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| 1 | Hydrogen breath test for the diagnosis of lactose intolerance,is the routine sugar load the best one?显示文摘AIM: To evaluate the prevalence of lactose intolerance (LI) following a load of 12.5 g in patients diagnosed as high-grade malabsorbers using the hydrogen breath test (HBT)-25.METHODS: Ninety patients showing high-grade malabsorption at HBT-25 were submitted to a second HBT with a lactose load of 12.5 g.Peak hydrogen production,area under the curve of hydrogen excretion and occurrence of symptoms were recorded.RESULTS: Only 16 patients (17.77%) with positive HBT-25 proved positive at HBT-12.5.Hydrogen production was lower as compared to HBT-25 (peak value 21.55 parts per million (ppm) ± 29.54 SD vs 99.43 ppm ± 40.01 SD; P < 0.001).Symptoms were present in only 13 patients.The absence of symptoms during the high-dose test has a high negative predictive value (0.84) for a negative low-dose test.The presence of symptoms during the first test was not useful for predicting a positive low-dose test (positive predictive value 0.06-0.31).CONCLUSION: Most patients with a positive HBT-25 normally absorb a lower dose of lactose and a strict lactose restriction on the basis of a 'standard' HBT is,in most instances,unnecessary.Thus,the 25 g lactose tolerance test should probably be substituted by the 12.5 g test in the diagnosis of LI,and in providing dietary guidelines to patients with suspected lactose malabsorption/intolerance. | Fiorenza Argnani Mauro Di Camillo Vanessa Marinaro Tiziana Foglietta Veronica Avallone Carlo Cannella Piero Vernia | 2008 | World Journal of Gastroenterology2008，14，40： | 3 |
| 2 | Neutrophil gelatinase-associated lipocalin does not predict acute kidney injury in heart failure显示文摘BACKGROUND Acute cardiorenal syndrome type 1(CRS-1)is defined by a rapid cardiac dysfunction leading to acute kidney injury(AKI).Neutrophil gelatinaseassociated lipocalin(NGAL)is expressed on the surface of human neutrophils and epithelial cells,such as renal tubule cells,and its serum(sNGAL)and urinary have been used to predict AKI in different clinical settings.AIM To characterize CRS-1 in a cohort of patients with acute heart diseases,evaluating the potentiality of sNGAL as an early marker of CRS-1.METHODS We performed a retrospective cohort,multi-centre study.From January 2010 to December 2011,we recruited 202 adult patients admitted to the coronary intensive care unit(CICU)with a diagnosis of acute heart failure or acute coronary syndrome.We monitored the renal function to evaluate CRS-1 development and measured sNGAL levels within 24 h and after 72 h of CICU admission.RESULTS Overall,enrolled patients were hemodynamically stable with a mean arterial pressure of 92(82-107)mmHg,55/202(27.2%)of the patients developed CRS-1,but none of them required dialysis.Neither the NGAL delta value(AUC 0.40,95%CI:0.25-0.55)nor the NGAL peak(AUC 0.45,95%CI:0.36-0.54)or NGAL cutoff(≥140 ng/mL)values were statistically significant between the two groups(CRS-1 vs no-CRS1 patients).The area under the ROC curve for the prediction of CRS-1 was 0.40(95%CI:0.25-0.55)for the delta NGAL value and 0.45(95%CI:0.36-0.54)for the NGAL peak value.Finally,in multivariate analysis,the risk of developing CRS-1 was correlated with age>60 years,urea nitrogen at admission and 24 h-urine output(AUC 0.83,SE=60.5%SP=93%),while sNGAL was not significantly correlated.CONCLUSION In our population,sNGAL does not predict CRS-1,probably as a consequence of the mild renal injury and the low severity of heart disease.So,these data might suggest that patient selection should be taken into account when considering the utility of NGAL measurement as a biomarker of kidney damage. | Fiorenza Ferrari Elisa Scalzotto Pasquale Esposito Sara Samoni Flavio Mistrorigo Lilia Maria Rizo Topete Massimo De Cal Grazia Maria Virzì Valentina Corradi Rossella Torregrossa Roberto Valle Stefania Bianzina Nadia Aspromonte Matteo Floris Alessandro Fontanelli Alessandra Brendolan Claudio Ronco | 2020 | World Journal of Clinical Cases2020，8，9： | 3 |
