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| 1 | Immediate nipple-areola-sparing mastectomy reconstruction: An update on oncological and reconstruction techniques显示文摘Nipple-sparing mastectomy(NSM) is a safe technique in patients who are candidates for conservation breast surgery. However, there is worry concerning its oncological safety and surgical outcome in terms of postoperative complications. The authors reviewed the literature to evaluate the oncological safety, patient selection, surgical techniques, and also to identify the factors influencing postoperative outcome and complication rates. Patient selection and safety related to NSM are based on oncological and anatomical parameters. Among the main criteria, the oncological aspects include the clinical stage of breast cancer, tumor characteristics and location including small, peripherally located tumors, without multicentricity, or for prophylactic mastectomy. Surgical success depends on coordinated planning with the oncological surgeon andcareful preoperative and intraoperative management. In general, the NSM reconstruction is related to autologous and alloplastic techniques and sometimes include contra-lateral breast surgery. Choice of reconstructive technique following NSM requires accurate consideration of various patient related factors, including: breast volume, degree of ptosis, areola size, clinical factors, and surgeon's experience. In addition, tumor related factors include dimension, location and proximity to the nipple-areola complex. Regardless of the fact that there is no unanimity concerning the appropriate technique, the criteria are determined by the surgeon's experience and the anatomical aspects of the breast. The positive aspects of the technique utilized should include low interference with the oncological treatment, reproducibility, and long-term results. Selected patients can have safe outcomes and therefore this may be a feasible option for early breast cancer management. However, available data demonstrates that NSM can be safely performed for breast cancer treatment in selected cases. Additional studies and longer follow-up are necessary to define consistent selection criteria for NSM. | Alexandre Mendon?a Munhoz Eduardo Montag José Roberto Filassi Rolf Gemperli | 2014 | World Journal of Clinical Oncology2014，5，3： | 15 |
| 2 | Current aspects of therapeutic reduction mammaplasty for immediate early breast cancer management: An update显示文摘Breast-conservation surgery(BCS) is established as a safe surgical treatment for most patients with early breast cancer. Recently, advances in oncoplastic techniques are capable of preserving the breast form and quality of life. Although most BCS defects can be managed with primary closure, the aesthetic outcome may be unpredictable. Among technical options, therapeutic reduction mammaplasty(TRM) remains a useful procedure since the BCS defect can be repaired and the preoperative appearance can be improved, resulting in more proportional breasts. As a consequence of rich breast tissue vascularization, the greater part of reduction techniques have based their planning on preserving the pedicle of the nipple-areola complex after tumor removal. Reliable circulation and improvement of a conical shape to the breast are commonly described in TRM reconstructions. With an immediate approach, the surgical process is smooth since both procedures can be carried out in one operative setting. Additionally,it permits wider excision of the tumor, with a superior mean volume of the specimen and potentially reduces the incidence of margin involvement. Regardless of the fact that there is no consensus concerning the best TRM technique, the criteria is determined by the surgeon's experience, the extent/location of glandular tissue resection and the size of the defect in relation to the size of the remaining breast. The main advantages of the technique utilized should include reproducibility, low interference with the oncological treatment and long-term results. The success of the procedure depends on patient selection, coordinated planning and careful intra-operative management. | Alexandre Mendona Munhoz Eduardo Montag Rolf Gemperli | 2014 | World Journal of Clinical Oncology2014，5，1： | 5 |
