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| 1 | Cardiac pathology in death from electrocution显示文摘 | Fineschi V Karch SB D'Errico S | 2005 | Int J Leg Med2005,10,: | 1 |
| 2 | Conduction disorder and primary cardiac tumor: a fatal case of multiple lipomas of the right atrium显示文摘Cardiac primary tumors are uncommon with an estimated prevalence between 0.17%and 0.19%.[1,2]Cardiac lipoma are extremely rare representing only 10%?19%of primary cardiac tumors and only few are symptomatic,depending on their location within the heart.[3,4]They originate from the subendocardium(50%),subepicardium(25%)or myocardium(25%)and with different sizes and locations.[5]Few cases of sudden death due to primary cardiac tumors are reported in literature(0.0025%);in these cases,conductive and haemodinamic abnormalities have been indicated as the cause of death. | Stefano D’Errico Andrea Mazzanti Paola Frati Vittorio Fineschi | 2019 | Journal of Geriatric Cardiology2019,16,5: | 1 |
| 3 | Correlation between left atrial size,prothrombotic state and markers of endothelial dysfunction in patients with long chronic nonrheumatic atrial fibrillation显示文摘 | Sabatini L Agricola E Ammaturo T Guerrini F Barbati R Pastore M Fineschi D Nami R | 2000 | Int J Cardiol2000,,: | 1 |
| 4 | Insight into stress induced cardiomyopathy and suddencardiac death due to stress, a forensic cardio pathologist point of view显示文摘 | FINESCHI V MICHALODIMITRAKIS M D'ERRICO S | 2010 | For Sci Int2010,194,1: | 1 |
| 5 | The impact of gender on fractional flow reserve measurements显示文摘 | Fineschi M Guerrieri G Orphal D etal | 2013 | EuroIntervention2013,9,3: | 1 |
| 6 | Cardiac pathology in death from electrocution显示文摘 | Fineschi V Karch SB D′Errico S | 2006 | Interna J Leg Med2006,120,2: | 1 |
| 7 | Comparative organization of chloroplast,mitochondrial and nuclear diversity in plant populations显示文摘 | Petit RJ Duminil J Fineschi S Hampe A Salvini D Vendramin GG | | 0,,: | 1 |
| 8 | Cardiac pathology in death from electrocution显示文摘 | Fineschi V Karch SB D' Errico S | 2006 | Int J Leg Med2006,120,2: | 1 |
| 9 | Comparative organization of chloroplast, mitochondrial and nuclear diversity in plant populations 显示文摘 | Petit R J Duminil J Fineschi S Hampe A Salvini D Vendramin GG | 2005 | Mol Ecol2005,14,3: | 1 |
| 10 | Atypical antipsychotics and oxidative cardiotoxicity:review of literature and future perspectives to prevent sudden cardiac death显示文摘Oxidative stress is considered the principal mediator of myocardial injury under pathological conditions.It is well known that reactive oxygen(ROS)or nitrogen species(RNS)are involved in myocardial injury and repair at the same time and that cellular damage is generally due to an unbalance between generation and elimination of the free radicals due to an inad-equate mechanism of antioxidant defense or to an increase in ROS and RNS.Major adverse cardiovascular events are often asso-ciated with drugs with associated findings such as fibrosis or inflammation of the myocardium.Despite efforts in the preclinical phase of the development of drugs,cardiotoxicity still remains a great concern.Cardiac toxicity due to second-generation anti-psychotics(clozapine,olanzapine,quetiapine)has been observed in preclinical studies and described in patients affected with mental disorders.A role of oxidative stress has been hypothesized but more evidence is needed to confirm a causal relationship.A better knowledge of cardiotoxicity mechanisms should address in the future to establish the right dose and length of treatment without impacting the physical health of the patients. | Stefano D’Errico Raffaele La Russa Aniello Maiese Alessandro Santurro Matteo Scopetti Silvia Romano Martina Zanon Paola Frati Vittorio Fineschi | 2021 | Journal of Geriatric Cardiology2021,18,8: | 0 |
| 11 | Mesenchymal stem cells in neurodegenerative diseases: Opinion review on ethical dilemmas显示文摘The treatment of neurodegenerative diseases presents a growing need for innovation in relation to recent evidence in the field of reconstructive therapy using stem cells. Understanding the molecular mechanisms underlying neurodegenerative disorders, and the advent of methods able to induce neuronal stem cell differentiation allowed to develop innovative therapeutic approaches offering the prospect of healthy and perfectly functional cell transplants, able to replace the sick ones. Hence the importance of deepening the state of the art regarding the clinical applications of advanced cell therapy products for the regeneration of nerve tissue. Besides representing a promising area of tissue transplant surgery and a great achievement in the field of neurodegenerative disease, stem cell research presents certain critical issues that need to be carefully examined from the ethical perspective. In fact, a subject so complex and not entirely explored requires a detailed scientific and ethical evaluation aimed at avoiding improper and ineffective use, rather than incorrect indications, technical inadequacies, and incongruous expectations. In fact, the clinical usefulness of stem cells will only be certain if able to provide the patient with safe, long-term and substantially more effective strategies than any other treatment available.The present paper provides an ethical assessment of tissue regeneration through mesenchymal stem cells in neurodegenerative diseases with the aim to rule out the fundamental issues related to research and clinical translation. | Matteo Scopetti Alessandro Santurro Vittorio Gatto Raffaele La Russa Federico Manetti Stefano D’Errico Paola Frati Vittorio Fineschi | 2020 | World Journal of Stem Cells2020,12,3: | 0 |
| 12 | Pancreatic transplant surgery and stem cell therapy:Finding the balance between therapeutic advances and ethical principles显示文摘The latest achievements in the field of pancreas transplantation and stem cell therapy require an effort by the scientific community to clarify the ethical implications of pioneering treatments,often characterized by high complexity from a surgical point of view,due to transplantation of multiple organs at the same time or at different times,and from an immunological point of view for stem cell therapy.The fundamental value in the field of organ transplants is,of course,a solidarity principle,namely that of protecting the health and life of people for whom transplantation is a condition of functional recovery,or even of survival.The nature of this value is that of a concept to which the legal discipline of transplants entrusts its own ethical dignity and for which it has ensured a constitutional recognition in different systems.The general principle of respect for human life,both of the donor and of the recipient,evokes the need not to put oneself and one’s neighbor in dangerous conditions.The present ethical reflection aims to find a balance between the latest therapeutic advances and several concepts including the idea of the person,the respect due to the dead,the voluntary nature of the donation and the consent to the same,the gratuitousness of the donation,the scientific progress and the development of surgical techniques,and the policies of health promotion. | Martina Padovano Matteo Scopetti Federico Manetti Donato Morena Davide Radaelli Stefano D’Errico Nicola Di Fazio Paola Frati Vittorio Fineschi | 2022 | World Journal of Stem Cells2022,14,8: | 0 |