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| 1 | Role of the endothelium in inflammatory bowel diseases显示文摘Inflammatory bowel diseases(IBD) are a complex group of diseases involving alterations in mucosal immunity and gastrointestinal physiology during both initiation and progressive phases of the disease.At the core of these alterations are endothelial cells,whose continual adjustments in structure and function coordinate vascular supply,immune cell emigration,and regulation of the tissue environment.Expansion of the endothelium in IBD(angiogenesis),mediated by inflammatory growth factors,cytokines and chemokines,is a hallmark of active gut disease and is closely related to disease severity.The endothelium in newly formed or inflamed vessels differs from that in normal vessels in the production of and response to inflammatory cytokines,growth factors,and adhesion molecules,altering coagulant capacity,barrier function and blood cell recruitment in injury.This review examines the roles of the endothelium in the initiation and propagation of IBD pathology and distinctive features of the intestinal endothelium contributing to these conditions. | Walter E Cromer J Michael Mathis Daniel N Granger Ganta V Chaitanya J Steven Alexander | 2011 | World Journal of Gastroenterology2011，17，5： | 10 |
| 2 | BK nephropathy in the native kidneys of patients with organ transplants: Clinical spectrum of BK infection显示文摘Nephropathy secondary to BK virus, a member of the Papoviridae family of viruses, has been recognized for some time as an important cause of allograft dysfunction in renal transplant recipients. In recent times, BK nephropathy(BKN) of the native kidneys has being increasingly recognized as a cause of chronic kidney disease in patients with solid organ transplants, bone marrow transplants and in patients with other clinical entities associated with immunosuppression. In such patients renal dysfunction is often attributed to other factors including nephrotoxicity of medications used to prevent rejection of the transplanted organs. Renal biopsy is required for the diagnosis of BKN. Quantitation of the BK viral load in blood and urine are surrogate diagnostic methods. The treatment of BKN is based on reduction of the immunosuppressive medications. Several compounds have shown antiviral activity, but have not consistently shown to have beneficial effects in BKN. In addition to BKN, BK viral infection can cause severe urinary bladder cystitis, ureteritis and urinary tract obstruction as well as manifestations in other organ systems including the central nervous system, the respiratory system, the gastrointestinal system and the hematopoietic system. BK viral infection has also been implicated in tumorigenesis. The spectrum of clinical manifestations from BK infection and infection from other members of the Papoviridae family is widening. Prevention and treatment of BK infection and infections from other Papovaviruses are subjects of intense research. | Darlene Vigil Nikifor K Konstantinov Marc Barry Antonia M Harford Karen S Servilla Young Ho Kim Yijuan Sun Kavitha Ganta Antonios H Tzamaloukas | 2016 | World Journal of Transplantation2016，6，3： | 4 |
| 3 | Prolonged hypernatremia triggered by hyperglycemic hyperosmolar state with coma: A case report显示文摘A man with past lithium use for more than 15 years, but off lithium for two years and not carrying the diagnosis of diabetes mellitus or nephrogenic diabetes insipidus(NDI), presented with coma and hyperglycemic hyperosmolar state(HHS). Following correction of HHS, he developed persistent hypernatremia accompanied by large volumes of urine with low osmolality and no response to desmopressin injections. Urine osmolality remained < 300 m Osm/kg after injection of vasopressin. Improvement in serum sodium concentration followed the intake of large volumes of water plus administration of amiloride and hydrochlorothiazide. Severe hyperglycemia may trigger symptomatic lithium-induced NDI years after cessation of lithium therapy. Patients with newonset diabetes mellitus who had been on prolonged lithium therapy in the past require monitoring of their serum sodium concentration after hyperglycemic episodes regardless of whether they do or do not carry the diagnosis of NDI. | Darlene Vigil Kavitha Ganta Yijuan Sun RichardⅠDorin Antonios H Tzamaloukas Karen S Servilla | 2015 | World Journal of Nephrology2015，4，2： | 3 |
