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| 1 | Randomized study of lafutidine vs lansoprazole in patients with mild gastroesophageal reflux disease显示文摘AIM: To compare the clinical efficacy of the secondgeneration H2 RA lafutidine with that of lansoprazole in Japanese patients with mild gastroesophageal reflux disease(GERD). METHODS: Patients with symptoms of GERD and a diagnosis of grade A reflux esophagitis(according to the Los Angeles classification) were randomized to receive lafutidine(10 mg, twice daily) or lansoprazole(30 mg, once daily) for an initial 8 wk, followed by maintenance treatment comprising half-doses of the assigned drug for 24 wk. The primary endpoint was the frequency and severity of heartburn during initial and maintenance treatment. The secondary endpoints were the sum score of questions 2 and 3 in the Gastrointestinal Symptom Rating Scale(GSRS), and the satisfaction score.RESULTS: Between April 2012 and March 2013, a total of 53 patients were enrolled, of whom 24 and 29 received lafutidine and lansoprazole, respectively. After 8 wk, the frequency and severity of heartburn was significantly reduced in both groups. However, lafutidine was significantly inferior to lansoprazole with regard to the severity of heartburn during initial and maintenance treatment(P = 0.016). The sum score of questions 2 and 3 in the GSRS, and satisfaction scores were also significantly worse in the lafutidine group than the lansoprazole group(P = 0.0068 and P = 0.0048, respectively).CONCLUSION: The clinical efficacy of lafutidine was inferior to that of lansoprazole, even in Japanese patients with mild GERD. | Ryuta Takenaka Hiroyuki Okada Seiji Kawano Yoshinori Komazawa Fumiya Yoshinaga Shinji Nagata Masafumi Inoue Hirohisa Komatsu Seiji Onogawa Yoshinori Kushiyama Shinichi Mukai Hiroko Todo Hideharu Okanobu Noriaki Manabe Shinji Tanaka Ken Haruma Yoshikazu Kinoshita | 2016 | World Journal of Gastroenterology2016，22，23： | 2 |
| 2 | Platinum nanoparticles coated by graphene layers: A low-metal loading catalyst for methanol oxidation in alkaline media显示文摘Platinum catalysts play a major role in the large scale commercialization of direct methanol fuel cells(DMFC).Here,we present a procedure to create a nanostructural graphene-platinum(Gr Pt)composite containing a small amount(5.3 wt%)of platinum nanoparticles coated with at least four layers of graphene.The composite,as Gr Pt ink,was deposited on a glassy carbon electrode and its electrocatalytic activity in a methanol oxidation reaction(MOR)was evaluated in a 1 M CH3OH/1 M NaOH solution.The results indicated an enhanced catalytic performance of GrPt towards MOR in alkaline media compared with the Pt/C material.Electron energy-loss spectroscopy and X-ray photoelectron spectroscopy(recorded before and after the electrochemical assays)were employed to analyze the changes in the chemical composition of the nanomaterial and to explain the transformations that took place at the electrode surface.Our findings suggest that growing of graphene on platinum nanoparticles improve the catalytic performance of platinum-graphene composites towards MOR in alkaline media. | Camelia Berghian-Grosan Teodora Radu Alexandru R.Biris Monica Dan Cezara Voice Fumiya Watanabe Alexandru S.Biris Adriana Vulcu | 2020 | Journal of Energy Chemistry2020，29，1： | 2 |
| 3 | Safe and effective sedation in endoscopic submucosal dissection for early gastric cancer: a randomized comparison between propofol continuous infusion and intermittent midazolam injection显示文摘 | Shinsuke Kiriyama Takuji Gotoda Hiromi Sano Ichiro Oda Fumiya Nishimoto Tetsuro Hirashima Chika Kusano Hiroyuki Kuwano | 2010 | Journal of Gastroenterology2010，，8： | 2 |