| 3 | Mapping malaria trans- mission in West and Central Africa显示文摘 | Gemperli A Sogoba N Fondjo E | 2006 | Trop Med Int Health2006，1，7： | 1 |
| 4 | Enamel matrix derivative: a review of cellular effects in vitro and a model of molecular arrangement and functioning 显示文摘 | Grandin HM Gemperli AC Dard M | 2012 | Tissue engineering part B-reviews2012，18，3： | 1 |
| 5 | Combined tretinoin and glycolic acid treatment improves mouth opening for postbum patients 显示文摘 | Salles A G Gemperli R Toledo P N | 2006 | Aesthetic Plast Surg2006，30，3： | 1 |
| 6 | Reconstruction of the vulva,perineum and perianal region with a myocutaneous flap of the gracilis muscle显示文摘 | Monteiro Junior AA Souen J Gemperli R | 1983 | Rev Hosp Clin Fac Med San Panlo1983，38，3： | 1 |
| 7 | In vitro ch- aracterization of a synthetic calcium phosphate bone graft on periodontal ligament cell and osteoblast behavior and its combination with an enamel matrix derivative 显示文摘 | Miron RJ Bosshardt DD Gemperli AC | 2014 | ClinOral Invest2014，18，2： | 1 |
| 8 | ln vitro char- acterization of a synthetic calcium phosphate bone graft on periodontal ligament cell and osteoblast behavior and its combination with an enamel matrix derivative显示文摘 | Miron RJ Bosshardt DD Gemperli AC | 2014 | Clin Oral Invest2014，18，2： | 1 |
| 9 | Spatial patternsof infant mortality in Mali: the effect of malaria endemicity 显示文摘 | Gemperli A Vounatsou P Kleinschmidt I | 2004 | Am J Epidemiol2004，159，： | 1 |
| 10 | Free radical production by Nd:YAG laser photodisruption显示文摘 | Timberlake GT Gemperli AW Larive CK Warren KA Mainster MA | 1997 | Ophthalmic Surg Laser1997，28，： | 1 |
| 11 | A growing degree-days based time-series analysis for prediction of Schistosoma japonicum transmission in Jiangsu province, China显示文摘 | Yang G J Gemperli A Vounatsou P | 2006 | Am J Trop Med Hyg2006，75，3： | 1 |
| 12 | The mini-clinical e- valuation exercise during medical clerkships: are learning needs and learning goals aligned显示文摘 | Montagne S Rogausch A Gemperli A | 2014 | Med Educ2014，48，10： | 1 |
| 13 | Reconstruction of a postauricular defect using a preauricular flap显示文摘 | De Almeida O M Gemperli R | | 0，，07： | 1 |
| 14 | Aesthetic Refinements in Breast Augmentation with Deep Inferior Epigastric Perforator Flap: A Case Report显示文摘 | Alexandre Mendon?a Munhoz Luis Henrique Ishida Gustavo Gibin Duarte Marcelo Sacramento Cunha Eduardo Montag Gustavo Sturtz Rolf Gemperli Marcus Castro Ferreira | 2003 | Aesthetic Plastic Surgery2003，，2： | 1 |
| 15 | Efficacy of six doses of artemether-lumefantine (Benflumetol) in multidrugresistant Plasmodium falciparum malaraia 显示文摘 | van Vugt M Wilairatana P Gemperli B | 1999 | Am J Trop Med Hyg1999，60，： | 1 |
| 16 | The role of plastic surgery in congenital cutis laxa: a 10-year follow-up 显示文摘 | Nahas FX Sterman S Gemperli R | 1999 | Plast Reconstr Surg1999，104，11： | 1 |
| 17 | Efficacy of six doses of artemether-lumefantrine (benflumetol) in multidrug-resistant Plasmodium falciparum malaria 显示文摘 | Vugt MV Wilairatana P Gemperli B | 1999 | Am J Trop Med Hyg1999，60，6： | 1 |
| 18 | Combined tretinoin and glyeolic acid treatment improves mouth opening for postburn patients 显示文摘 | Salles AG Gemperli R Toledo PN | 2006 | Aesthetic Plast Sarg2006，30，3： | 1 |
| 19 | Enamel matrix derivative: a review of cellular effects in vitro and a model of molecular arrangement and functioning显示文摘 | Grandin HM Gemperli AC Dard M | 2012 | Tissue Eng Part B Rev2012，18，3： | 1 |
| 20 | NQO1-dependent redox cycling of idebenone:effects on cellular redox potential and energy levels显示文摘 | Haefeli RH Erb M Gemperli AC | 2011 | PLoS One2011，6，17： | 1 |
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