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| 1 | Corrosion Behavior of Cupronickel Alloy in Simulated Seawater in the Presence of Sulfate-Reducing Bacteria显示文摘The corrosion behavior of cupronickel alloy immersed in the simulated seawater in or without the presence of sulfate-reducing bacteria(SRB)was studied.The results of scanning electronic microscopy and electrochemical impedance spectra reveal that corrosion of the sample immersed in the simulated seawater with SRB was more serious than that immersed in the simulated seawater without SRB.The atomic force microscopy images show that after immersion for 15 days,the surface roughness of the sample in the simulated seawater with SRB was higher than that of the sample in the simulated seawater without SRB.The analysis of confocal laser scanning microscopy indicates that the average depth of the pits on the surface of the sample in the simulated seawater with SRB was almost twice deeper than that of the sample in the simulated seawater without SRB. | Yanyan Song Hongwei Shi Jun Wang Fuchun Liu En-Hou Han Wei Ke Ganxin Jie Jun Wang Haijun Huang | 2017 | Acta Metallurgica Sinica(English Letters)2017，30，12： | 2 |
| 2 | Electrocardiographic T Wave: A Symbol of Transmural Dispersion of Repolarization in the Ventricles显示文摘 | Ganxin Yah Jack Martin | 2003 | Journal of Cardiovascular Electrophysiology2003，14，6： | 1 |
| 3 | J Wave Syndrome 显示文摘 | Antzeleviteh C YAN Ganxin | 2010 | Heart Rhythm2010，7，： | 1 |
| 4 | Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation 显示文摘 | GANXIN YAN CHARLES ANTZELEVITCH | 1999 | Circulation1999，100，： | 1 |
| 5 | A new intumescent flame retardant containing phosphorus and nitrogen: Preparation, thermal properties and application to UV curable coating显示文摘 | Lijuan Chen Lei Song Pin Lv Ganxin Jie Qilong Tai Weiyi Xing Yuan Hu | 2010 | Progress in Organic Coatings2010，，： | 1 |
| 6 | Chrombismite (Bi16CrO27),a new mineral from shaanxi province, China显示文摘 | Yan Jincai Wang Ganxin | 1997 | The Canadian mineralogist1997，135，1： | 1 |
| 7 | J Weve Syndrome Heart显示文摘 | ANTZELEVITCH C YAN GANXIN | 2010 | Rhythm2010，7，： | 1 |
| 8 | Flame retardancy andthermal degradation of cotton textiles based on UV-curable flame retardant coatings 显示文摘 | Weiyi Xing Ganxin Jie | 2011 | Thermochimica Acta2011，513，： | 1 |
| 9 | A symbol of transmural dispersion of repolari zation in the ventricles显示文摘 | Ganxin Y Jack M Eletrocardiographic T | 2003 | Journal of Cardiovascular Electrophysiology2003，14，6： | 1 |
| 10 | J Wave Syndrome 显示文摘 | Antzelevitch C YAN Ganxin | 2010 | Heart Rhythm2010，7，： | 1 |
| 11 | Electrocardiographic T Wave: A symbol of trans- mural dispersion of repelarization in the ventricles 显示文摘 | Yan Ganxin Martin J | 2003 | Cardiovascular Electrophysiology2003，14，6： | 1 |
| 12 | Electrocardiographic T Wave:A Symbol of Transmural Dispersion of Repolarization in the Ventricles显示文摘 | Ganxin Yan Martin J | | 0，，05： | 1 |
| 13 | Flame retardancy and thermal degradation mechanism of epoxy resin composites based on a DOPO substituted organophosphorus oligomer显示文摘 | Xin Wang Yuan Hu Lei Song Weiyi Xing Hongdian Lu Pin Lv Ganxin Jie | 2010 | Polymer2010，，11： | 1 |
| 14 | chrombismite (Bi16Cr027),a new mineral from shanxi province, china显示文摘 | Zhou Xinchun Yan jincai Wang Ganxin | 1997 | the Canadian mineralalogist1997，35，1： | 1 |
| 15 | Flame retardancy and thermal degradation mechanism of epoxy resin composites based on a DOPO substituted organophosphorus oligomer显示文摘 | Xin Wang Yuan Hu Lei Song Weiyi Xing Hongdian Lu Pin Lv Ganxin Jie | 2010 | Polymer2010，，11： | 1 |
| 16 | Electrocardiographic T Wave:A Symbol of Transmural Dispersion of Repolarization in the Ventricles显示文摘 | Ganxin Yan Jack Martin | 2003 | Jourual of Cardiovascular Electrophysiology2003，14，6： | 1 |
| 17 | Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome 显示文摘 | Yah Ganxin Antzelevitch C | 1998 | Circulation1998，98，： | 1 |
| 18 | Electrocardiographic T Wave: A Symbol of Trans- mural Dispersion of Repolarization in the Ventricles显示文摘 | Ganxin Yan Martin J | 2003 | 14(5):639 -6402003，14，5： | 1 |
