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| 1 | The Tryptophan Hydroxylase Inhibitor LX1031 Shows Clinical Benefit in Patients With Nonconstipating Irritable Bowel Syndrome显示文摘 | Philip M. Brown Douglas A. Drossman Alastair J.J. Wood Gary A. Cline Kenny S. Frazier Jessica I. Jackson Johanna Bronner Joel Freiman Brian Zambrowicz Arthur Sands Michael D. Gershon | 2011 | Gastroenterology2011,,2: | 2 |
| 2 | Clinical outcomes of single versus staged hybrid repair for thoracoabdominal aortic aneurysm显示文摘 | Ludovic Canaud Alan Karthikesalingam Dan Jackson Lynne Cresswell Michael Cliff S. Sheraz Markar Gary Maytham Steven Black Matt Thompson | 2013 | Journal of Vascular Surgery2013,,: | 1 |
| 3 | Cadmium and Prostate Cancer: A Critical Epidemiologic Analysis显示文摘 | Abe E. Sahmoun L. Douglas Case Sharon A. Jackson Gary G. Schwartz | 2005 | Cancer Investigation2005,,: | 1 |
| 4 | Rees,Zbigniew Lewandowski,Growing reproducible biofilms with respect to structure and viable cell counts显示文摘 | Gary Jackson Haluk Beyenal Wayne M | 2001 | Journal of Microbiological Methods2001,47,: | 1 |
| 5 | Assimilation of surface soil moisture to estimate profile soil water content显示文摘 | Gary C Heathman Patrick J Starks Lajpat R Ahuja Thomas J Jackson | 2003 | Journal of Hydrology2003,,1: | 1 |
| 6 | Survival and Growth of Clostridium perfringens in Commercial No-Nitrate-or-Nitrite-Added (Natural and Organic) Frankfurters, Hams, and Bacon显示文摘 | Jackson Armitra L Sullivan Gary A Kulchaiyawat Charlwit Sebranek Joseph G Dickson James S | 2011 | Journal of Food Protection2011,,3: | 1 |
| 7 | Prior Lung Disease and Risk of Lung Cancer in a Large Prospective Study显示文摘 | Alyson J. Littman Mark D. Thornquist Emily White Lisa A. Jackson Gary E. Goodman Thomas L. Vaughan | 2004 | Cancer Causes and Control2004,,8: | 1 |
| 8 | Higher Child-Reported Internalizing and Parent-Reported Externalizing Behaviors were Associated with Decreased Quality of Life among Pediatric Cardiac Patients Independent of Diagnosis:A Cross-Sectional Mixed-Methods Assessment显示文摘Background:Pediatric cardiology patients often experience decreased quality of life(QoL)and higher rates of mental illness,particularly with severe disease,but the relationship between them and comparisons across diagnostic groups are limited.This mixed-methods cross-sectional study assessed the association between QoL anxiety and behavior problems among children with structural heart disease,arrhythmia,or other cardiac diagnoses.Methods:Children(6–14 years,n=76,50%female)and their parents completed measures of QoL(PedsQL),behavior(BASC-2,subset of 19 children)and anxiety(MASC-2,children 8+years).Pearson correlations/regression models examined associations between QoL,behavior and anxiety,controlling for age,sex,diagnosis and condition severity.Student t-tests compared results to published normative values.Semi-structured interviews(15 children,13 parents)examined self-and parent-reported perceptions of the patient’s emotional health.Results:Child reported social QoL(95%CI difference:−11.0,−2.1),emotional well-being(95%CI difference:−12.5,−3.8)and adjustment skills(95%CI difference:−13.9,−3.0)were significantly below published norms(p<0.05).Neither age,sex,nor diagnosis were significantly related to questionnaire responses.Compared to children with mild conditions,child and parent-reported QoL was significantly lower in children with complex conditions(np2≥0.14,p<0.05).Lower QoL was strongly associated with more internalizing problems based on both child(r=−0.78,p<0.001)and parent(r=−0.67,p<0.001)reports.Interview responses suggested emotional distress was attributed to“normal”child problems rather than the child’s cardiac problem.Conclusion:Children with complex cardiac conditions,regardless of diagnosis,had diminished QoL.Using the PedsQL in clinical settings may help identify pediatric cardiology patients experiencing emotional distress(i.e.,anxiety and depression). | Jacqueline S.Lee Angelica Blais Julia Jackson Bhavika J.Patel Lillian Lai Gary Goldfield Renee Sananes Patricia E.Longmuir | 2021 | Congenital Heart Disease2021,16,3: | 0 |
| 9 | Longitudinal monitoring for the emergence of epidermal growth factor C797S resistance mutations in non-small cell lung cancer using blood-based droplet digital PCR显示文摘Validation of assays for the C797S mutation as a biomarker for osimertinib resistance is promising in guiding treatment decision-making for multidrug resistant non-small cell lung cancer. A newly developed droplet digital PCR (ddPCR) assay was used to retrospectively evaluate the emergence of the C797S mutation in six remnant plasma samples in this case report. It was found that the detected emergence of C797S clearly correlated with clinical signs of treatment resistance. Had these data been available to aid treatment selection in real time, there would have been hope for recaptured disease response and control instead of treatment cessation. The results of this study show that highly sensitive ddPCR methods can be used for the monitoring of emergent epidermal growth factor somatic variant mutations in circulation. | Mark Bowling Hyder Arastu Victoria Edwards Leisa Jackson Scott Thurston Jordan Reese Hestia Mellert Gary Pestano Paul Walker | 2019 | Cancer Drug Resistance2019,2,3: | 0 |