|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Heat and mass transfer effects on MHD viscoelastic fluid over a stretching sheet through porous medium in presence of chemical reaction显示文摘An attempt has been made to study the heat and mass transfcr effects in a boundary layer flow through porous medtium of an electrically conducting viscoelastic fluid subject to transverse magnetic field in the presence of heat sourcelsink and chemical reaction.It has been considered the effects of radliation,viscous and Joule dissipations and intemal heat generation/absorption.Closed form solutions for the boundary layer equations of viscoelastic,second-grxle and Walters'B’fluid models are obtained.The method of solution involves similarity transformation.The ransfommed equations of thermal and mass transport are solved by applying Kummer's function.The solutions of temperature field for both prescribed surface temperature(PST)as well as prescribed surface heat flux(PHF)are obtained.It is important to remark that the interaction of magnetic field is found to be counterproductive in enhancing velocity and concentration distibution whereas the presence of chemical reaction as well as porous matrix with moderate values of magnetic parameter reduces the temperature and concentration fields at all points of flow domain. | Manoj Kumar Nayak Gauranga Charan Dash Lambodar Prased Singh | 2016 | Propulsion and Power Research2016，5，1： | 4 |
| 2 | Molecular mechanism of action of major Helicobacter pylori virulence factors显示文摘 | Suman Kumar Dhar Rajesh K. Soni Bimal K. Das Gauranga Mukhopadhyay | 2003 | Molecular and Cellular Biochemistry (-)2003，，1： | 1 |
| 3 | Purification of full-length human Pregnane and Xenobiotic Receptor:polyclonal antibody preparation for immunological characterization显示文摘Pregnane and Xenobiotic Receptor (PXR; or Steroid and Xenobiotic Receptor, SXR), a new member of the nuclear receptor superfamily, is thought to modulate a network of genes that are involved in xenobiotic metabolism and elimination. To further explore the role of PXR in body’s homeostatic mechanisms, we for the first time, report successful prokary- otic expression and purification of full-length PXR and preparation of polyclonal antibody against the whole protein. The full-length cDNA encoding a 434 amino acids protein was sub-cloned into prokaryotic expression vector, pET-30b and transformed into E. coli BL21(DE3) cells for efficient over expression. The inclusion body fraction, containing the expressed recombinant protein, was purified first by solubilizing in sarcosine extraction buffer and then by affinity column chromatography using Ni-NTA His-Bind matrix. The efficacy of anti-PXR antibody was confirmed by immunocytology, Western blot analysis, EMSA and immunohistochemistry. The antibody obtained was capable of detecting human and mouse PXR with high specificity and sensitivity. Immunofluorescence staining of COS-1 cells transfected with human or mouse PXR showed a clear nuclear localization. Results from immunohistochemistry showed that level of PXR in liver sections is immunologically detectable in the nuclei. Similar to exogenously transfected PXR, Western blot analysis of cell extract from HepG2 and COLO320DM cells revealed a major protein band for endogenous PXR having the expected molecular weight of 50 kDa. Relevance of other immunodetectable bands with reference to PXR isoforms and current testimony are evaluated. Advantages of antibody raised against full-length PXR protein for functional characterization of receptor is discussed and its application for clinical purposes is envisaged. | Mallampati SARADHI Biji KRISHNA Gauranga MUKHOPADHYAY Rakesh K TYAGI | 2005 | Cell Research2005，15，10： | 1 |
| 4 | Efficacy of vasopressin, steroid, and epinephrine protocol for in-hospital cardiac arrest resuscitation: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis显示文摘OBJECTIVES To assess the effect of vasopressin,steroid and epinephrine(VSE)combination therapy on return of spontan-eous circulation(ROSC)after in-hospital cardiac arrest(IHCA),and test the conclusiveness of evidence using trial sequential ana-lysis(TSA).METHODS The systematic search included PubMed,EMBASE,Scopus,and Cochrane Central Register of Controlled Trials.Randomized controlled trials(RCTs)that included adult patients with IHCA,with at least one group receiving combined VSE therapy were selected.Data was extracted independently by two reviewers.The main outcome of interest was ROSC.Other out-comes included survival to hospital discharge or survival to 30 and 90 days,with good neurological outcomes.RESULTS We included a total of three RCTs(n=869).Results showed that VSE combination therapy increased ROSC(risk ra-tio=1.41;95%CI:1.25-1.59)as compared to placebo.TSA demonstrated that the existing evidence is conclusive.This was also validated by the alpha-spending adjusted relative risk(1.32[1.16,1.49],P<0.0001).Other outcomes could not be meta-analysed due to differences in timeframe in the included studies.CONCLUSIONS VSE combination therapy administered in cardiopulmonary resuscitation led to improved rates of ROSC.Fu-ture trials of VSE therapy should evaluate survival to hospital discharge,neurological function and long-term survival. | Danish Iltaf Satti Yan Hiu Athena Lee Keith Sai Kit Leung Jeremy Man Ho Hui Thompson Ka Ming Kot Arslan Babar Gauranga Mahalwar Abraham KC Wai Tong Liu Leonardo Roever Gary Tse Jeffrey Shi Kai Chan International Health Informatics Study(IHIS)Network | 2022 | Journal of Geriatric Cardiology2022，19，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员