| 4 | Nanofat: A therapeutic paradigm in regenerative medicine显示文摘Adipose tissue is a compact and well-organized tissue containing a heterogeneous cellular population of progenitor cells,including mesenchymal stromal cells.Due to its availability and accessibility,adipose tissue is considered a“stem cell depot.”Adipose tissue products possess anti-inflammatory,anti-fibrotic,antiapoptotic,and immunomodulatory effects.Nanofat,being a compact bundle of stem cells with regenerative and tissue remodeling potential,has potential in translational and regenerative medicine.Considering the wide range of applicability of its reconstructive and regenerative potential,the applications of nanofat can be used in various disciplines.Nanofat behaves on the line of adipose tissuederived mesenchymal stromal cells.At the site of injury,these stromal cells initiate a site-specific reparative response comprised of remodeling of the extracellular matrix,enhanced and sustained angiogenesis,and immune system modulation.These properties of stromal cells provide a platform for the usage of regenerative medicine principles in curbing various diseases.Details about nanofat,including various preparation methods,characterization,delivery methods,evidence on practical applications,and ethical concerns are included in this review.However,appropriate guidelines and preparation protocols for its optimal use in a wide range of clinical applications have yet to be standardized. | Madhan Jeyaraman Sathish Muthu Shilpa Sharma Charan Ganta Rajni Ranjan Saurabh Kumar Jha | 2021 | World Journal of Stem Cells2021，13，11： | 2 |
| 5 | Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells显示文摘 | GANTA S AMIJI M | 2009 | Mol Pharm2009，6，3： | 1 |
| 6 | Aseorbic acid alters collagen integrins in bone euhure 显示文摘 | Ganta DR McCarthy MB Gronowicz GA | 1997 | Endocrinology1997，138，9： | 1 |
| 7 | Isolated dysphagia after asmall posterolateral medullary infarct: a case report 显示文摘 | Zand R Ganta K Afshani M | 2012 | Can J Neurol Sci2012，39，3： | 1 |
| 8 | Role of integrated canc- er nanomedicine in overcoming drug resistance显示文摘 | IYER AK SINGH A GANTA S | 2013 | Adv Drug De- liv Rev2013，65，1314： | 1 |
| 9 | Laparoscopic-as-sisted colon resections:olng-term results and survival显示文摘 | Mehta pp Giffin J Ganta S | 2005 | JSLS2005，9，2： | 1 |
| 10 | The role of single serum progesterone measurement in conjunction with beta hCG in the management of suspected ectopic pregnancy显示文摘 | El Bishry G Ganta S | 2008 | J Obstet Gynaecol2008，28，4： | 1 |
| 11 | Laparoscopic- as- sisted colon resections long-term results and survival 显示文摘 | MEHTA P P GRIFFIN J GANTA S | 2005 | JSLS2005，，9： | 1 |
| 12 | Coadministration of paclitaxel and curcu?min in nanoemulsion formulations to overcome multidrug resist?ance in tumor cells显示文摘 | GANTA S AMUI M | 2009 | Mol Pharm2009，6，3： | 1 |
| 13 | A review of stimuli-responsive nanocarriers for drug and gene delivery 显示文摘 | Ganta S Devalapally H Shahiwala A | 2008 | Jour- nal of Controlled Release2008，126，3： | 1 |
| 14 | Central angiotensin Ⅱ-enhanced splenic cytokine gene expression is mediated by the sympathetic nervous system显示文摘 | Ganta CK Lu N Helwig BG | | 0，，04： | 1 |
| 15 | Curcum inphospholipid complex : preparation, therapeutic evaluation and pharmacokinetic study in r2ts 显示文摘 | ITIK MA MUKHERJEEK GANTA IT | 2007 | Int J Pharm2007，330，： | 1 |
| 16 | Rat umbilical cord stem cells completely abolish rat mammary carcinomas with no evidence of metastasis or recurrence 100 days post-tumor cell inoculation显示文摘 | Ganta C Chiyo D Ayuzawa R | 2009 | Cancer Res2009，69，5： | 1 |
| 17 | Laparoscopic-assisted colon resections:long-term results and survival显示文摘 | Mehta PP Griffin J Ganta S | 2005 | JSLS2005，9，2： | 1 |
| 18 | VEGF-A isoform modulation in an preclinical TNBS model of ulcerative colitis: protective effects ofa VEGF164b therapy 显示文摘 | Walter E Cromer Chaitanya V Ganta Mihir Patel | 2013 | J Transl Med2013，11，11： | 1 |
| 19 | Laparoscopic-assisted colon resections:long-term results and survival显示文摘 | Mehta PP Griffin J Ganta S | 2005 | JSLS2005，9，： | 1 |
| 20 | The role of single serum progesterone measurement in conjunction with beta hCG in the management of suspected ectopic pregnancy显示文摘 | El Bishty G Ganta S | 2008 | J Obstet Gynaecol2008，28，4： | 1 |
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