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9篇 您的检索式：作者名="Garella S"

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		题名	作者	年代	出处	被引量
	1	Adiponectin affects the mechanical responses in strips from the mouse gastric fundus显示文摘AIM To investigate whether the adipocytes derived hormone adiponectin(ADPN) affects the mechanical responses in strips from the mouse gastric fundus. METHODS For functional experiments, gastric strips from the fundal region were cut in the direction of the longitudinal muscle layer and placed in organ baths containing KrebsHenseleit solution. Mechanical responses were recorded via force-displacement transducers, which were coupled to a polygraph for continuous recording of isometric tension. Electrical field stimulation(EFS) was applied via two platinum wire rings through which the preparation was threaded. The effects of ADPN were investigated on the neurally-induced contractile and relaxant responses elicited by EFS. The expression of ADPN receptors, Adipo-R1 and Adipo-R2, was also evaluated by touchdown-PCR analysis. RESULTS In the functional experiments, EFS(4-16 Hz) elicited tetrodotoxin(TTX)-sensitive contractile responses. Addition of ADPN to the bath medium caused a reduction in amplitude of the neurally-induced contractile responses(P < 0.05). The effects of ADPN were no longer observed in the presence of the nitric oxide(NO) synthesis inhibitor L-NG-nitro arginine(L-NNA)(P > 0.05). The direct smooth muscle response to methacholine was not influenced by ADPN(P > 0.05). In carbachol precontracted strips and in the presence of guanethidine, EFS induced relaxant responses. Addition of ADPN to the bath medium, other than causing a slight and progressive decay of the basal tension, increased the amplitude of the neurally-induced relaxant responses(P < 0.05). Touchdown-PCR analysis revealed the expression of both Adipo-R1 and Adipo-R2 in the gastric fundus.CONCLUSION The results indicate for the first time that ADPN is able to influence the mechanical responses in strips from the mouse gastric fundus.	Eglantina Idrizaj Rachele Garella Giovanni Castellini Hermine Mohr Natalia S Pellegata Fabio Francini Valdo Ricca Roberta Squecco Maria Caterina Baccari	2018	World Journal of Gastroenterology2018，24，35：	2
	2	Extracorporeal techniques in the treatment of exogenous intoxications显示文摘	Garella S		0，，03：	1
	3	Extracorporeal techniques in the treatment of exogenous intoxications显示文摘	Garella S	1988	Kidney Int1988，33，3：	1
	4	Intensive therapy and hematopoietic stem cell rescue in Lymphoma:summary of the keystone lymphoma workshop显示文摘	Phillips G L Garella A Goldstone S	1995	Bone Marrow Transpl1995，15，：	1
	5	Intensive therapy and hemtopoietic stem cell rescue in lymphoma:summary of the keystone lymphoma workshop显示文摘	Philips GL Garella A Goldstone S	1995	Bone Marrow Transpl1995，15，：	1
	6	Extracorporeal techniques in the treatment of exogenous intoxications显示文摘	Garella S	1998	Kidney Int1998，33，33：	1
	7	Intensive therapy and hemtopoietic stem cell rescue in lymphoma : summary of the keystone lymphoma workshop 显示文摘	Philips GL Garella A Goldstone S	1995	Bone Marrow Transpl1995，15，：	1
	8	Extracorporeal techniques in the treatment of exogenousintoxications显示文摘	Garella S	1988	Kidney lnt1988，33，3：	1
	9	Acute interstitial nephritis with glomerulopathy due to nonsteroidal anti-inflammatory agents:a review of its clinical spectrum and effects of steroid therapy显示文摘	Porile JL Bakris GL Garella S	1990	J Clin Pharmacol1990，30，5：	1

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