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| 1 | Esophageal tissue engineering:A new approach for esophageal replacement显示文摘A number of congenital and acquired disorders require esophageal tissue replacement.Various surgical techniques,such as gastric and colonic interposition,are standards of treatment,but frequently complicated by stenosis and other problems.Regenerative medicine approaches facilitate the use of biological constructs to replace or regenerate normal tissue function.We review the literature of esophageal tissue engineering,discuss its implications,compare the methodologies that have been employed and suggest possible directions for the future.Medline,Embase,the Cochrane Library,National Research Register and ClinicalTrials.gov databases were searched with the following search terms:stem cell and esophagus,esophageal replacement,esophageal tissue engineering,esophageal substitution.Reference lists of papers identified were also examined and experts in this field contacted for further information.All full-text articles in English of all potentially relevant abstracts were reviewed.Tissue engineering has involved acellular scaffolds that were either transplanted with the aim of being repopulated by host cells or seeded prior to transplantation.When acellular scaffolds were used to replace patch and short tubular defects they allowed epithelial and partial muscular migration whereas when employed for long tubular defects the results were poor leading to an increased rate of stenosis and mortality.Stenting has been shown as an effective means to reduce stenotic changes and promote cell migration,whilst omental wrapping to induce vascularization of the construct has an uncertain benefit.Decellularized matrices have been recently suggested as the optimal choice for scaffolds,but smart polymers that will incorporate signalling to promote cell-scaffold interaction may provide a more reproducible and available solution.Results in animal models that have used seeded scaffolds strongly suggest that seeding of both muscle and epithelial cells on scaffolds prior to implantation is a prerequisite for complete esophageal replacement.Novel approaches need to be designed to allow for peristalsis and vascularization in the engineered esophagus.Although esophageal tissue engineering potentially offers a real alternative to conventional treatments for severe esophageal disease,important barriers remain that need to be addressed. | Giorgia Totonelli Panagiotis Maghsoudlou Jonathan M Fishman Giuseppe Orlando Tahera Ansari Paul Sibbons Martin A Birchall Agostino Pierro Simon Eaton Paolo De Coppi | 2012 | World Journal of Gastroenterology2012，18，47： | 5 |
| 2 | The value of transvaginal sonography in the preoperative assessment of myometrial invasion in high and low grade endometrial cancer and in comparison to frozen section in grade 1disease 显示文摘 | Altaras M Bernheim J | 2000 | Eur J Gynaecol Oncol2000，21，： | 1 |
| 3 | The value of transvaginal sonography in the preoperative assessment of myomeyrial invasion in high and lowgrade endometrial cancer and in comparison to frozen section in grade 1 disease显示文摘 | Fishman A Altaras M Bemheim j | 2000 | Eur j Gynaecol Oneo2000，21，1： | 1 |
| 4 | Combination antiviral therapy for ganciclovir-resistant cytomegalovirus infection in solidorgan transplant recipients显示文摘 | MYLONAKIS E KALLAS W M FISHMAN J A | 2002 | Clin Infect Dis2002，34，： | 1 |
| 5 | Successful carboplatin desensitization in patients with proven carboplatin al- lergy显示文摘 | CONFINO C FISHMAN A ALTARAS M | 2005 | Cancer2005，104，3： | 1 |
| 6 | Correlation of optical coherence tomography findings with visual acuity and macular lesions in patients with X-linked retinoschisis显示文摘 | APUSHKIN M A FISHMAN G A JANOWICZ M J | 2005 | Ophthalmology2005，112，3： | 1 |
| 7 | Indirect reciprocity among imperfect individuals显示文摘 | Fishman M A | 2003 | Journal of Theoretical Biology2003，225，3： | 1 |
| 8 | Acute plasticity in the human somatosensory cortex following amputation 显示文摘 | Borsook d Beeerra L Fishman S Edwards A Jennings CL Stojanovic M Papinicolas L Ramachandran VS Gonzalez RG Breiter H | 1998 | Neuroreport1998，9，6： | 1 |
| 9 | The effect of modified citrus pectin on urinary excretion of toxic elements显示文摘 | ELIAZ I HOTCHKISS A T FISHMAN M L | 2006 | Phytotherapy Research2006，20，10： | 1 |
| 10 | Kinetic resolution of a diltiazem intermediate by lipase-catalyzed enantioselective alcoholysis显示文摘 | Shapira-Levinger M Fishman A | 2000 | J Mol Catal B:enzymatic2000，9，46： | 1 |
| 11 | A two-step enzymatic resolution process for large-scale production of (S)- and (R)-ethyl-3-hydroxybutyrate 显示文摘 | Fishman A Eroshov M Dee-Noor S | 2001 | Biotech Bioeng2001，74，3： | 1 |
| 12 | Radiometric detectionof spread-spectrum signals in noise of uncertain power显示文摘 | Sonnenschein A Fishman P M | 1992 | IEEE Trans on AES1992，28，3： | 1 |
| 13 | Ureteroscopic and extirpative treatment of upper urinary tract urothe- lial carcinoma: a 15-year comprehensive review of 160 consecutive patients 显示文摘 | Grasso M Fishman A I Cohen J | 2012 | BJU Int2012，110，11： | 1 |
| 14 | Improving process conditions of hydroxytyrosol synthesis by toluene-4-monooxygenase显示文摘 | Brouk M Fishman A | 2012 | J Mol Catal B: Enzym2012，84，： | 1 |
| 15 | Protein engineering of toluene monooxygenases for synthesis of hydroxytyrosol显示文摘 | Brouk M Fishman A | 2009 | Food Chemistry2009，116，1： | 1 |
| 16 | Asymmetric evolutionary games with non-linear pure strategy payoffs 显示文摘 | Fishman M A | 2008 | Games and Economic Behavior2008，63，： | 1 |
| 17 | A two-step enzymatic resolution process for large-scale production of (S) - and (R) -ethyl-3-hydroxybutyrate 显示文摘 | Fishman A Eroshov M Dee-Noor S S | 2014 | Bioorganic & MediCinal Chemistry2014，20，22： | 1 |
| 18 | Bioproduction of 2- phenylethanol in a biphasic ionic liquid aqueous system 显示文摘 | Sendovski M Nir N Fishman A | 2010 | Journal of Agricultural and Food Chemistry2010，58，4： | 1 |
| 19 | Radiometric detection of spread-spectrum signals in noise of uncertain power显示文摘 | SONNENSCHEIN A FISHMAN P M | 1992 | IEEE Trans Aerosp Electron Syst1992，28，3： | 1 |
| 20 | Evolution of Cooperation between Individuals 显示文摘 | Lotem A Fishman M A Stone L | 1999 | Nature1999，，400： | 1 |
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