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| 1 | Endometrial mesenchymal stem cells as a cell based therapy for pelvic organ prolapse显示文摘Pelvic organ prolapse(POP) occurs when the pelvic organs(bladder, bowel or uterus) herniate into the vagina, causing incontinence, voiding, bowel and sexual dysfunction, negatively impacting upon a woman's quality of life. POP affects 25% of all women and results from childbirth injury. For 19% of all women, surgical reconstructive surgery is required for treatment, often augmented with surgical mesh. The surgical treatment fails in up to 30% of cases or results in adverse effects, such as pain and mesh erosion into the bladder, bowel or vagina. Due to these complications the Food and Drug Administration cautioned against the use of vaginal mesh and several major brands have been recently been withdrawn from market. In this review we will discuss new cell-based approaches being developed for the treatment of POP. Several cell types have been investigated in animal models, including a new source of mesenchymal stem/stromal cells(MSC) derived from human endometrium. The unique characteristics of endometrial MSC, methods for their isolation and purification and steps towards their development for good manufacturing practice production will be described. Animal models that could be used to examine the potential for this approach will also be discussed as will a rodent model showing promise in developing an endometrial MSC-based therapy for POP. The development of a preclinical large animal model for assessing tissue engineering constructs for treating POP will also be mentioned. | Stuart J Emmerson Caroline E Gargett | 2016 | World Journal of Stem Cells2016，8，5： | 10 |
| 2 | 澳大利亚奇伦托夫人儿童医院显示文摘伦托夫人儿童医院(Lady Cilento Children’s Hospital)坐落于澳大利亚昆士兰州,于2014年11月全部竣工,共耗资15亿澳元。医院不仅在外观设计上独具匠心,色彩艳丽,同时还配备最先进的诊疗设施.可为儿童患者提供专业医疗服务。医院的设计工作由Conrad Gargett Lyons公司担纲.其设计方案在国际上获得广泛认可,并荣获2014年度“国际设计与健康学院奖”之“未来医疗建筑项目奖”。 | Conrad Gargett Lyons | 2015 | 城市建筑2015，0，19： | 3 |
| 3 | A cancer stem cell origin for human endo- metrial carcinoma 显示文摘 | Hubbard S A Gargett C E | 2010 | Reproduction2010，140，1： | 1 |
| 4 | Identification of surface markers for prospective isolation of human endometrial stromal colony-forming cells显示文摘 | Schwab KE Hutchinson P Gargett CE | | 0，，04： | 1 |
| 5 | Endometrial reconstruction from stem cells显示文摘 | Gargett CE Ye L | 2012 | Fertil Steril2012，98，1： | 1 |
| 6 | Clonogenicity of human endometrial epithelial and stromal cells显示文摘 | Chan RW Schwab KE Gargett CE | 2004 | Biol Reprod2004，70，： | 1 |
| 7 | Clonogenicity of human endometrial epithelial and stromal cells 显示文摘 | Chan R W Schwab K E Gargett C E | 2004 | Biol Reprod2004，70，6： | 1 |
| 8 | Co-expression of two perivascular cell markers isolates mesenchymal stem-like cells from human endometrium显示文摘 | Schwab KE Gargett CE | | 0，，11： | 1 |
| 9 | Identification of label-retaining cel s in mouse endometrium显示文摘 | Chan RW Gargett CE | | 0，，06： | 1 |
| 10 | Identification of label-retaining cells in mouse endometrium 显示文摘 | Chart RW Gargett CE | 2006 | Stem Cells2006，24，6： | 1 |
| 11 | Identification and charactefisation of human endometrial stem/progenitor cells 显示文摘 | Gargett CE | 2006 | N Z J Obstet Gyrmecol2006，46，： | 1 |
| 12 | Co - expression of two perivascular cell markers isolates mesenchymal stem- like ceUs from human endome- trium显示文摘 | Schwab KE Gargett CE | 2007 | Hum Reprod2007，22，： | 1 |
| 13 | Putative stem cell activity of human endometrial epithelial and stromal cells during the menstrual cycle显示文摘 | Schwab KE Chan RW Gargett CE | 2005 | Fertil Stefil2005，84，： | 1 |
| 14 | Identification of label-retaining cells in mouse cndometrium显示文摘 | Chan R W Gargett C E | 2006 | Stem Cells2006，24，6： | 1 |
| 15 | Co-expression of two perivascular cell markers isolates mesenchymal stem-like cells from human endometrium显示文摘 | Schwab KE Gargett CE | 2007 | Hum Reprod2007，22，： | 1 |
| 16 | Identification of label-retaining cells in mouse endometrium 显示文摘 | Chan RW Gargett CE | 2006 | Stem Cells2006，24，6： | 1 |
| 17 | Identification of surface markers for prospective isolation of human endornetrial stromal colony-forming cells显示文摘 | Schwab KE Hutchinson P Gargett CE | 2008 | Hum Reprod2008，23，： | 1 |
| 18 | Stem cells in gynaeeology 显示文摘 | Gargett CE | 2004 | Aust N Z J Obstet Gynaecol2004，44，： | 1 |
| 19 | Public policy and the dependency of nursing home residents in Australia:1968-69 to 2006-07显示文摘 | Susan Gargett | 2010 | Health Policy2010，96，2： | 1 |
| 20 | Identification and characterisation of human endometrial stem/progenitor cells 显示文摘 | Gargett CE | 2006 | Aust N Z J Obstet Gynaecol2006，46，： | 1 |
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