Chemical Engineering2011，25，： | 1 |
| 8 | Bifurcation analysis of third-order phase-locked loops 显示文摘 | Monteiro L H A Favaretto Filho D N Piquera J R C | 2004 | IEEE Signal Processing Letters2004，11，5： | 1 |
| 9 | Existence and uniform decay rates for viscoelastic problems with nonlinear boundary damping显示文摘 | Cavalcanti V N D Filho J S P | 2001 | Diff Integ Equa2001，14，1： | 1 |
| 10 | Founder effect of E180splice mutation in growth hormone receptor (GHR) gene identified in Brazilian patients with GH insensitivity显示文摘 | Jorge AA Menezes Filho HC Lins TS Guedes DR Damiani D Setian N | 2005 | Arq Bras Endocrinol Metabol2005，49，3： | 1 |
| 11 | First ultrasound-mediated one-pot synthesis of N-substituted amides 显示文摘 | Srivastava R M Filho N R Silva D C | 2009 | Ultrasonics Sonoehemistry2009，16，6： | 1 |
| 12 | Study of an organi- cally modified clay:selective adsorption of heavy metal ions and voltammetric determination of mercury ( II ) 显示文摘 | DIAS FILHO N L DO CARMO D R | 2006 | Talanta2006，68，3： | 1 |
| 13 | 显示文摘 | GRUHN N E FILHO D A BILL T G | 2002 | J Am Chem Soc2002，124，： | 1 |
| 14 | Blend compatibility of waste materials-cellulose acetate (from sugarcane bagasse) with polystyrene (from plastic cups) : diffusion of water, FTIR, DSC, TGA, and SEM study 显示文摘 | Meireles C D S Filho G R Assuncao R M N | 2007 | J Appl Polym Sci2007，104，2： | 1 |
| 15 | Development, validation and applicationof a method based on DI -SPME and GC - MS for determination of pesticides of different chemical groups in surface and groundwater samples original research Article 显示文摘 | Filho AM Santos F N D Pereira PAD P | 2010 | Microchem J2010，96，1： | 1 |
| 16 | Synthesis of magnese ferrite nanoparticles in macroporous styrenedivinylbenzene copolymer显示文摘 | Rabelo D Lima E C D Tavares Filho N | 2004 | J of Magnetism and Magnetic Mater2004，，： | 1 |
| 17 | Behaviour of composite soil reinforced with natural fibres 显示文摘 | GHAVAVAMI K FILHO R D T BARBOSA N P | 1999 | Cementand Concrete Composites1999，21，1： | 1 |
| 18 | Optimization of mass concrete construction using genetic algorithms 显示文摘 | Fairbairn E M Silvoso M M Toledo Filho R D Alves J E L Ebecken N F | 2004 | Computers & structures2004，82，2： | 1 |
| 19 | An immersive and collaborative visualization system for digital manufac- turing 显示文摘 | Filho N D Botelho S C Carvalho J T | 2010 | The International Journal of Advanced Manu- facturing Technology2010，，： | 1 |
| 20 | Kinetics of enzyme-catalyzed alcoholysis of soybean oil in n-Hexane显示文摘 | Oliveira D D Filho I D N Luccio M D | 2005 | Appl Biochem Biotechnol2005，121，13： | 1 |
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