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| 1 | Microstructural evolution and mechanical properties of FeCoCrNiCu high entropy alloys:a microstructure-based constitutive model and a molecular dynamics simulation study显示文摘High entropy alloys(HEAs)attract remarkable attention due to the excellent mechanical performance.However,the origins of their high strength and toughness compared with those of the traditional alloys are still hardly revealed.Here,using a microstructure-based constitutive model and molecular dynamics(MD)simulation,we investigate the unique mechanical behavior and microstructure evolution of FeCoCrNiCu HEAs during the indentation.Due to the interaction between the dislocation and solution,the high dislocation density in FeCoCrNiCu leads to strong work hardening.Plentiful slip systems are stimulated,leading to the good plasticity of FeCoCrNiCu.The plastic deformation of FeCoCrNiCu is basically affected by the motion of dislocation loops.The prismatic dislocation loops inside FeCoCrNiCu are formed by the dislocations with the Burgers vectors of a/6[112]and a/6[112],which interact with each other,and then emit along the<111>slip direction.In addition,the mechanical properties of FeCoCrNiCu HEA can be predicted by constructing the microstructure-based constitutive model,which is identified according to the evolution of the dislocation density and the stress-strain curve.Strong dislocation strengthening and remarkable lattice distortion strengthening occur in the deformation process of FeCoCrNiCu,and improve the strength.Therefore,the origins of high strength and high toughness in FeCoCrNiCu HEAs come from lattice distortion strengthening and the more activable slip systems compared with Cu.These results accelerate the discovery of HEAs with excellent mechanical properties,and provide a valuable reference for the industrial application of HEAs. | Gangjie LUO Li LI Qihong FANG Jia LI Yuanyuan TIAN Yong LIU Bin LIU Jing PENG P.K.LIAW | 2021 | Applied Mathematics and Mechanics(English Edition)2021，42，8： | 3 |
| 2 | Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells显示文摘 | Gangji MD Jean-Philippe | 2004 | J Bone Joint Sury(Am)2004，66，2： | 1 |
| 3 | Urenmic bleeding:pathophysiology and clinical risk factors 显示文摘 | Sohal A S Gangji A S Growther M A | 2006 | Thromb Res2006，118，3： | 1 |
| 4 | Association betweenNterminal propeptide B-type natriuretic peptide and markers ofhypervolemia显示文摘 | Gangji A S Helal B A Churchill D N | 2008 | Perit Dial Int2008，28，3： | 1 |
| 5 | Autologous bone mar- row cell implantation in the treatrrcnt of non = traumatic osteone- crosis of the femoral head: Five year follow -up of a prospective controlled study显示文摘 | Gangji V De Maertelaer V Hauzeur JP | 2011 | Bone2011，49，5： | 1 |
| 6 | Interleukin-6 with its soluble receptor enhances the expression of insulin-like growth factor-1 in osteoblasts显示文摘 | Gangji V Durant D | 1997 | Endocrinology1997，138，： | 1 |
| 7 | Autologous bone marrow cel implantation in the treatment of non-traumatic osteonecrosis of the femoral head:Five year fol ow-up of a prospective control ed study显示文摘 | Gangji V De Maertelaer V Hauzeur JP | | 0，，05： | 1 |
| 8 | Mercury-associated nephritic syndrome:a case report and systematic review of the literature显示文摘 | MILLER S PALLAN S GANGJI A S | 2013 | Am J Kidney Dis2013，62，1： | 1 |
| 9 | Abnormalities in the replicative capacity of osteoblasitic cells in the proximal femur of patients with osteonecrosis of the femoral head显示文摘 | Gangji V Hauzeur JP Schoutens A | 2003 | J Rheumatol2003，30，2： | 1 |
| 10 | Abnormalities in the replicative capacity of osteoblastic cells in the proximal femur of patients with osteonecrosis of the femoral head显示文摘 | Gangji V Hauzeur JP Scboutens A et a1 | 2003 | J Rhenmatol2003，30，2： | 1 |
| 11 | Stem cell therapy for osteone- crosis of the femoral head显示文摘 | Gangji V Toungouz M Hauzeur J P | 2005 | Expert Opin Biol Ther2005，5，4： | 1 |
| 12 | A systematic review and meta-analysis of hypoglycemia and cardiovascular events:a comparison of glyburide with other secretagogues and with insulin显示文摘 | Gangji AS Cukierman T Gerstein HC | | 0，，： | 1 |
