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| 1 | Hepatitis C virus and non-Hodgkin's lymphomas:Metaanalysisof epidemiology data and therapy options显示文摘Hepatitis C virus(HCV) is a global health problem affecting a large fraction of the world's population: This virus is able to determine both hepatic and extrahepatic diseases. Mixed cryoglobulinemia, a B-cell 'benign' lymphoproliferative disorders, represents the most closely related as well as the most investigated HCVrelated extrahepatic disorder. Since this virus is able to determine extrahepatic [non-Hodgkin's lymphoma(NHL)] as well as hepatic malignancies(hepatocellular carcinoma), HCV has been included among human cancer viruses. The most common histological types of HCV-associated NHL are the marginal zone, the lymphoplasmacytic and diffuse large cell lymphomas. The role of the HCV in the pathogenesis of the B-cell lymphoproliferative disorders is confirmed also by the responsiveness of the NHL to antiviral therapy. The purpose of this review is to provide an overview of the recent literature and a meta analysis of the epidemiology data, to explain the role of HCV in the development of NHL's lymphoma. Furthermore, the possibility to treat these HCV-related NHL with the antiviral therapy or with other therapeutic options, like chemotherapy, is also discussed. | Gabriele Pozzato Cesare Mazzaro Luigino Dal Maso Endri Mauro Francesca Zorat Giulia Moratelli PietroBulian Diego Serraino Valter Gattei | 2016 | World Journal of Hepatology2016，8，2： | 3 |
| 2 | Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia显示文摘 | Gattei V Bulian P llaria M | 2008 | Blood2008，111，3： | 1 |
| 3 | Expression of the c--kit receptor in human lymphomas is restricted to Hodgkin's disease and GD30+ anaplastic large cell lymphomas 显示文摘 | Pinto A Gloghini A Gattei V | 1994 | Blood1994，83，3： | 1 |
| 4 | Deep Endometriosis: Definition, Pathogenesis, and Clinical Management显示文摘 | Paolo Vercellini Giada Frontino Giuliana Pietropaolo Umberto Gattei Raffaella Daguati Pier Giorgio Crosignani | 2004 | American Association of Gynecologic Laparoscopists2004，，2： | 1 |
| 5 | Bladder endometriosis:getting closer and closer to the unifying metastatic hypothesis显示文摘 | Somigliana E Vercellini P Gattei U | 2007 | Fertil Steril2007，87，6： | 1 |
| 6 | Bladder endometriosis:getting closer and closer to the unifying metastatic hypothesis显示文摘 | Somiqliana E Vercellini P Gattei U | | 0，，06： | 1 |
| 7 | Relevance of CD49d protein expression as overall survival and progressive disease prog-nosticator in chronic lymphocytic leukemia显示文摘 | Gattei V Bulian P Del Principe MI | 2008 | Blood2008，111，2： | 1 |
| 8 | The kinetics of reduction of mi- nimal residual disease impacts on duration of response and survival of patients with acute myeloid leukemia显示文摘 | Buccisano F Manrillo L Gattei V | 2006 | Leukemia2006，20，10： | 1 |
| 9 | Bladder endometriosis : getting closer and closer to the unifying metastatic hypothesis 显示文摘 | Somigliana E Vercellini P Gattei U | 2007 | Fertil Steril2007，87，6： | 1 |
| 10 | The kinetics of reduction of minimal residual disease impacts on duration of response and survival of patients with acute myeloid leukemia显示文摘 | Buccisano F Maurillo L Gattei V | 2006 | Leukemai2006，20，10： | 1 |
| 11 | Expression of the RET receptor tyrosine kinase and GDNFR -alpha in normal and leukemic human hematopoietic cells and stromal cells of the bone marrow microenvironment 显示文摘 | Gattei V Celetti A Cerrato A | 1997 | Blood1997，89，9： | 1 |
