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| 1 | Management of Helicobacter pylori infection in Latin America: A Delphi technique-based consensus显示文摘AIM: To optimize diagnosis and treatment guidelines for this geographic region, a panel of gastroenterologists, epidemiologists, and basic scientists carried out a structured evaluation of available literature.METHODS: Relevant questions were distributed among the experts, who generated draft statements for consideration by the entire panel. A modified three-round Delphi technique method was used to reach consensus. Critical input was also obtained from representatives of the concerned medical community. The quality of the evidence and level of recommendation supporting each statement was graded according to United States Preventive Services Task Force criteria.RESULTS: A group of ten experts was established. The survey included 15 open-ended questions that were distributed among the experts, who assessed the articles associated with each question. The levels of agreement achieved by the panel were 50% in the first round, 73.3% in the second round and 100% in the third round. Main consensus recommendations included:(1) when available, urea breath and stool antigen test(HpSA) should be used for non-invasive diagnosis;(2) detect and eradicate Helicobacter pylori(H. pylori) in all gastroscopy patients to decrease risk of peptic ulcer disease, prevent o retard progression in patients with preneoplastic lesions, and to prevent recurrence in patients treated for gastric cancer;(3) further investigate implementation issues and health outcomes of H. pylorieradication for primary prevention of gastric cancer in high-risk populations;(4) prescribe standard 14-d triple therapy or sequential therapy for first-line treatment;(5) routinely assess eradication success post-treatment in clinical settings; and(6) select second- and third-line therapies according to antibiotic susceptibility testing.CONCLUSION: These achievable steps toward better region-specific management can be expected to improve clinical health outcomes. | Antonio Rollan Juan Pablo Arab M Constanza Camargo Roberto Candia Paul Harris Catterina Ferreccio Charles S Rabkin Juan Cristóbal Gana Pablo Cortés Rolando Herrero Luisa Durán Apolinaria García Claudio Toledo Alberto Espino Nicole Lustig Alberto Sarfatis Catalina Figueroa Javier Torres Arnoldo Riquelme | 2014 | World Journal of Gastroenterology2014,20,31: | 2 |
| 2 | Kinetics of the acidic and enzymatic hydrolysis of benazepril HCI studied by LC 显示文摘 | GANA M PANDERI I PARISSI-POULOU A | 2002 | J Pharm Biomed Anal2002,27,12: | 1 |
| 3 | Winterhardiness,root physiology and gene expression in successive fall dormancy selections from 'Mesilla'and 'CUF101'alfalfa显示文摘 | CUNNINGAM S M GANA J A VOLENEC J J | 2001 | Crop Sci2001,41,: | 1 |
| 4 | Isolation and characterization of halophilic archaea able to produce bio- surfactants 显示文摘 | Kebbouche G Gana M Khemili S | 2009 | Journal of Industrial Microbiology Biotech- nology2009,36,5: | 1 |
| 5 | Isolation and characterization of halophilic Archaea able to produce biosurfactants显示文摘 | KEBBOUCHE-GANA S GANA M L KHEMILI S | 2009 | Journal of Industrial Microbiol and Biotech2009,36,5: | 1 |
| 6 | Winter hardiness, root physiology,and gene expression in successive fall dormancy selections from ' Mesilla' and ' CUF 101' alfalfa 显示文摘 | CUNNINGHAM S M GANA J A VOLENEC J J | 2001 | Crop Sci2001,,41: | 1 |
| 7 | Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks显示文摘 | Moyal L Lerenthal Y Gana Weisz M | 2011 | Mol Cell2011,41,5: | 1 |
| 8 | Winterhardiness,root physiology and gene expression in successive fall dormancy selections from 'Mesilla' and 'CUF101' alfalfa显示文摘 | Cunningam S M Gana J A Volenec J J | 2001 | Crop Science2001,41,: | 1 |
| 9 | A two-component small multidrug resistance pump functions as a metabolic valve during nicotine catabolism by Arthrobacter nicotinovorans显示文摘 | Ganas P Mihasan M Igloi G L | 2007 | Microbiology2007,153,5: | 1 |
| 10 | Final steps in the catabolism of nicotine - deamination versus demethylation of γ-N-methylaminobutyrate显示文摘 | Chiribau C B Mihasan M Ganas P | 2006 | FEBS J2006,273,: | 1 |
| 11 | Expression of β-amylase from alfalfa taproots显示文摘 | Gana J A Kalengamaliro N E Cunningham S M | 1998 | Plant Physio1998,118,: | 1 |
| 12 | Vrancea slab earthquakes triggered by static stress transfer显示文摘 | Ganas A. Grecu B. Batsi E. Radulian M | 2010 | Natural Hazards and Earth System Science2010,,123: | 1 |
| 13 | Winter hardiness, root physiology, and gene expression in successive fall dormancy selections from 'Mesilla' and 'CUF 101' alfalfa显示文摘 | Cunningham S M Gana J A Volenec J J and Teuber L R | 2001 | Crop science2001,,41: | 1 |
| 14 | Winter hardiness, root physiology, and gene expression in successive fall dormancy selec tions from 'Mesilla' and ' CUF101 'alfalfa 显示文摘 | Cunningham S M Gana J A Volenec J J | 2001 | Crop Sci2001,41,: | 1 |
| 15 | Mi- crostructure and tensile property of the ECAPed pure magnesium 显示文摘 | GANA W M ZHENG M Y CHANG H | 2009 | Journal of Alloys and Compounds2009,470,: | 1 |
| 16 | Winter hardiness, root physiology, and gene expression in successive fall dormancy selections from 'Mesilla' and 'CUF 101' alfalfa显示文摘 | Cunningham S M Gana J A Volenec J J Teuber L R | 2001 | Crop Science2001,41,: | 1 |
| 17 | Winter hardiness,root physiology,and gene expression in successive fall dormancy selections from 'Mesilla' and 'CUF101'alfalfa显示文摘 | Cunningham S M Gana J A Volenec J J | 2001 | Crop Sci2001,41,: | 1 |
| 18 | A two-component small multidrug resistance pump functions as a metabolic valve during nicotine catabolism by Arthrobacter nicotinovorans 显示文摘 | GANAS P MIHASAN M IGLOI G L | 2007 | Microbiology2007,153,5: | 1 |
| 19 | The Ras inhibitor S-trans, trans-famesylthiosalicylic acid chemosensitizes human tumor cells without causing resistance显示文摘 | Gana Weisz M Halaschek Wiener J Jansen B | 2002 | Clin Cancer Res2002,8,2: | 1 |
| 20 | Final steps in the catabolism of nicotine deamination versus demethylation of γ - N - methylaminobutyrate 显示文摘 | CHIRIBAU C B MIHASAN M GANAS P | | FEBS J0,273,: | 1 |