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32篇 您的检索式：作者名="Gartung"

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	题名	作者	年代	出处	被引量
1	Side effects of budesonide in liver cirrhosis due to chronic autoimmune hepatitis: Influence of hepatic metabolism versus portosystemic shunts on a patient complicated with HCC显示文摘AIM: To investigate the systemic availability of budesonide in a patient with Child A drrhosis due to autoimmune hepatitis (AIH) and primary hepatocellular carcinoma, who developed serious side effects.METHODS: Serum levels of budesonide, 6β-OH-budesonide and 16α-OH-prednisolon were measured by HPLC/MS/MS;portosysternic shunt-index (SI) was determined by 99mTc nuclear imaging. All values were compared with a matched control patient without side effects.RESULTS: Serum levels of budesonide were 13-fold increased in the index patient. The ratio between serum levels of the metabolites 6β-OH-budesonide and 16α-OH-prednisolone, respectively, and serum levels of budesonide was diminished (1.0 vs. 4.0 for 6β-OH-budesonide, 4.2 vs.10.7 for 16α-OH-prednisolone). Both patients had portosystemic SI (5.7% and 3.1%) within the range of healthy subjects.CONCLUSION: Serum levels of budesonide vary up to 13-fold in AIH patients with Child A cirrhosis in the absence of relevant portosysternic shunting. Reduced hepatic metabolism, as indicated by reduced metabolite-to-drug ratio, rather than portosystemic shunting may explain systemic side effects of this drug in cirrhosis.	Andreas Geier Carsten Gartung Christoph G.Dietrich Hermann E.Wasmuth Patrick Reinartz Siegfried Matern	2003	World Journal of Gastroenterology2003，9，12：	3
2	Association of polymirphisms of the transforming growth factor-β1 gene with the rate of progression of HCV-induced liver fibrosis显示文摘	Gewaltig J Mangasser-Stephan K Gartung C	2002	Clin Chim Acta2002，316，1：	1
3	Bewertung der dynamischen stabilitatvon erdbauwerken unter eisenbahnverkehr 显示文摘	Hu Y F Gartung E Prtihs H	2003	Geotechnik2003，，：	1
4	Association of polymorphisms of the transforming growth factor - beta 1 gene with the rate of progression of HCV-induced liver fibrosis显示文摘	Gewaltig J Mangasser-Stephan K Gartung C	2002	Clin Chim Acta2002，316，12：	1
5	Association of polymorphisms of the transforming growth faetor-β1 gene with the rate of progression of HCV-induced liver fibrosis显示文摘	Gewaltig J Stephan KM Gartung C at al	2002	Clin Claim Acta2002，316，12：	1
6	Association of polymorphisms of the transforming growth factor beta1 gene with the rate of progression of HCV-induced liver fibrosis显示文摘	Gewaltig J Mangasser-Stephan K Gartung C Biesterfeld S Gressner A M	2002	Clin Chim Acta2002，316，12：	1
7	MRCP and ERCP to detect small ampullary carcinoma显示文摘	Geier A Nguyen HN Gartung C	2000	Lancet2000，356，：	1
8	Association of polymirphisms of the transforming growth factor-β1 gene with the rate of progression of HCV-induced liver fibrosis显示文摘	GEWALTIG J MANGASSER STEPHAN K GARTUNG C	2002	Clin Chim Acta2002，316，1：	1
9	Antiviral therapy in HBeAg positive hepatitis B with normal aminotransferase levels显示文摘	Geier A Dietrich CG Gartung C	2003	Hepatology2003，37，3：	1
10	Association of polymorphisms of the transforming growth factor-β1 gene with the rate of progression of HCV-induced liver fibrosis显示文摘	Jan Gewaltig Kerstin Mangasser-Stephan Carsten Gartung Stefan Biesterfeld Axel M Gressner	2002	Clinica Chimica Acta2002，，1：	1
11	Infrared canopy temperature of early-ripening peach trees under postharvest deficit irrigation显示文摘	Wang D Gartung J	2010	Agricultural Water Management2010，97，11：	1
12	Association of polymorphisms of the transforming growth factor-β1 gene with the rate of progression of HCV-induced liver fibrosis 显示文摘	Gewaltig J Stephan K M Gartung C	2002	Clin Chim Acta2002，316，12：	1
13	MRCP and ERCP to Detect Small Ampullary Carcinoma显示文摘	Geier A Nguyen HN Gartung C	2000	Lancet2000，356，6：	1
14	Down regulation of expression and function of the rat liver Na+/bile acid cotransporter in extrahepatic cholestasis 显示文摘	Gartung C Rahman MA	1996	Gastroenterology1996，110，：	1
15	Association of polymorphisms of the transforming growth factor - beta1 gene with the rate of progression of HCV - induced liver fibrosis显示文摘	Gewaltig J Mangasser - Stephan K Gartung C	2002	Clin Chim Acta2002，316，：	1
16	Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis显示文摘	Andreas Geier Christoph G. Dietrich Sebastian Voigt Suk-Kyum Kim Thomas Gerloff Gerd A. Kullak-Ublick Johann Lorenzen Siegfried Matern Carsten Gartung	2003	Hepatology2003，，2：	1
17	Down-regulation of expression and function of the rat liver Na^+/bile acid cotransporter in extrahepatic cholestasis显示文摘	Gartung C Ananthanarayanan M Rahman M A	1996	Gastroenterology1996，110，：	1
18	Association of polymorphisms of the transforming growth factor-betal gene with the rate of progression of HCV-induced liver fibrosis显示文摘	Gewaltig J Mangasser-Stephan K Gartung C	2002	Clin Chim Acta2002，316，：	1
19	Association of polymorphisms of the transforming growth factor-betal gene with the rate of progression of HCV-induced liver fibrosis 显示文摘	Gewahig J Mangasser-Stephan K Gartung C	2002	Clin Chim Aeta2002，316，12：	1
20	Downregulation of expression and function of the rat liver Na+/bile acid cotransporter in extrahepatic cholestasis 显示文摘	Gartung C Ananthanarayanan M Rahman MA	1996	Gastroenterology1996，110，1：	1

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