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| 1 | Synchronous and metachronous neoplasms in gastric cancer patients:A 23-year study显示文摘AIM:To determine the prevalence and characteristics of additional primary malignancies in gastric cancer(GC)patients.METHODS:GC patients(862 total;570 men,292women;mean age 59.8±12.8 years)diagnosed at the Department of Gastroenterology at Pomeranian Medical University over a period of 23 years were included in this retrospective analysis of a prospectively maintained database.Mean follow-up time was 31.3±38.6 mo(range 1-241 mo).The following clinicopathological features of patients with synchronous tumors were compared to those with metachronous tumors:age,sex,symptom duration,family history of cancer,tumor site,stage(early vs advanced),histology,and blood group.GC patients with and without a second tumor were compared in terms of the same clinicopathological features.RESULTS:Of 862 GC patients,58(6.7%)developed a total of 62 multiple primary tumors,of which 39(63%)were metachronous and 23(37%)synchronous.Four(6.9%)of the 58 multiple GC patients developed two or more neoplasms.The predominant tumor type of the secondary neoplasms was colorectal(n=17),followed by lung(n=9),breast(n=8),and prostate(n=7).Age was the only clinicopathological feature that differed between GC patients with synchronous vs metachronous malignancies;GC patients with synchronous neoplasms were older than those with metachronous neoplasms(68.0±10.3 years vs 59.9±11.1years,respectively,P=0.008).Comparisons between patients with and without a second primary cancer revealed that the only statistically significant differences were in age and blood group.The mean age of the patients with multiple GC was higher than that of those without a second primary tumor(63.4±11.4years vs 59.5±13.0 years,respectively,P=0.026).GC patients with a second primary tumor were more commonly blood group O than those without(56.2%vs 31.6%,respectively,P=0.002).CONCLUSION:GC patients may develop other primary cancers;appropriate preoperative and postoperative diagnostic modalities are thus required,particularly if patients are older and blood group O. | Magorzata Lawniczak Alicja Gawin Halina Jaroszewicz-Heigelmann Wiesawa Rogoza-Mateja Joanna Raszeja-Wyszomirska Andrzej Biaek Katarzyna Karpińska-Kaczmarczyk Teresa Starzyńska | 2014 | World Journal of Gastroenterology2014，20，23： | 8 |
| 2 | Preparation of a new Cd(Ⅱ)-imprionted polymer and its application to determination of cadmium(Ⅱ) via flow-injection-flame atomic absorption spectrometry 显示文摘 | Gawin M Konefal J Trzewik B | 2010 | Talanta2010，80，3： | 1 |
| 3 | Cocaine addiction: psychology and neurophy-siology 显示文摘 | | 1991 | Science1991，251，5001： | 1 |
| 4 | Preparation of a new Cd(1-1)-imprinted polymer and its application to determination of cadmium (II) via flow-injection-flame atomic absorption spectrometry 显示文摘 | Gawin M Koncfa J Trzewik B | 2010 | Talanta2010，80，3： | 1 |
| 5 | Modelling of hygrothermal behavior and damage of concrete at temperature with thermo-chemical and mechanical material degradation 显示文摘 | Gawin D Pesavento F Schrefler B A | 2003 | Computer Methods in Applied Mechanics and Engineering2003，192，14： | 1 |
| 6 | Coupled heat, water and gas flow in deformable porous media显示文摘 | Gawin D Baggio P Schrefler B A | 1995 | Int J Numer Meth Fluids1995，20，89： | 1 |
| 7 | Application of a metal ion-imprinted polymer based on salen-Cu complex to flow injection preconcentration and FAAS determination of copper显示文摘 | Walas S Tobiasz A Gawin M | 2008 | Talanta2008，76，1： | 1 |
| 8 | Hygro-thermo-chemo-mechanical modelling of concrete at early ages and beyond: Part II: Shrinkage and creep of concrete显示文摘 | Gawin D Pesavento F Schrefler B A | 2006 | International Journal forNumerical Methods in Engineering2006，67，3： | 1 |
| 9 | Modelling of hygro-thermal behaviour of concrete at high temperature with thermo-chemical and mechanical material degradation显示文摘 | GAWIN D PESAVENTO F SCHREFLER B A | 2003 | Computer Methods in Applied Mechanics and Engineering2003，192，1314： | 1 |
| 10 | Modelling of hygro-thermal behaviour of concrete at high temperature with thermo-chemical and mechanical material degradation显示文摘 | GAWIN D PESAVENTO F SCHREFLER B A | 2003 | Computer Methods in Applied Mechanics Engineering2003，192，： | 1 |
| 11 | Modelling of hygro-thermal behaviour of concrete at high temperature with thermo-chemical and mechanical material degradation 显示文摘 | Gawin D Pesavento F Schrefler B A | 2003 | Computer Methods in Applied Mechanics and Engineering2003，192，： | 1 |
| 12 | Numerical analysis of hygro-thermal behaviour and damage of concrete at high temperature 显示文摘 | ] GAWIN D MAJORANA C E SCHREFLER B A | 1999 | Mechanics of Cohesive-Frictional1999，4，： | 1 |
| 13 | Numericalanalysis of hydro-thermal behaviour and damage ofconcrete at high temperature 显示文摘 | Gawin D Majorana C E Schrefler B A | 1999 | Mechanics ofCohesive-Frictional Materials1999，4，1： | 1 |
| 14 | Effects of substance P and calcitonin gene and related peptide (CGRP) on guinea pig nasal mucosal secretion in vivo显示文摘 | Gawin AZ Baraniuk JN Kaliner MA | 1993 | Acta Otolaryngol1993，113，4： | 1 |
| 15 | Abstinence symptomatology and psychiatric diagnosis in cocaine abusers显示文摘 | Gawin FH Kleber HD | | 0，，： | 1 |
| 16 | Modeling of hydro - thermal behavior of concrete at high temperature with thermo -chemical and mechanical material degradation 显示文摘 | Gawin D Pesavento F Sctwefler B A | 2003 | Computer Methodsin Applied Mechanics and Engineering2003，192，： | 1 |
| 17 | Modeling hygro-thermal performance and strains of cementitious building materials maturing in variable conditions显示文摘 | Gawin D Wyrzykowski M Pesavento F | 2008 | Journal of Building Physics2008，31，4： | 1 |
| 18 | Preparation of a new Cd (II) -imprinted polymer and its application to determination of cadmium( II ) via flow - injection - flame atomic absorption spectrometry 显示文摘 | Gawin M Konefal J Trzewik B | 2010 | Talanta2010，80，3： | 1 |
| 19 | Modelling creep and shrinkage of concrete by means of effective stresses显示文摘 | GAWIN D PESAVENTO F SCHREFLER B A | 2007 | Materials and Structures2007，40，6： | 1 |
| 20 | Modelling of deformations of high strength concrete at elevated temperatures 显示文摘 | Gawin D Pesavento F Schrefler B A | 2004 | Materials and Structures2004，37，4： | 1 |
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