| 13 | Autologous bone marrow cell implantation in the treatment of non-traumatic osteonecrosis of the femoral head: Five year follow-up of a prospective controlled study显示文摘 | Valérie Gangji Viviane De Maertelaer Jean-Philippe Hauzeur | 2011 | Bone2011，，5： | 1 |
| 14 | Efficacy and safety of non-vitamin K antagonist oral anticoagulants post-kidney transplantation显示文摘BACKGROUND Novel oral anticoagulants(NOACs)were developed as alternatives to vitamin K antagonists,primarily warfarin,as they do not require routine monitoring and have limited drug-drug and drug-food interactions.However,the efficacy and safety of these agents in kidney transplantation are not well studied.AIM To assess the profile and safety of NOACs for patients who had kidney transplantation,and to provide recommendations and guidelines on therapeutic strategies in these patients.METHODS This was a retrospective study carried out among adult patients who were actively on the following NOACs(apixaban,rivaroxaban or dabigatran)in our renal transplantation program from December 2015 to December 2016.The patients were identified primarily through electronic medical record system(patient data linkage).Data on the clinical and laboratory profile of the patients were retrieved and analyzed with SPSS 22.0.RESULTS Complete data on 42 renal transplant patients were retrieved:59.5%males,90.5%were whites and 66.7%were older than 60 years old.The mean duration since renal transplantation of the patients was 8.8±7.4 years.The most common risk factors for the development of end-stage renal disease in the subjects were hypertension(19.0%),polycystic kidney disease(19.0%),followed by diabetic nephropathy(16.7%)and chronic glomerulonephritis(16.7%).The main indications for NOACs use in the cohort were atrial fibrillation in 25 patients(59.5%)and venous thromboembolism in 10 patients(23.8%).Overall,29 patients(69%)were treated with apixaban,10 patients(23.8%)with rivaroxaban and 3 patients(7.14%)with dabigatran.No(0%)thromboembolic events were observed during the one-year period,but 3(7.1%)bleeding events occurred in the cohort consisting of 1 patient treated with rivaroxaban 15 mg daily and 2 patients who received apixaban 2.5 mg twice daily.There were no significant changes in serum tacrolimus level three days after the initiation of NOACs among patients treated with tacrolimus(pre-and post-NOACs tacrolimus levels were 7.2516 and 7.8867 ng/m L,P=0.55,respectively).Also,after one-year of treatment with NOACs there were no significant changes in the pre-and post-NOACs serum creatinine level(P=0.772)and estimated glomerular filtration rates(P=0.232).CONCLUSION No thromboembolic events or significant changes in renal profile were observed in our cohort of kidney transplant recipients who were treated with NOACs for at least a year.However,a few bleeding events were observed.This calls for further well-planned randomized controlled trials to assess the efficacy and safety of NOACs among renal transplant recipients. | Muhammad A Bukhari Abdulrahman Al-Theaby Mohammed Tawhari Ali Al-Shaggag Ryan Pyrke Azim Gangji Darin Treleaven Christine Ribic | 2019 | World Journal of Transplantation2019，9，6： | 1 |
| 15 | Abnormalities in the replicative capacity of osteoblastic cells in the proximal femur of patients with osteonecrosis of the femoral head显示文摘 | GANGJI V HAUZEUR JP SCHOUTENS A etal | 2003 | J Rheumatol2003，30，2： | 1 |
| 16 | Stem cell therapy for osteonecrosis of the femoral head显示文摘 | Gangji V Toungouz M Hauzeur JP | | 0，，4： | 1 |
| 17 | Treatment of osteonecrosis of the femoral head with implantation of autologous bone-man'ow cells: a pilot study 显示文摘 | GANGJI V HANUZEUR J P MATOS C | 2004 | J Bone Joint Surg(AM)2004，86，6： | 1 |
| 18 | Insulin-like growth factor II premotor expression in cultured rodent osteoblasts and adult rat bone显示文摘 | Gangji V Rydziel S Gabbitas B | 1998 | Endocrinology1998，139，5： | 1 |
| 19 | Insulin-like growth factor Ⅱ promoter expression in cultured rodent osteoblast and adult rat bone显示文摘 | Gangji V Rydziel S Gabbitas B | 1998 | Endocrinology1998，139，： | 1 |
| 20 | Stem cell therapy for osteonecrosis of the femoral head 显示文摘 | Gangji V Toungouz M Hauzeur JP | 2005 | Expert Opin Biol Ther2005，4，： | 1 |
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