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| 1 | Chronic hepatitis C virus infection and atherosclerosis: Clinical impact and mechanisms显示文摘Hepatitis C virus(HCV)infection represents a major health issue worldwide due to its burden of chronic liver disease and extrahepatic manifestations including cardiovascular diseases,which are associated with excess mortality.Analysis of published studies supports the view that HCV infection should be considered a risk factor for the development of carotid atherosclerosis,heart failure and stroke.In contrast,findings from studies addressing coronary artery disease and HCV have yielded conflicting results.Therefore,meta-analytic reviews and prospective studies are warranted.The pathogenic mechanisms connecting HCV infection,chronic liver disease,and atherogenesis are not completely understood.However,it has been hypothesized that HCV may promote atherogenesis and its complications through several direct and indirect biological mechanisms involving HCV colonization and replication within arterial walls,liver steatosis and fibrosis,enhanced and imbalanced secretion of inflammatory cytokines,oxidative stress,endotoxemia,mixed cryoglobulinemia,perturbed cellular and humoral immunity,hyperhomocysteinemia,hypo-adiponectinaemia,insulin resistance,type 2 diabetes and other components of the metabolic syndrome.Understanding these complex mechanisms is of fundamental importance for the development of novel therapeutic approaches to prevent and to treat vascular complications in patients with chronic HCV infection.Currently,it seems that HCV clearance by interferon and ribavirin treatment significantly reduces non-liver-related mortality;moreover,interferon-based treatment appears to decrease the risk of ischemic stroke. | Luigi E Adinolfi Rosa Zampino Luciano Restivo Amedeo Lonardo Barbara Guerrera Aldo Marrone Fabio Nascimbeni Anna Florio Paola Loria | 2014 | World Journal of Gastroenterology2014，20，13： | 6 |
| 2 | Biochemical markers of perinatal brain damage显示文摘 | Florio P Abella R Marinoni E | 2010 | Front Biosci (Schol Ed)2010，2，： | 1 |
| 3 | Mycobacterium tuberculosis FurA autoregulates its own expression 显示文摘 | Sala C Forti F Di Florio E | 2003 | J Bacteriol2003，185，18： | 1 |
| 4 | In vitro susceptibility of Candida species to fiveantifungal agents in a German universityhospital assessed by the reference brothmicrodilution method and Etest显示文摘 | DE Carolis E Sanguinetti M Florio A R | 2010 | JChemother2010，22，1： | 1 |
| 5 | Strategies for the prevention of asthmatic, anaphylactic and anaphylactoid reactions during the administration of anesthetics and/or contrast media 显示文摘 | Liccardi G Lobefalo G Di Florio E | 2008 | J Investig Allergol Clin Immunol2008，18，1： | 1 |
| 6 | Integrating AVHRR Satellite Data and NOAA Ground Observations to Predict Surface Air Temperature: A Statistical Approach显示文摘 | Florio E N Lele S R Chang Y C | 2004 | International Journal of Remote Sensing2004，25，15： | 1 |
| 7 | A protein phosphatase 2A inhibition assay for a fast and sensitive assessment of okadaic acid contamination in mussels 显示文摘 | Tubaro A Florio C Luxich E | 1996 | Toxicon1996，34，： | 1 |
| 8 | Suitability of the MTT-based cytotoxicity assay to detect okadaic acid contamination of mussels 显示文摘 | TUBARO A FLORIO C LUXICH E | 1996 | Toxicon1996，34，9： | 1 |
| 9 | Age-dependency and dietary influence on the hypothalamic ouabain-like factor in Milan hypertensive rats 显示文摘 | Ferrandi M Minotti E Florio M | 1995 | J Hypertens1995，13，122： | 1 |
| 10 | DNA methylation state of the galectin3 gene represents a potential new marker of thyroid malignancy显示文摘 | Keller S Angrisano T Florio E | 2013 | Oncol Lett2013，6，1： | 1 |
| 11 | Aprotein phosphatase 2A inhibition assay for a fast and sensitive assessment of okadaic acid contamination in mussels 显示文摘 | Tubaro A Florio C Luxich E | 1996 | Toxicon1996，34，： | 1 |
| 12 | Damage of porcine aortic valve tissue caused by the surfactant sodiumdodecylsulphate显示文摘 | Bodnar E Olsen EG Florio R | 1986 | Thorac cardiovasc surg1986，34，2： | 1 |
| 13 | Suitability of the MTTbased cytotoxicity assay to detect okadaic acid contamination of mussels显示文摘 | Tubaro A Florio C Luxich E | 1996 | Toxicon1996，34，： | 1 |
| 14 | A protein phosphatase 2A inhibition assay for a fast and sensitive assessment of okadaic acid contamination in mussels显示文摘 | TUBARO A FLORIO C LUXICH E | 1996 | Toxicon1996，34，7： | 1 |
| 15 | A retrospective ca- seeontrol study comparing hysteroscopic resection ver-sus hormonal modulation in treating menstrual disor-ders due to isthmocele 显示文摘 | Florio P Gubbini G Marra E | 2011 | Gynecol Endocrinol2011，27，6： | 1 |
| 16 | Biochemical markers of perinatal brain damage显示文摘 | Florio P Abella R Marinoni E | 2010 | Front Biosci2010，2，： | 1 |
| 17 | Urinary S100B protein concentrations are increased in intrauterine growth retarded newborns 显示文摘 | Florio P Marinoni E Dilorio R | 2006 | Pediatrics2006，118，3： | 1 |
| 18 | A retrospective case-con- trol study comparing hysteroscopic resection versus hormonal modulation in treating menstrual disorders due to isthmocele 显示文摘 | Florio P Gubbini G Marra E | 2011 | Gynecol Endocrinol2011，27，6： | 1 |
| 19 | Urinary S100B protein concentrations are increased in intrauterine growth-retarded newborns 显示文摘 | Florio P Marinoni E Iorio RD | 2006 | Pediatric2006，118，： | 1 |
| 20 | Genome-wide expression profiling of the response to short-term exposure to fluconazole in Crytococcus neoformans serotype A 显示文摘 | Florio AR Ferrari S De Carolis E | 2011 | BMC Microbiol2011，11，： | 1 |
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