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51篇 您的检索式:作者名="GALASSO R"
    题名 作者 年代 出处 被引量
1一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P 2014中华神经外科疾病研究杂志2014,13,5:6
2Pancreatic duct replication is increased with obesity and type2 diabetes in humans显示文摘Butler AE Galasso R Matveyenko A 2010Diabetoiogia2010,53,1:1
3The anti -inflammatory cytokine IL - 1Ra protects from high fat diet - induced hyperglycemia显示文摘Sauter NS Schuhhess vr Galasso R 2008Endocrinology2008,149,5:1
4Myocardial expression of FOXO3a-Atrogin-1 pathway in human heart failure显示文摘Galasso G De Rosa R Piscione F 2010Eur J Heart Fail2010,12,12:1
5Clinical evaluation of 209 all- ceramic single crowns cemented on natural and implant -supported abutments with different luting agents: a 6-year retrospective study显示文摘Sorrentino R Galasso L Tet S 2012Clin Implant Dent Relat Res2012,14,2:1
6Hyperinsulinemic hypoglycemia after gastric bypass surgery is not accompaniedby islet hyperplasia or increased β-cell turnover显示文摘Meier JJ Butler AE Galasso R 0,,07:1
7Ultrasonographic examination of the uterine cervix is better than cervical digital examination as a predictor of the likelihood of premature delivery in patients with preterm labor and intact membranes显示文摘Gomez R Galasso M Romero R 1994Am J Obstet Gynecol1994,171,4:1
8The anti-inflammatory cytokine IL-1Ra protects from high fat diet-induced hyperglycemia显示文摘SauterNS Schulthess FT Galasso R 2008Endocrinology2008,149,5:1
9Gynecomastia due to hormone therapy for advanced prostate cancer:a report of ten surgically treated cases and a review of treatment options显示文摘Prezioso D Piccirillo G Galasso R 2004Tumori2004,90,:1
10Everolimus- versus first generation drug-eluting stents: the never-ending story of searching for a winner in the 'limus family' 显示文摘Cassese S Piccolo R Galasso G 2011Int J Cardiol2011,150,2:1
11Not traditional prognostic factors in human conventional renal carcinoma显示文摘Clindolo L Cantile M Galasso R 2001Minerva Urol Nefrol2001,53,4:1
12Long-term safety and effi- cacy of drug-eluting stents in patients with acute myocardial infarc- tion: a meta-analysis of randomized trims 显示文摘Piccolo R Casseses S Galasso G 2011Arthrosclerosis2011,217,1:1
13Ultrasonographic examination of the uterine cervix is better than cervical as a pre- dictor of the likelihood of premature delivery in patients with pretexm labor and intact membranes 显示文摘Gomez R Galasso M Romero R 1994Am J Obstet Gynecol1994,171,4:1
14The value of arnniotic flu- id Interleukin - 6, white blood cell count, and gram stain in the diagnosis of microbial invasion of the amniotic cavity in patients at term显示文摘Gomez R Romero R Galasso M 1994Am J Reprodu Immunol1994,32,3:1
15Prostate cancer treatment and quality of life 显示文摘Prezioso D Galasso R Di Martino M 2007Recent Results Cancer Res2007,175,:1
16PCA3:a new tool to diagnose prostate cancer(PCa) and a guidance in biopsy decisions显示文摘Galasso F Giannella R Bruni P 2010Arch Ital Urol Androl2010,82,1:1
17The anti-inflammatory cytokine interleukin-1 receptor antagonist protects from highfat diet-induced hyperglycemia显示文摘Sauter NS Schulthess FT Galasso R 2008Endocrinology2008,149,5:1
18Prognostic value of p53 and Ki67 expression in fiberoptic bronchial biopsies of patients with non small cell lung cancer显示文摘Ciancio N Galasso M G Campisi R 2012Multidiscip Respir Med2012,7,1:1
19The role of zinc in cerebral ische- mia 显示文摘Galasso S L Dyck R H 2007Mol Med2007,13,78:1
20Modestly increased beta cellapoptosis but no increased beta cell replication in recent-onset type 1 diabetic patients who died of diabetic ketoacidosis显示文摘Butler AE Galasso R Meier JJ 2007Diabetolo-gia2007,50,11:1
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