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1185篇 您的检索式:作者名="GUAN P"
    题名 作者 年代 出处 被引量
1China Patient-centered Evaluative Assessment of Cardiac Events Prospective Study of Acute Myocardial Infarction: Study Design显示文摘Rachel P Dreyer Xi Li Xue Du Nicholas S Downing Li Li Hai-Bo Zhang Fang Feng Wen-Chi Guan Xiao Xu Shu-Xia Li Zhen-Qiu Lin Frederick A Masoudi John A Spertus Harlan M Krumholz Li-Xin Jiang 2016Chinese Medical Journal2016,,1:13
2Def defines a conserved nucleolar pathway that leads p53 to proteasome-independent degradation显示文摘通过 ubiquitination 小径的 p53 蛋白质周转是在它的 transcriptional 活动的规定的重要机制;然而,很少通过 proteasome 独立的小径对 p53 周转被知道。消化机关扩大因素(Def ) 蛋白质为消化机关的发展是必要的。在 zebrafish, def 的功能的损失有选择地 upregulates p53 反应基因的表示,它提出至于是在 Def 和 p53 之间的关系的一个问题。我们这里报导 Def 是核仁的蛋白质并且 def 的功能的损失导致 p53 蛋白质的 upregulation,它令人惊讶地在 nucleoli 积累。我们的广泛的研究证明了 Def 能调停这个过程是的 p53 蛋白质和那的降级在 Calpain3 的活动独立于 proteasome 小径,却依赖,半胱氨酸朊酶。我们的调查结果定义调整 p53 的周转功能的一条新奇核仁的小径,它将在 organogenesis 和 tumorigenesis 推进我们 p53 的角色的理解。Ting Tao Hui Shi Yihong Guan Delai Huang Ye Chen David P Lane Jun Chen Jinrong Peng 2013Cell Research2013,23,5:8
3Genomic prediction of the performance of hybrids and the combining abilities for line by tester trials in maize显示文摘The two most important activities in maize breeding are the development of inbred lines with high values of general combining ability(GCA)and specific combining ability(SCA),and the identification of hybrids with high yield potentials.Genomic selection(GS)is a promising genomic tool to perform selection on the untested breeding material based on the genomic estimated breeding values estimated from the genomic prediction(GP).In this study,GP analyses were carried out to estimate the performance of hybrids,GCA,and SCA for grain yield(GY)in three maize line-by-tester trials,where all the material was phenotyped in 10 to 11 multiple-location trials and genotyped with a mid-density molecular marker platform.Results showed that the prediction abilities for the performance of hybrids ranged from 0.59 to0.81 across all trials in the model including the additive effect of lines and testers.In the model including both additive and non-additive effects,the prediction abilities for the performance of hybrids were improved and ranged from 0.64 to 0.86 across all trials.The prediction abilities of the GCA for GY were low,ranging between-0.14 and 0.13 across all trials in the model including only inbred lines;the prediction abilities of the GCA for GY were improved and ranged from 0.49 to 0.55 across all trials in the model including both inbred lines and testers,while the prediction abilities of the SCA for GY were negative across all trials.The prediction abilities for GY between testers varied from-0.66 to 0.82;the performance of hybrids between testers is difficult to predict.GS offers the opportunity to predict the performance of new hybrids and the GCA of new inbred lines based on the molecular marker information,the total breeding cost could be reduced dramatically by phenotyping fewer multiple-location trials.Ao Zhang Paulino Pérez-Rodríguez Felix San Vicente Natalia Palacios-Rojas Thanda Dhliwayo Yubo Liu Zhenhai Cui Yuan Guan Hui Wang Hongjian Zheng Michael Olsen Boddupalli M.Prasanna Yanye Ruan Jose Crossa Xuecai Zhang 2022The Crop Journal2022,10,1:3
4Multiple effects of sediment transport and geomorphic processes within flood events: Modelling and understanding显示文摘洪水事件能导致接着影响流动动力学的可观的沉积运输。这研究通过一系列水力的情形,包括的小规模的试验性的案例和照原尺寸的冰川的爆发充满的建模在洪水调查沉积运输的多重效果。一个不一致的、基于层的 morphodynamic 模型被介绍它三个模块的联合是镇静的:一个水动力学模型由包含沉积效果的二维的浅水方程管理了;控制沉积的集体保存的一个沉积运输模型;并且为更新床举起的一个床变丑模型。模型被一个秒顺序 Godunov 类型数字计划解决。通过选择沉积沉重的流动事件的建模,在洪水事件以内的流动和沉积运输和似地球形状的过程的相互作用被阐明。沉积运输增加山峰流动的包括排出,浇水平并且浇在在一张扁平的床上的水坝裂缝流动的深度,这被发现。为一个部分水坝缺口,沉积材料在洪水动力学上有阻塞效果。与 ‘sudden collapse’ 比较一个水坝,一个渐渐的水坝缺口显著地推迟自记水位计同样被改变的山峰流动,和流动的到达时间。可观的床侵蚀和免职发生在快速的爆发洪水以内,它严重地搜索河隧道。洪水繁殖在隧道的大多数区域在沉积运输,和水水平的加入以后被加速,这被注意被减少。Mingfu Guan Nigel G. Wright P, Andrew Sleigh 2015International Journal of Sediment Research2015,30,4:3