| 3 | Predatory impact of the mosquito fish (Gambusia holbrooki Girard) on zooplanktonic populations in a pond at Tenuta di Castelporziano (Rome, Central Italy)显示文摘 | Fiorenza G M Omella F Daria V | 2001 | Limnol2001，60，2： | 1 |
| 4 | A suitable marker for assessing the freshness of royal jelly 显示文摘 | Emanuele Marconi Maria Fiorenza Caboni Maria Cristina Messia | 2002 | J Agri and Food Chemistry2002，50，： | 1 |
| 5 | Experimental comparison of RF power LDMOSFETs on thin-film SOI and bulk silicon显示文摘 | Fiorenza J G del Alamo J A | 2002 | IEEE Trans Elec Dev2002，49，4： | 1 |
| 6 | The results of endoprosthetic replacement for tumours of the distal humerus显示文摘 | KULKARNI A FIORENZA F GRIMER R J | 2003 | J Bone Joint Surg Br2003，85，2： | 1 |
| 7 | Monitoring fracture propagation in a soft rock(Neapolitan Tuff) using acoustic emissions and dig- ital images显示文摘 | STEPHEN A HALL FIORENZA de SANCTIS GIOAC- CHINO VIGGIANI | 2006 | Pure appl Geo Phys2006，163，10： | 1 |
| 8 | Indices of Orlicz spaces and some applications显示文摘 | FIORENZA A KRBEC M | 1997 | Comment Math Univ Carolinae1997，38，3： | 1 |
| 9 | The maximal function on variable Lp spaces显示文摘 | Cruz-Uribe D Fiorenza A Neugebauer C J | 2003 | Annales Academiae Scientiarum Fennicae Mathematica2003，28，1： | 1 |
| 10 | Effects of Simvastatin on Blood Pressure in Hypercholesterolemic Patients:An Open-Label Study in Patients with Hypertension显示文摘 | Adriana Branchi Anna Maria Fiorenza | 2004 | Current therapeutic research2004，65，3： | 1 |
| 11 | Supercritical carbon dioxide extraction of phospholipids from dried egg yolk without organic modifier显示文摘 | Emanuele Boselli Maria Fiorenza Caboni | 2000 | Journal of supercritical Fluids2000，19，： | 1 |
| 12 | Giant calcified thoracic herniated disc:considerations aiming a proper surgical strategy显示文摘 | Barbanera A Serchi E Fiorenza V | 2009 | J Neurosurg Sci2009，53，1： | 1 |
| 13 | Effect of processing and storage on the chemical quality markers of spray-dried whole egg 显示文摘 | Maria Fiorenza Caboni Emanuele Boselli Maria Cristina Messia | 2005 | Food Chemistry2005，92，2： | 1 |
| 14 | Supercritical carbon dioxide extraction of phospholipids from dried egg yolk without organic modifier显示文摘 | Emanuele Boselli Maria Fiorenza Caboni | 2000 | Journal of Supercritical Fluids2000，，19： | 1 |
| 15 | Extensible endoprothesee of the humerus after resection of bone tumors显示文摘 | Ayoub KS Fiorenza F Grimer RJ | 1999 | J Bone Joint Surg(Br)1999，81，3： | 1 |
| 16 | Lowering effects of four different statins on serum triglyceride level显示文摘 | Branchi A Fiorenza AM Rovellini A | 1999 | Eur J Clin Pharmacol1999，55，7： | 1 |
| 17 | Evaluation of lipid oxidation in spaghetti pasta enriched with long chain n ?3 polyunsaturated fatty acids under different storage conditions显示文摘 | Vito Verardo Federico Ferioli Ylenia Riciputi Giovanna Iafelice Emanuele Marconi Maria Fiorenza Caboni | 2008 | Food Chemistry2008，，： | 1 |
| 18 | Quantitative studies of the hepatitis B viral Pre-S: proteins: lack of correlation with the HBeAg status显示文摘 | Hu PS Carithers RLJ Fiorenza V | 1987 | Virol Methods1987，16，： | 1 |
| 19 | Immunological consequences of three doses of heat-killed Mycobacterium vaccae in the immunotherapy of tuberculosis显示文摘 | Dlugovitzky D Fiorenza G Farroni M | 2006 | Respir Med2006，100，6： | 1 |
| 20 | Learning at the boundaries in an “Open Regional Innovation System”: A focus on firms’ innovation strategies in the Emilia Romagna life science industry显示文摘 | Fiorenza Belussi Alessia Sammarra Silvia Rita Sedita | 2010 | Research Policy2010，，6： | 1 |
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