| 12 | Bladder endome- triosis : getting closer and closer to the unifying metastatic hy- pothesis显示文摘 | Somigliana E Vercellini P Gattei U | 2007 | Fertil Steril2007，87，6： | 1 |
| 13 | Amadori S:Clinical Significance of ZAP-70 protein expression in B-cdll chronin lymphocytic leukemia显示文摘 | Del Principe MI Del poeta G Buccisano F Maurillo L Venditti A Zucchetto A Marini R Niscola P Irno Consalvo MA Mazzone C Ottaviani L Panetta P Bruno A Bomben R Suppo G Degan M Gattei V de Fabritiis P Cantonetti M Lo Coco F Del Principe D | 2006 | Blood2006，，： | 1 |
| 14 | Bladder endometriosis: getting closer and closer to the unifying metastatic hypothesis 显示文摘 | Somigliana E Vercellini P Gattei U | 2007 | Fertil Steril2007，87，： | 1 |
| 15 | Bladder endometriosis: getting closer and closer to the unifying metastatic hypothesis显示文摘 | Somigliana E Vereellini P Gattei U | 2007 | Fertil Steril2007，87，6： | 1 |
| 16 | Bladder endometrio-sis:getting closer and closer to the unifying metastatic hypothesis显示文摘 | Somigliana E Vercellini P Gattei U | 2007 | Fertil Steril2007，87，6： | 1 |
| 17 | Concomitant chronic lymphocytic leukemia and acute myeloid leukemia:Evidence of simultaneous expansion of two independent Clones显示文摘 | Michele Gottardi Valter Gattei Massimo Degan | 2006 | Leukemia & Lymphoma2006，47，5： | 1 |
| 18 | A new approach for the treatment of CLL using chlorambucil/hydroxychloroquine-loaded anti-CD20 nanoparticles显示文摘为长期的淋巴球的白血病(CLL ) 的治疗的当前的途径极大地为幸存改进了预后,但是一些病人对这些治疗学的政体仍然保持折射。因此除了为所有白血病病人减少治疗学的长期的 sideeffects,对为 difficult-to-treat 白血病盒子的新奇治疗学的策略有迫切需要。由于药的 cytotoxicity,当保存非恶意的房间的生存能力时,主要挑战当前是把治疗学的代理人送到肿瘤的房间。在这研究,我们建议 hydroxychloroquine 和 chlorambucil 的高剂量首先在被装进与 anti-CD20 antibody.We 涂的可被细菌破坏的聚合 nanoparticles 的一条治疗学的途径表明了 nanoparticles 的能力在肿瘤 B 房间指向并且使内在化。而且,这些 nanoparticles 能杀死表示 CD20 的低数量,而且传播的不仅 p53-mutated/deleted 白血病房间从长期的淋巴球的白血病病人孤立的主要房间。这些 nanoparticles 的安全也在健康老鼠被表明,并且他们的治疗学的效果在好攻击的白血病的一个新模型被显示出。这些结果证明包含 hydroxychloroquine 和 chlorambucil 的 anti-CD20 nanoparticles 能在控制好攻击的白血病是有效的并且为为另外的 B 房间混乱的治疗采用这条途径提供一个基本原理。 | Sara Capolla Nelly Mezzaroba Sonia Zorzet Claudio Tripodo Ramiro Mendoza-Maldonado Marilena Granzotto Francesca Vita Ruben Spretz Gustavo Larsen Sandra Noriega Eduardo Mansilla Michele Dal Bo Valter Gattei Gabriele Pozzato Luis Nunez Paolo Macor | 2016 | Nano Research2016，9，2： | 0 |
| 19 | Loss of CDKN1B induces an age-related clonal hematopoietic disorder via Notch2 activity dysregulation显示文摘Dear Editor,The tumor suppressor gene CDKN1B,encoding for the p27^(Kip1)(p27)protein,defines the smallest region of deletion on chromosome 12p13 described in clonal hematopoietic disorders(CHDs)[1].Among them,myelodysplastic syndromes(MDSs)display typical onset in the elderly and an indolent behavior that may evolve in acute myeloid leukemia(AML)[2].Recent evidences support a model of parallel clonal evolution at the stem or progenitor cell level and implicate the need of more preclinical,translational and clinical research to identify better ways to timely target clones that may evolve toward malignancy[3,4]. | Ilenia Segatto Gian Luca Rampioni Vinciguerra Ilenia Pellarin Alessandra Dall’Acqua Stefania Berton Francesca Citron Sara D’Andrea Giorgia Mungo Davide Viotto Lorena Musco Arianna Di Napoli Maria Antonietta Aloe Spiriti Vincenzo Canzonieri Valter Gattei Andrea Vecchione Barbara Belletti Gustavo Baldassarre | 2023 | Cancer Communications2023，43，7： | 0 |
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