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| 1 | NG2 Cell Response in the CNP-EGFP Mouse After Contusive Spinal Cord Injury显示文摘成年动物中枢神经系统中的NG2细胞具有异质性。脊髓损伤(SCI)后,具有少突胶质前体细胞(OPCs)功能的NG2细胞亚型如何产生反应性变化及对其正常的发育过程有何影响目前还不清楚。本文采用少突胶质细胞系细胞表达EGFP的CNP-EGFP小鼠,研究正常和SCI后的NG2细胞的特征。在正常小鼠的白质中,对EGFP+NG2+双极细胞和EGFPnegNG2+多极细胞进行鉴别。SCI后,白质损伤边缘区中的EGFP+NG2+细胞3 d增殖达高峰,损伤中心区的EGFPnegNG2+细胞增殖在损伤后7 d达高峰。损伤后EGFP+NG2+细胞的Olig2、Sox10、Sox17等转录因子、基本的膜电生理参数以及钾电流表型均与发育过程增殖的OPCs一致。EGFPnegNG2+细胞不表达少突胶质发生中的转录因子。EGFP+CC1+少突胶质细胞6周时包含在EGFP+NG2+细胞增殖峰时表达BrdU的细胞。EGFPnegCC1+少突胶质细胞未被观察到。神经胶质生长因子2和成纤维细胞生长因子2处理促进少突胶质发生,提高EGFPnegNG2+细胞数量。因此,通过EGFP和转录因子表达,时空增殖类型及对生长因子的反应,两种类型的NG2+细胞对SCI刺激发生反应。SCI后EGFP+NG2+细胞经受细胞和生理变化特征,与在早期出生后的少突胶质发生过程中NG2+细胞中的变化类似。 | JUDITH M LYTLE RAMESH CHITTAJALLU JEAN R WRATHALL VITTORIO GALLO | 2009 | 神经损伤与功能重建2009，4，1： | 7 |
| 2 | Optimized Formulation of Magnetic Chitosan Microspheres Containing the Anticancer Agent显示文摘 | Hassan F F Parish R C Gallo J M | 1992 | Oxantrazole Pharm Res1992，9，3： | 2 |
| 3 | Selective in vitro growth of T lymphocytes from normal human bone marrows显示文摘 | Morgan D A Ruscetti F W Gallo R | 1976 | Science1976，193，4257： | 1 |
| 4 | Physiopathology of acute coronary syndromes显示文摘 | Quilici J Gallo R | 1999 | Ann Cardiol Angeiol (Paris)1999，48，910： | 1 |
| 5 | Improvement in establishing the peptoid of rubella primary virus infection using a mild protein denaturant显示文摘 | Condorelli F Stivala A Gallo R | 1997 | J Virol Methods1997，66，1： | 1 |
| 6 | Inhibition of intimal thickening after balloon angioplasty in porcine coronary arleries by targeting regulators of the cell cycle 显示文摘 | Gallo R Padurean A Jayaraman T | 1999 | Circulation1999，99，16： | 1 |
| 7 | Stress field translation in the healthy human temporomandibular joint 显示文摘 | Gallo L M Nickel J C Iwasaki L R | 2000 | J Dent Res2000，79，10： | 1 |
| 8 | Overlapping functions of ABC transporters in topotecan disposition as determined in gene knockout mouse models显示文摘 | Tiwari AK Zhang R Gallo JM | 2013 | Mol Cancer Ther2013，1，30： | 1 |
| 9 | Identification of critical residues of the MyD88 death domain involved in the recruitment of downstream kinases 显示文摘 | Loiarro M Gallo G Desantis R | 2009 | J Biol Chem2009，284，28： | 1 |
| 10 | Ultrasono- graphic bone characteristics during normal pregnancy: longitudinal and cross-sectional evaluation显示文摘 | Gamhacciani M Spinetti A Gallo R | 1995 | Am J Obstet Gynecol1995，173，31： | 1 |
| 11 | The use of a vegetation index for assessment of the urban heat island effect 显示文摘 | Gallo K P L Mcnab A Karl T R | 1993 | Int J Remote Serving1993，14，11： | 1 |
| 12 | Selectibe vitrogrouth of Lymphocytes from normal human bome marrows显示文摘 | Morgam DA Rusceff FW Gallo R | 1976 | Science1976，193，： | 1 |
| 13 | The Influ- ence of Land Use/Land cover on Climatological Values of the Diur- nal Temperature Range 显示文摘 | Kevin P Gallo David R Easterling Thomas C Pesterson | 1996 | Journal of Climate1996，，： | 1 |
| 14 | AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense显示文摘 | Lai Y P Gallo R L | 2009 | Trends in Immunology2009，30，3： | 1 |
| 15 | Obestatin promotes survival of pancreatic β-cells and human islets and induces expression of genes involved in the regulation of β-cell mass and function显示文摘 | Granata R Settanni F Gallo D | 2008 | Diabetes2008，57，4： | 1 |
| 16 | A new expandable intracoronary tantalum (Strecker) stent:Early experimental results and follow-up to twelve months显示文摘 | Ribeiro P A Gallo R Antonius J | 1993 | Am Heart J1993，125，2： | 1 |
| 17 | Media optimization for maximum biomass production in cell cultures of pacific yew显示文摘 | Ketchum R E B Gibson D M Gallo L G | 1995 | Plant Cell Tissue and Organ Culture1995，42，2： | 1 |
| 18 | Pressurized liquid extraction for the determination of polyphenols in apple显示文摘 | ALONSO-SALCES R M KORTA E BARRANCO A BERRUETA L A GALLO B VICENTE F | 2001 | Journal of Chromatography A2001，933，1： | 1 |
| 19 | Two-incision technique for treatment of complex proximal humerus fractures显示文摘 | Gallo R A Zeiders G J Altman G T | 2005 | J Orthop Trau- ma2005，19，10： | 1 |
| 20 | Envi- ronmental degradation of isotactic polypropylene plates as studied by positron annihilation lifetime spectroscopy 显示文摘 | BRAMBILLA L CONSOLATI G GALLO R | 2003 | Polymer2003，44，4： | 1 |
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