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| 1 | Should antibiotics be administered before arthroscopic knee surgery? A systematic review of the literature显示文摘AIM To explore the current evidence surrounding the administration of prophylactic antibiotics for arthroscopic knee surgery. METHODS Databases were searched from inception through May of 2018 for studies examining prophylactic antibiotic use and efficacy in knee arthroscopy. Studies with patient data were further assessed for types of arthroscopic procedures performed,number of patients in the study,use of antibiotics,and outcomes with the intention of performing a pooled analysis. Data pertaining to 'deep tissue infection' or 'septic arthritis' were included in our analysis. Reported data on superficial infection were not included in our data analysis. For the pooled analysis,a relative risk ratio was calculated and χ~2 tests were used to assess for statistical significance between rates of infection amongst the various patient groups. Post hoc power analyses were performed to compute the statistical power obtained from our sample sizes. Number needed to treat analyses were performed for statistically significant differences by dividing 1 by the difference between the infection rates of the antibiotic and no antibiotic groups. An alpha value of 0.05 was used for our analysis. Study heterogeneity was assessed by Cochrane's Q test as well as calculation of the I^2 value.RESULTS A total of 49682 patients who underwent knee ar-throscopy for a diverse set of procedures across 19 studies met inclusion critera for pooled analysis. For those not undergoing graft procedures,there were 27 cases of post-operative septic arthritis in 34487 patients(0.08%) who received prophylactic antibiotics and 16 cases in 10911(0.15%) who received none [risk ratio(RR) = 0.53,95% confidence interval(CI): 0.29-0.99,P = 0.05]. A sub-group analysis in which bony procedures were excluded was performed which found no significant difference in infection rates between patients that received prophylactic antibiotics and patients that did not(P > 0.05). All anterior cruciate ligament reconstruction studies used prophylactic antibiotics,but two studies investigating the effect of soaking the graft in vancomycin in addition to standard intravenous(IV) prophylaxis were combined for analysis. There were 19 cases in 1095 patients(1.74%) who received IV antibioitics alone and no infections in 2034 patients who received IV antibiotics and had a vancomycin soaked graft(RR = 0.01,95%CI: 0.001-0.229,P < 0.01).CONCLUSION Prophylactic antibiotics are effective in preventing septic arthritis following simple knee arthroscopy. In procedures involving graft implantation,graft soaking reduces the rate of infection. | John Carney Nathanael Heckmann Erik N Mayer Ram K Alluri Carleton Thomas Vangsness George F Hatch Ⅲ Alexander E Weber | 2018 | World Journal of Orthopedics2018，9，11： | 2 |
| 2 | Meta-Analysis of Retrograde Signaling in Arabidopsis thaliana Reveals a Core Module of Genes Embedded in Complex Cellular Signaling Networks显示文摘Plastid-to-nucleus 发信号为响应 environmentaland 的细胞的新陈代谢的协作和调整是必要的植物房间的发展暗示。许多运作后退表明小径被描述了被反应的氧种类,光合作用氧化还原作用不平衡, tetrapyrrole 中介,和 othermetabolic 特点要触发的那 arethought。这里,我们基于 transcriptome 和蛋白质相互作用数据报导元分析。比较 outputof 这些小径揭示在 operationalretrograde 发信号上侵犯的六不同来源刺激的公共和怪癖。我们的学习提供新奇卓见进这些小径的相互影响,支持当还未知的存在 ofan 基因的核心反应模块在测试的所有条件下面正在被调整。我们的分析进一步的 highlightsaffiliated 规章的 cis 元素并且分类 abscisic 酸并且作为涉及反应 cascadesfollowing 的第二等的部件的基于植物生长素的发信号一个 plastidial 信号。我们的学习提供结构的全球分析和不同小径 involvedin plastid-to-nucleus 在这建筑群上发信号和一个新看法的接口细胞的通讯 network.Key 词: | Christine GlaiBer Georg Haberer Iris Finkemeier Thomas Pfannschmidt Tatjana Kleine Dario Leister KarI-Josef Dietz Rainer Erich Haiusler Bernhard Grimm Klaus Franz Xaver Mayer | 2014 | Molecular Plant2014，7，7： | 2 |
