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| 1 | Characterization of the antiviral effects of interferon-α against a SARS-like coronoavirus infection in vitro显示文摘 | Joanna Zorzitto Carole L Galligan Joanna JM Ueng Eleanor N Fish | 2006 | Cell Research2006，16，2： | 3 |
| 2 | High level HIV-1 DNA concentrations in brain tissues differentiate patients with post-HAART AIDS dementia complex or cardiovascular disease from those with AIDS显示文摘Highly active antiretroviral treatment(HAART) has had a significant impact on survival of individuals with acquired immunodeficiency syndrome(AIDS);however,with the longer life-span of patients with AIDS,there is increasing prevalence of AIDS dementia complex(ADC) and other non-AIDS-defining illness,and cardiovascular diseases(CVD) are also common.The influence of these varied disease processes on HIV-1 DNA concentration in brain tissues has not been thoroughly assessed in the post-HAART era.The purpose of the current study is to clarify the impacts of ADC and other complications of HIV disease on the viral load in the brains in AIDS patients with post-HARRT.We examined autopsy specimens from the brains of thirteen patients who died from complications of AIDS with quantitative polymerase chain reaction(QPCR).All but one patient had received HAART prior to death since 1995.Two patients died with severe CVD,multiple cerebrovascular atherosclerosis(CVA) throughout the brain and five patients died with ADC.Six patients had no ADC/CVA.A QPCR was used to measure the presence of HIV-1 DNA in six brain tissues(meninges,frontal grey matter,frontal white matter,temporal subcortex,cerebellum and basal ganglia).In the post-HARRT era,for non-ADC/CVA patients,HIV-1 DNA concentration in brain tissues was statistically higher than that in patients with ADC.In a new finding,two patients who suffered from severe CVD,especially CVA,also had high concentrations of HIV-1 in brain compartments not showing ADC related changes.To our knowledge,this is the first report of a relationship between the CVA and HIV-1 viral burden in brain.The current observations suggest that HAART-resistant HIV reservoirs may survive within ADC lesions of the brain as well as the macrophage rich atherosclerosis,which needs to be confirmed by more AIDS cases with CVA. | GALLIGAN Derek C. LAMERS Susanna L. YU Stephanie SHAGRUN Lamia SALEMI Marco MCGRATH Michael S. | 2009 | Science China(Life Sciences)2009，52，7： | 3 |
| 3 | Political cost incentives for earnings management in the cable television industry显示文摘 | Kimberly Galligan Key | 1997 | Journal of Accounting and Economics1997，，3： | 2 |
| 4 | Laboratory procedures for characterizing manure phosphorus 显示文摘 | Dou Z Toth J D Galligan D T | 2000 | J Environ Qual2000，29，： | 1 |
| 5 | Greedy feature se- lection for glycan chromatography data with the generalized Dirichlet distribution 显示文摘 | Galligan M C Saldova R Campbell M P | 2013 | BMC Bioinformatics2013，14，1： | 1 |
| 6 | The effects of celiac ganglionectomy on sympathetic innervation to the splanchnic organs in the rat 显示文摘 | Li M Galligan J Wang D | 2010 | Auton Neurosci2010，154，12： | 1 |
| 7 | Signalling mechanism coupled to 5-hydroxytryptamine4 receptor- mediated facilitation of fast synaptic transmission in the guinea-pig ileum myenteric plexus显示文摘 | Galligan J J Pan H Messori E | 2003 | Neurogastroenterol Motil2003，15，： | 1 |
| 8 | The role of circulating fibrocytes in inflammation and autoimmunity显示文摘 | Galligan CL Fish EN | 2013 | J Leukoc Biol2013，93，1： | 1 |
| 9 | Increased sympathetic venoconstriction and reactivity to norepinephrine in meaenteric veins in anesthetized DOCA-salt hypertensive rats 显示文摘 | Xu H Fink GD Galligan JJ | 2007 | Am J Physiol Heart Circ Physiol2007，293，： | 1 |
| 10 | 5-hydroxytryptamine, ulcerative colitis, and irritable bowel syndrome: molecular connections显示文摘 | James J Galligan | 2004 | Gastroenterology2004，，7： | 1 |
| 11 | Serum urea nitrogen and conception rate:the usefulness of test information显示文摘 | Ferguson J D Galligan D T Blanchard T Reeves M | 1993 | J Dairy Sci1993，76，12： | 1 |
| 12 | Laboratory procedures for characterizing manure phosphorus显示文摘 | Dou Z Toth J D Galligan D T | 2000 | Journal of Environmental Quality2000，29，： | 1 |
| 13 | Overview of lipid peroxidation products and hepatic protein modification in alcoholic liver disease 显示文摘 | Smathers RL Galligan JJ Stewart BJ | 2011 | Chem Biol Interact2011，192，12： | 1 |
| 14 | Coagulation dysfunction in sepsis and multiple organ system failure显示文摘 | Galligan L Livingstone W Volkov Y | 2003 | Crit Care Clin2003，19，： | 1 |
| 15 | Serum urea nitrogen and conception rate:the usefulness of test information显示文摘 | Ferguson JD Galligan DT Blanchard T | 1993 | Journal of Dairy Science1993，76，： | 1 |
| 16 | Emotional intelligence and psychological resilience to negative life events显示文摘 | Armstrong AR Galligan RF Critchley CR | 2011 | Pers Individ Diff2011，51，3： | 1 |
| 17 | Large-conductance Ca2-acti- vated K channel betal-subunit knockout mice are not hypertensive 显示文摘 | Xu H Garver H Galligan JJ | 2011 | Am J Physiol Heart Circ Physiol2011，300，2： | 1 |
| 18 | Ligand-gated ion channels in the enteric nervous system显示文摘 | Galligan J J | 2002 | Neurogastroenterol Motil2002，14，： | 1 |
| 19 | Sharps injuries and other blood and body fluid exposures among home health care nurses and aides显示文摘 | QUINN MM MARKKANEN PK GALLIGAN CJ | 2009 | Am J Public Health2009，99，3： | 1 |
| 20 | Serum urea ni- trogen and conception rate: The usefulness of test information 显示文摘 | Ferguson J D Galligan D T Blanchard T | 1993 | J Dairy Sci1993，76，： | 1 |
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