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| 1 | 文献快报(8):美国儿科学会颁布新版儿童青少年高血压筛查与管理临床实践指南显示文摘美国儿科学会于2017年8月重新颁布了《儿童青少年高血压筛查与管理临床实践指南》(以下简称《新指南》),主要涉及了新的规范血压图表、筛查方案修订和启动药物降压治疗的推荐,此外指南还对儿童血压偏高和高血压筛查时间及动态血压监测进行了推荐。为促进儿科临床诊疗中血压偏高的早期发现,《新指南》纳入了简化表格用于筛查。以舒张压和收缩压的第90百分位值作为筛查阳性标准,需要进一步开展听诊器袖套方法确诊。 | FLYNN J T KAELBER D C BAKER-SMITH C M 孙莹 | 2017 | 中国学校卫生2017，38，10： | 57 |
| 2 | Management of infected pancreatic necrosis in the setting of concomitant rectal cancer:A case report and review of literature显示文摘BACKGROUND Pancreatitis with infected necrosis is a severe complication of acute pancreatitis and carries with it high rates of morbidity and mortality. The management of infected pancreatic necrosis alongside concomitant colorectal cancer has never been described in literature.CASE SUMMARY A 77 years old gentleman presented to the Emergency Department of our hospital complaining of ongoing abdominal pain for 8 h. The patient had clinical features of pancreatitis with a raised lipase of 3810 U/L, A computed tomography(CT) abdomen confirmed pancreatitis with extensive peri-pancreatic edema. During the course of his admission, the patient had persistent high fevers and delirium thought secondary to infected necrosis, prompting the commencement of broad-spectrum antibiotic therapy with Piperacillin/Tazobactam. Subsequent CT abdomen confirmed extensive pancreatic necrosis(over 70%). Patient was managed with supportive therapy,nutritional support and gut rest initially and improved over the course of his admission and was discharged 42 d post admission. He represented 24 d following his discharge with fever and chills and a repeat CT abdomen scan noted gas bubbles within the necrotic pancreatic tissue thereby confirming infected necrotic pancreatitis. This CT scan also revealed asymmetric thickening of the rectal wall suspicious for malignancy. A rectal cancer was confirmed on flexible sigmoidoscopy. The patient underwent two endoscopic necrosectomies and was treated with intravenous antibiotics and was discharged after 28 d.Within 1 wk post discharge, the patient commenced a course of neoadjuvant radiotherapy and subsequently underwent concomitant chemotherapy prior to undergoing a successful Hartmann's procedure for treatment of his colorectal cancer.CONCLUSION This case highlights the efficacy of endoscopic necrosectomy, early enteral feeding and targeted antibiotic therapy for timely management of infected necrotic pancreatitis. The prompt resolution of pancreatitis permitted the patient to undergo neoadjuvant treatment and resection for his concomitant colorectal cancer. | Kihoon Choi David E Flynn Anitha Karunairajah Andrew Hughes Ambika Bhasin Benedict Devereaux Manju D Chandrasegaram | 2019 | World Journal of Gastrointestinal Surgery2019，11，4： | 2 |
| 3 | Long-term control of Myeobacterium tuberculosis infection is mediated by dynamic immune response显示文摘 | Lazarevic V Nolt D Flynn JL | 2005 | Immunol2005，175，5： | 1 |
| 4 | Characterization of the genetic locus responsible for the production of ABP-118,a novel bacteriocin produced by the probiotics bacterium lactobacillus salivarius subspsalivarius UCC118显示文摘 | Flynn S Van Sinderen D Thorn GM | 2002 | Microbiology2002，148，4： | 1 |
| 5 | Thalidomide is an inhibitor of angiogenesis显示文摘 | D'Amato RJ Loughnan MS Flynn E Folkman J | 1994 | Proc Natl Acad Sci U S A1994，91，： | 1 |
| 6 | Optimal charging of electric w:hieles in low-voltage distribution systems 显示文摘 | RICHARDSON P FLYNN D KEANE A | 2011 | IEEE Transactions on Power Systems2011，，： | 1 |
| 7 | Coordinated utilization of wind farm reactive power capability for system loss optimization显示文摘 | Meeqahapola L Durairaj S Flynn D | | European Transactions on Electrical Power0，21，1： | 1 |
| 8 | Arginine degradation in developing porcine enterocytes显示文摘 | Wu G Knabe D A Flynn N E | 1996 | American Journal of Physiology-Gastrointestinal and Liver Physiology1996，271，5： | 1 |
| 9 | Relationship between landscape characteristics and Non-point sources pollution inputs to coastal Estuaries显示文摘 | BASNYAT P TEETER L D FLYNN K M | 1999 | Environmental Management1999，23，4： | 1 |
| 10 | Optimal charging ofelectric vehicles in low-voltage distribution systems 显示文摘 | Richardson P Flynn D Keane A | 2012 | IEEE Trans on Power Systems2012，27，1： | 1 |
| 11 | Taxonomic, phylogenetie, and environmental trade-offs between leaf productivity and persistence 显示文摘 | HE J S WANG X P FLYNN D F B | 2009 | Ecology2009，90，10： | 1 |
| 12 | Thalidomide is an inhibitor of angiogenesis显示文摘 | D'Amato RJ Loughnan MS Flynn E | | 0，，： | 1 |
| 13 | Reliability and responsiveness of an 18 site,10-g monofilament examination for assessment of pro-tective foot sensation显示文摘 | Young D Schuerman S Flynn K | | 0，，2： | 1 |
| 14 | Re- ducing door to balloon time in patients with ST-eleva- tion myocardial infarction undergoing percutaneous coronary intervention: does a decrease in door to bal- loon time translate into a reduction in mortality? 显示文摘 | FLYNN A MOSCUCCI M SHARE D | 2009 | Circulation2009，120，： | 1 |
| 15 | Long-term control of Mycobacterium tuberculosis infection is mediated by dynamic immune responses显示文摘 | Lazarevic V Nolt D Flynn JL | 2005 | J Immunol2005，175，2： | 1 |
| 16 | Thalidomide is an inhibitor of angiogenesis显示文摘 | D'Amato RJ Loughnan MS Flynn E | 1994 | Proc Natl Acad Sci USA1994，91，10： | 1 |
| 17 | Diagnosis of psychiatric disorder in elderly general and geriatric hospital patients:AGECAT and DSM-Ⅲ -R compared显示文摘 | Ames D Flynn E Tuckwell V | 1994 | Int J Geriatr Psychiatry1994，9，： | 1 |
| 18 | Cyclooxy genase-2 inhibitors decrease interleukin-1 beta-stimulated prostagland in E2 and IL-6 production by human gingival fibroblasts显示文摘 | Tipton D A Flynn J C Stein S H | 2003 | J Periodontol2003，74，12： | 1 |
| 19 | Fabrication process of a micro-inductor utilising a magnetic thin film core 显示文摘 | FLYNN D SUDAN N S TOON A | 2006 | Microsystem Technologies2006，12，： | 1 |
| 20 | Thalidomide is an inhibitor of angiogenesis显示文摘 | D'AMATO R J LOUGHNAN M S FLYNN E | | 0，，： | 1 |
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