| 19 | Xiaoaiping injection affects the invasionand metastasis of hepatocellular carcinomaby controlling AFP expression显示文摘Objective Xiaoaiping (XAP) is a traditional Chinese medicine that is a commonly used as an anticancerdrug in clinical practice owing to its high efficiency and low toxicity. Specifically, XAP can effectively inhibitthe growth of hepatocellular carcinoma (HCC). Alpha-fetoprotein (AFP) is a key HCC diagnostic marker andis closely related to certain malignant cytological behaviors of HCC. However, whether AFP expression andXAP treatment are related to the invasion and metastasis of HCC remains unclear. In the present study, weaimed to evaluate the effects and underlying mechanism of XAP on the invasion and metastasis of HCC..Methods Using a cell scratch assay, Transwell technology, and western blotting we detected the differentinvasion and metastatic abilities of Hep3B cells in XAP treatment and blank control groups. This allowedcomparison of the invasion and metastatic abilities of Hep3B cells with differing levels of AFP expression.AFP mRNA sequencing technology was used to analyze the mechanism of tumor invasion and metastasisassociated with AFP and XAP treatment.Results Cell invasion and metastasis abilities in the XAP group were significantly lower than those in thecontrol group (P < 0.05). Additionally, compared to the control group, the expression of AFP significantlydecreased after XAP treatment (P < 0.05). The ability of Hep3B cells to invade and metastasize waspromoted when AFP expression was up-regulated, whereas it was inhibited when AFP was silenced. XAPinjection and AFP regulate the invasion and metastatic ability of HCC by affecting matrix metalloproteinases(MMPs).Conclusion XAP injection inhibits the invasion and metastatic ability of HCC by influencing the expressionof AFP;additionally, this inhibition of AFP is achieved by affecting MMPs. | Shu Huang Ganxin Wang | 2023 | Oncology and Translational Medicine2023，9，1： | 0 |
| 20 | Prognostic role of plasma levels ofγ-glutamyl transpeptidase in patients with advanced gastric cancer treated with anti-PD-1 immunotherapy显示文摘Objective Antibodies targeting programmed cell death protein 1(PD-1)have become the mainstay of treatment for chemotherapy-refractory gastric cancer,characterized by high levels of programmed cell death ligand-1(PDL-1)expression.However,the routine clinical implementation of PDL-1 testing is currently limited by the lack of robust detection methods.In this regard,the role of plasmaγ-glutamyl transpeptidase(GGT),an N-terminal nucleophilic hydrolase,as an independent predictor of the efficacy of anti-PD-1 therapy remains unknown.In this study,we aimed to assessed the prognostic role of changes in plasma GGT levels(6 weeks vs.baseline)in patients with advanced gastric cancer treated with anti-PD-1 immunotherapy.Methods We retrospectively analyzed data from 57 patients with gastric cancer treated with anti-PD-1 antibodies(camrelizumab,sintilimab,nivolumab,tislelizumab,and toripalimab)at the Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,China,from July 2018 to February 2021.Results We found that after 6 weeks of treatment,there were significant differences between responders and non-responders with respect to plasma GGT levels(P<0.001).Multivariate logistic regression analysis revealed that the continuous value of the 6-week difference in GGT levels(OR=1.437,95%CI=1.116-1.849,P=0.005)and 6-week difference in GGT≥0 or<0(OR=53.675,95%CI=6.379-451.669,P<0.001)were independent predictors of disease control.Survival analysis indicated that a reduction in plasma GGT6 levels during treatment was significantly associated with a favorable progression-free survival(PFS)and overall survival(P<0.001).Consistently,univariate and multivariate Cox regression analyses revealed that a reduction in plasma GGT6 levels during treatment was an independent predictor of PFS(HR=1.033,95%CI=1.013-1.053,P=0.001).Conclusion Alterations in plasma GGT levels during treatment can be used as a predictor of disease progression and survival in patients with advanced gastric cancer undergoing treatment with anti-PD-1 antibodies. | Shaojie Xu Yiming Feng Xingyin Li Zaozao Huang Hewei Li Ganxin Wang | 2022 | Oncology and Translational Medicine2022，8，3： | 0 |
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