| 4 | CFD computations of NAL experimental airplane with rocket booster using overset unstructured grids显示文摘 | FUMIYA TOGASHI TAKESHI FUJITA YASUSHI ITO | 2005 | International Journal of Methanics Fluids2005，48，8： | 1 |
| 5 | Evaluation of intra-aneurysmal blood flow by digital subtraction angiography: blood flow change after coil embolization显示文摘 | Fumio Asakura Hiroshi Tenjin Noriaki Sugawa Satoshi Kimura Fumiya Oki | 2003 | Surgical Neurology2003，，4： | 1 |
| 6 | C02-perm- selective membranes of crosslinked poly( vinyl ether)s bear- ing oxyetbylene chains 显示文摘 | TOSHIKAZU S FUMIYA K ATSUYA I | 2014 | Polymer2014，55，6： | 1 |
| 7 | Amelioration of ischemia/reperfusion-induced myocardial infarction by the 2-alkynyladenosine derivative 2-octynyladenosine (YT-146)显示文摘 | Jun Sasamori Kazuyuki Aihara Fumiya Yoneyama | 2006 | J Cardiovasc Pharmacol2006，47，： | 1 |
| 8 | Current understanding of allergic transfusion reactions: incidence, pathogenesis, laboratory tests, prevention and treatment显示文摘 | Fumiya Hirayama | 2013 | Br J Haematol2013，160，4： | 1 |
| 9 | Self-organization,embodiment and biologically inspired robotics显示文摘 | Rolf P Max L Fumiya L | 2007 | Science2007，318，5853： | 1 |
| 10 | Current understanding of aller- gic transfusion reactions:incidence, pathogenesis, labora- tory tests, prevention and treatment显示文摘 | FUMIYA HIRAYAMA | 2013 | British Journal of Haematology2013，160，： | 1 |
| 11 | Maternal Intake of Astaxanthin Improved Hatchability of Fertilized Eggs Stored at High Temperature显示文摘 | Fumiya Saito Kazumi Kita | 2011 | Journal of Pouhry Science2011，48，1： | 1 |
| 12 | Cloning and expression of cDNAs encoding ADP-ribosylation factor in carrot seedling显示文摘 | YUKI A ERIKO I RYUJI S FUMIYA K | 2007 | Plant Science2007，17，2： | 1 |
| 13 | lished and new laboratory Approach of using estab- tests to more comprehen- sively investigate noninfectious and nonhemolytic transfusion reactions-along with the experience in Ja- pan显示文摘 | FUMIYA HIRAYAMA | 2013 | Vox Sang2013，105，： | 1 |
| 14 | Stable Dynamic Walking Over Uneven Terrain 显示文摘 | MANCHESTER Ian R METYIN Uwe LIDA Fumiya | 2011 | The In- ternational Journal of Robotics Research2011，30，2： | 1 |
| 15 | Induction,purification and possible function of chitinase in cultured carrot cells 显示文摘 | FUMIYA K NOBUHIRO T ARASUKE N | 1987 | Physiological and Molecular Plant Patholog''y1987，31，： | 1 |
| 16 | Liposome-encapsulated superoxide dismutase suppresses liposome-mediated augmentation of TNF-α production from peripheral blood leucocytes显示文摘 | Nobuko SF Fumiya H Yoshitaka O | 2001 | Life Sciences2001，69，： | 1 |
| 17 | Stable dynamic walking overuneventerrain显示文摘 | Ian R Manchester Uwe Metin Fumiya Lida | | 0，，03： | 1 |
| 18 | Safe and effective sedation in endoscopic submucosal dissection for early gastric cancer: a randomized comparison between propofol continuous infusion and intermittent midazolam injection显示文摘 | Shinsuke Kiriyama Takuji Gotoda Hiromi Sano Ichiro Oda Fumiya Nishimoto Tetsuro Hirashima Chika Kusano Hiroyuki Kuwano | 2010 | Journal of Gastroenterology2010，，8： | 1 |
| 19 | Composite coating containing WC/12Co cermet and Fe-based metallic glass deposited by high-velocity oxygen fuel spraying显示文摘 | Takeshi Terajima Fumiya Takeuchi Kazuhiro Nakata Shinichiro Adachi Koji Nakashima Takanori Igarashi | 2010 | Journal of Alloys and Compounds2010，，： | 1 |
| 20 | Proposal of a two movers linear oscillatory actuator for active control engine mounts 显示文摘 | FUMIYA K KATSUHIRO H MASAHIKO S | 2013 | IEEE Transactions on Magnetics2013，49，5： | 1 |
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