5Influence of Fe Addition on Products of Self-Propagating High-Temperature Synthesis Reaction in 3Ti-Si-2C System显示文摘Influence of Fe addition on products of self-propagating high-temperature synthesis (SHS) reaction in 3Ti-Si-2C system was investigated in the present study. Without Fe addition, Ti5Si3 and TiC are the dominant phases along with a small amount of Ti3SiC2 phase and unreacted C left in the final products. As Fe content ranges from 10% to 30%, the products consist of TiC, Ti5Si3, Fe2Ti and unreacted C, but no trace of Ti3SiC2 phase is detected. Furthermore, the amounts of both Fe2Ti and C phases increase with Fe content increasing. Addition of Fe has a great effect on the reaction route and significantly restrains the formation of Ti3SiC2 during the combustion synthesis process, and therefore, the SHS is not an effective fabrication technique to synthesize the ternary Ti3SiC2 ceramic in either 3Ti-Si-2C or Fe-3Ti-Si-2C system. Besides, without Fe addition, Ti5Si3 presents as the coarse irregular appearance with an obviously sintered morphology. In contrast, the shape of Ti5Si3 exhibits more and more spherical (cobblestone-like) and the surface becomes increasingly smooth, because the amount of liquids formed during the SHS reaction increases with the increase of Fe content. On the other hand, with Fe content increasing from 0 to 30 wt.%, the particulate size of TiC decreases from more than 5 μm to 1 μm or less, mainly due to the fact that the combustion temperature decreases with the increase of Fe content in the preforms.Guan Q L Wang H Y Li S L Si W P Jiang Q C 2009稀有金属材料与工程2009,38,A03:2
6Clinical application of retrograde cerebral perfusion for brain protection during surgery of ascending aortic aneurysm--a report of 50 cases显示文摘Dong P Guan Y He M 2002J Extra Corpor Technol2002,34,2:1
7PPAR gamma regulates adipoeyte cholesterol metabolism via oxidized LDL receptor 1显示文摘Chui P C Guan H P Lehrke M 2005Clin Invest2005,115,8:1
8A two-pole 900/ 1800-MHz microstrip filter for dual-band applications显示文摘GUAN X MA Z CAI P 2006Micowave Opt Tech Lett2006,48,7:1
9Preparation and properties of Gd3+ and Y3+ co-doped ceria-based electrolytes for intermediate temperature solid oxide fuel cells 显示文摘GUAN X F ZHOU H P WANG Y N 2008J Alloys Compd2008,464,:1
10Determinants of the decision to submit market or limit orders on the ASX 显示文摘Verhoeven P Ching S Guan H 2004Pacific-Basin Finance Journal2004,12,1:1
11Delay-dependent Guaranteed Cost Control for T-S Fuzzy Systems with Time Delays显示文摘Guan X P Chen C L 2004IEEE Trans on Fuzzy Systems2004,12,2:1
121,3-diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2显示文摘Sui Z Guan J Michael P F 2000Bioorg Med Chem Lett2000,10,6:1
13Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia 显示文摘WANG P GUAN Y F DU H 2012Autophagy2012,8,1:1
14Oxidation behavior and breakdown of an aluminide coating on DZ40M alloy at high temperatures显示文摘Liu P S Liang K M Zhou H Y Guan H R Sun X F Jin T Yang K N 2001Oxidation of Metals2001,55,56:1
15Design, synthesis and preliminary bioactivity studies of 1,3,4-thiadiazole hydroxamic acid derivatives as novel histone deacety-lase inhibitors 显示文摘Guan P Sun F E Hou X B 2012Bioorg Med Chem2012,20,12:1
16显示文摘LANG X GUAN P ZHANG L 2009J Plays Chem C2009,113,10:1
17显示文摘Guan X H Dong X F Ou J P 2007Proc of SPIE2007,6526,65:1
18Expression and significance of FOXM1 in human cervical cancer: a tissue micro-array study显示文摘GUAN P CHEN H LI H J 2011Clin Invest Med2011,34,1:1
19Automatic extraction of lips based on multi- scale wavelet edge detection显示文摘Guan Y P 2008IET Computer Vision2008,2,1:1
20The Corrosion Resistance of Ultra Low Carbon Bainitic Steel 显示文摘Wang Z F Li P H Guan Y 2009Corros Sci2009,51,:1
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