| 3 | 光学材料和外观设计对前囊混浊和撕囊收缩的影响显示文摘PURPOSE: To examine the influence of optic material (silicone and hydrophobic acrylic) and haptic design (one-piece and three-piece open loop) of sharp optic edge intraocular lenses (IOL) on anterior capsule opacification (ACO) and capsulorrhexis contraction. DESIGN: Randomized,controlled,double-blind clinical trial with intraindividual comparison. METHODS: This study was performed at the Department of Ophthalmology,Medical University of Vienna,Austria,and comprised 210 eyes of 105 patients with bilateral age-related cataract. In group 1 (n=53 patients),a three-piece acrylic IOL was compared with a three-piece silicone IOL. In group 2 (n=52 patients),the three-piece acrylic IOL was compared with the one-piece acrylic IOL. One year after the operation,standardized digital slit-lamp images of ACO were taken; 1 week and 1 year after the operation,digital retroillumination images were taken to assess capsulorrhexis size. The intensity of ACO was graded objectively (score,0% to 100% ),and the capsulorrhexis area (square millimeters) was determined objectively. RESULTS: One year after surgery,the mean ACO score was 21% for the acrylic and 20% for the silicone IOL (P =.4) in group 1 and 18% for both the three-piece and one-piece acrylic IOLs (P=.87) in group 2. Concerning the amount of capsulorrhexis contraction,there was no significant difference between the IOL types that were evaluated in this study (after Bonferroni-Holm correction,P > .05). CONCLUSION: In the hydrophobic sharp optic edge IOLs that were examined,neither the optic material nor the haptic design had an influence on the amount of ACO or capsulorrhexis contraction. | Sacu S. Menapace R. Findl O. 杨秀梅(译) | 2006 | 世界核心医学期刊文摘(眼科学分册)2006，2，6： | 0 |
| 4 | Elschnig珍珠个体形态的每日变化显示文摘PURPOSE: To observe and document the daily changes in the morphology of Elschnig pearls. DESIGN: A prospective cohort study. METHODS: Twenty-nine pseudophakic eyes with pronounced,regeneratory posterior capsule opacification (PCO) were included in this prospective study. Retroillumination images were taken at days 0,1,2,and 14. A square grid was laid over the images. Increase,decrease,appearance,and disappearance of pearls between the follow-up images were quantified. RESULTS: A total of 1371 areas (mean: 53/eye)-of 26 eyes were analyzed between days 0 and 1 and 1 and 2,and 896 areas (50/eye) of 18 eyes between days 0 and 14. Between days 0 and 1,days 1 and 2,and days 0 and 14,we observed 'no change' in pearl size in 72% ,77% ,and 32% ,a 'minor increase' in 16% ,14% ,and 10% ,a 'major increase' in 4% ,3% ,and 42% ,a 'minor decrease' in 14% ,11% ,and 11% ,and a 'major decrease' in 4% ,3% ,and 37% ,respectively. Appearance of newly formed pearls was found in 1% ,1% ,and 9% and disappearance of pearls in 1% ,1% ,and 5% ,respectively. CONCLUSIONS: Significant changes in the morphology of Elschnig pearls were observed within time intervals of only 24 hours. Appearance and disappearance of pearls,as well as progression and regression of pearls within these short intervals illustrate the dynamic behavior of regeneratory PCO. These findings may contribute to a better understanding of PCO and have implications on pharmaceutical interventions for PCO. | Neumayer T. Findl O. Buehl W. Georgopoulos M. 王海燕(译) | 2006 | 世界核心医学期刊文摘(眼科学分册)2006，2，6： | 0 |
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