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| 1 | Autophagy regulation by nutrient signaling显示文摘房间的能力在滋养的可获得性对变化作出回应为新陈代谢的动态平衡和生存能力的维护是必要的。对滋养的退却的关键细胞的回答之一是 autophagy 的 upregulation。最近,在那里,在我们分子的机制的知识的快速的扩大涉及了响应关键营养素的弄空感应的哺乳动物的 autophagy 的规定。细胞内部的氨基酸, ATP,和氧层次亲密地被系住到 anabolism 、分解代谢的过程的细胞的平衡。从关键营养素敏感的 kinases mTORC1 和激活安培的蛋白质 kinase (AMPK ) 发信号为 autophagy 小径察觉到的营养素是必要的。最近的进展证明了房间的滋养的地位大部分通过 ULK 和 VPS34 kinase 建筑群的协调规定被传递到 autophagic 机械。在 ULK 和 VPS34 的规定上收敛的广泛的串音和反馈环的鉴定能在 autophagy 正式就职被归因于这些 kinases 的重要性并且维持细胞的动态平衡。 | Ryan C Russell Hai-Xin Yuan Kun-Liang Guan | 2014 | Cell Research2014，24，1： | 69 |
| 2 | YEATS2 是一个选择 histone crotonylation 读者显示文摘 | Dan Zhao Haipeng Guan Shuai Zhao Wenyi Mi Hong Wen Yuanyuan Li Yingming Zhao C David Allis Xiaobing Shi Haitao Li | 2016 | Cell Research2016，26，5： | 9 |
| 3 | Influence of Fe Addition on Products of Self-Propagating High-Temperature Synthesis Reaction in 3Ti-Si-2C System显示文摘Influence of Fe addition on products of self-propagating high-temperature synthesis (SHS) reaction in 3Ti-Si-2C system was investigated in the present study. Without Fe addition, Ti5Si3 and TiC are the dominant phases along with a small amount of Ti3SiC2 phase and unreacted C left in the final products. As Fe content ranges from 10% to 30%, the products consist of TiC, Ti5Si3, Fe2Ti and unreacted C, but no trace of Ti3SiC2 phase is detected. Furthermore, the amounts of both Fe2Ti and C phases increase with Fe content increasing. Addition of Fe has a great effect on the reaction route and significantly restrains the formation of Ti3SiC2 during the combustion synthesis process, and therefore, the SHS is not an effective fabrication technique to synthesize the ternary Ti3SiC2 ceramic in either 3Ti-Si-2C or Fe-3Ti-Si-2C system. Besides, without Fe addition, Ti5Si3 presents as the coarse irregular appearance with an obviously sintered morphology. In contrast, the shape of Ti5Si3 exhibits more and more spherical (cobblestone-like) and the surface becomes increasingly smooth, because the amount of liquids formed during the SHS reaction increases with the increase of Fe content. On the other hand, with Fe content increasing from 0 to 30 wt.%, the particulate size of TiC decreases from more than 5 μm to 1 μm or less, mainly due to the fact that the combustion temperature decreases with the increase of Fe content in the preforms. | Guan Q L Wang H Y Li S L Si W P Jiang Q C | 2009 | 稀有金属材料与工程2009，38，A03： | 2 |
| 4 | Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption 显示文摘 | Guan Y Hao C Cha DR | 2005 | Nat Med2005，11，8： | 1 |
| 5 | A novel anti-inflammatory role for andrographolide in asthma via inhibition of the nuclear factor-kappaB pathway 显示文摘 | Bao Z Guan S Chenq C | 2009 | Am J Respir Crit Care Med2009，179，： | 1 |
| 6 | Chemopreventive effects of alpha - santalol on ultraviolet B radiation - induced skin tumor development in SKH - 1 hairless mice 显示文摘 | Dwivedi C Valluri HB Guan X Agarwal R | 2006 | Carcinogenesis2006，27，9： | 1 |
| 7 | Phase-locked loop techniques a survey显示文摘 | Guan Chyun Hsieh Hung J C | 1996 | IEEE Transactions on Industrial Electronics1996，6，43： | 1 |
| 8 | Embryonic stem cell-derived chondrogenic differentiation in vitro:activation by BMP-2 and BMP-4显示文摘 | HEGERT C GUAN K | 2000 | Mech Dev2000，92，2： | 1 |
| 9 | Multipotential mesenchymal stem cells from femoral bone marrow near the site of osteonecrosis显示文摘 | Guan H Hongsen C | 2001 | J Dent Res2001，80，： | 1 |
| 10 | PPAR gamma regulates adipoeyte cholesterol metabolism via oxidized LDL receptor 1显示文摘 | Chui P C Guan H P Lehrke M | 2005 | Clin Invest2005，115，8： | 1 |
| 11 | Upgrading petroleum residue by two-stage hydrocracking显示文摘 | GUAN C WANG Z QUE G | 2003 | Fuel Processing Technology2003，85，23： | 1 |
| 12 | Reinforcement mechanics of passive bolts in conventional tunneling显示文摘 | GUAN Z C JIANG Y J TANABASI YOSHIHIKO | 2007 | International Journal of Rock Mechanics & Mining Sciences2007，44，4： | 1 |
| 13 | Characterization and degradation behavior of AZ31 alloy surface modified by bone-like hydroxyapatite for implant applications显示文摘 | Wen C L Guan S K Peng L et at | 2009 | Applied Surface Science2009，255，1314： | 1 |
| 14 | High iodine intake is a risk factor of post-partum thyroiditis: result of a survey from Shenyang, China 显示文摘 | Guan H Li C Li Y | 2005 | Journal of Endocrinological Invisti- gation2005，28，87： | 1 |
| 15 | Delay-dependent Guaranteed Cost Control for T-S Fuzzy Systems with Time Delays显示文摘 | Guan X P Chen C L | 2004 | IEEE Trans on Fuzzy Systems2004，12，2： | 1 |
| 16 | Effect of enamel coating on oxidation and hot corrosion resistance of Ti-24Al-14Nb-3V显示文摘 | GUAN C H TANG Z L WANG F H WU W T | 2000 | Chinese J Mater Res2000，14，： | 1 |
| 17 | Embryonic stem cell-derived chondrogenic differentiation in vitro: Activation by BMP-2 and BMP-4显示文摘 | Kramer J Hegert C Guan K | 2000 | Mech Dev2000，92，： | 1 |
| 18 | Identification and characterization of 4-aryl-3,4-dihydropyrimidin-2(1H) ones as inhibitors of the fatty acid transporter FATP4显示文摘 | Blackburn C Guan B Brown J | 2006 | Bioorg Med Chem Lett2006，16，13： | 1 |
| 19 | Molecularly Imprinted Polymer Surfaces as Solid-phase Extraction Sorbents for the Extraction of2-Nitrophenol and Isomers from Environmental Water显示文摘 | Guan W Han C R Wang X | 2012 | J Sep Sci2012，35，49： | 1 |
| 20 | Flow resistance and heat transfer characteristics in micro-cylinders-group显示文摘 | Liu Z G Wang Z L Zhang C W Guan N Jiang G L | | 0，，05： | 1 |
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