| 3 | A Cambrian micro-lobopodian and the evolution of arthropod locomotion and reproduction显示文摘The evolutionary success of arthropods, the most abundant and diverse animal group, is mainly based on their segmented body and jointed appendages, features that had evolved most likely already before the Cambrian. The first arthropod-like animals, the lobopodians from the Early Cambrian, were unsclerotized and worm-like, and they had unjointed tubular legs. Here we describe the first three-dimensionally preserved Cambrian lobopodian. The material presented of Orstenotubulus evamuellerae gen. et sp. nov. is the smallest and youngest of a lobopodian known. O. evamuellerae shows strikingly detailed similarities to Recent tardigrades and/or onychophorans in its cellular-structured cuticle and the telescopic spines. It also shows similarities to other, longer known lobopodians, but which are ten times as large as the new form. These similarities include the finely annulated body and legs, which is characteristic also for Recent onychophorans, and paired humps continuing into spines situated dorsally to the leg insertions, a feature lacking in the extant forms. The morphology of O. evamuellerae not only elucidates our knowledge about lobopodians, but also aids in a clearer picture of the early evolution of arthropods. An example is the single ventral gonopore between a limb pair of O. evamuellerae, which indicates that a single gonopore, as developed in onychophorans, tardigrades, pentastomids, myriapods and insects, might represent the plesiomorphic state for Arthropoda, while the paired state in chelicerates and crustaceans was convergently achieved. Concerning life habits, the lateral orientation of the limbs and their anchoring spines of the new lobopodian imply that early arthropods were crawlers rather than walkers. | Andreas Maas Georg Mayer Reinhardt M. Kristensen Dieter Waloszek | 2007 | Chinese Science Bulletin2007，52，24： | 2 |
| 4 | Rigid biological composite materials: Structural examples for biomimetic design显示文摘 | George Mayer Mehmet Sarikaya | 2002 | Experimental Mechanics2002，，4： | 1 |
| 5 | Clinical applications of robotic technology in vascular and endovascular surgery显示文摘 | George A. Antoniou Celia V. Riga Erik K. Mayer Nicholas J.W. Cheshire Colin D. Bicknell | 2011 | Journal of Vascular Surgery2011，，2： | 1 |
| 6 | Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy显示文摘 | George L. Wright B. Mayer Grob Cara Haley Katie Grossman Kathy Newhall Daniel Petrylak John Troyer Alice Konchuba Paul F. Schellhammer Richard Moriarty | 1996 | Urology1996，，2： | 1 |
| 7 | How mole ratio of UF resin affects formaldehyde emission and other properties显示文摘 | GEORGE E MAYERS | 1981 | Forest Products Journal1981，34，5： | 1 |
| 8 | Discovering Your Authentic Leadership显示文摘 | George Bill Sims Peter McLean Andrew N Mayer Diana | | 0，，02： | 1 |
| 9 | Atomic - layer deposition of wear - resistant coatings for microelectromechanical devices 显示文摘 | Mayer T M Elam J W George S M | 2003 | Applied Physics Letters2003，82，： | 1 |
| 10 | Fifteen Million Years of Evolution in the Oryza Genus Shows Extensive Gene Family Expansion显示文摘在在为 O 可得到的整个染色体的序列分析基因家庭。sativa (AA ) , O。glaberrima (AA ) ,和 O。brachyantha (FF ) ,我们为总科与 FF 染色体相比在 AA 染色体观察了大尺寸扩大 F 盒子和 NB 弧,和五个另外的家庭:丁氨二酸朊酶, BTB/POZ 蛋白质(BTB ) , Glutaredoxins,胰岛素淀粉酶禁止者蛋白质,和 Zf-Dof 蛋白质。他们的进化动态被调查理解怎么并且如此的重要尺寸 variationsare 为什么在这些之间观察密切相关的种类。我们证明扩大源于扩大主要由 tandemduplications,并且由基因损失的收缩。为 F 盒子和 NB 弧基因家庭,当扩展 orthologous 基因在更多下面净化选择放松时,基因在所有种类 wereunder 保存了强壮的净化选择。在 F 盒子, NB 弧,和 BTB,扩展的组与表示的小证据在基因被充实,与也检测的保存 groups.We 比较在在扩展的组的积极选择下面的 87 loci。这些结果显示出扩展的组发展的复制 copiesin 的那个大多数在复制以后的中立因为功能的冗余性而是很少的这些基因 werepreserved 追随者 neofunctionalization。因此,在 Oryza 种类之间观察的系特定的扩大被方向性的 selection.Key 词部分驾驶: | Julie Jacquemin Jetty S.S. Ammiraju Georg Haberer Dean D. Billheimer Yeisoo Yu Liana C. Liu Luis F. Rivera Klaus Mayer Mingsheng Chen Rod A. Wing | 2014 | Molecular Plant2014，7，4： | 1 |
| 11 | Cyclic flexure and laminar flow synergistically accelerate mesenchymal stem cell-mediated engineered tissue formation: Implications for engineered heart valve tissues显示文摘 | George C. Engelmayr Virna L. Sales John E. Mayer Michael S. Sacks | 2006 | Biomaterials2006，，36： | 1 |
| 12 | Origin and differentiation of nephridia in the Onychophora provide no support for the Articulata显示文摘 | Georg Mayer | 2006 | Zoomorphology2006，，1： | 1 |
| 13 | Impact of irritable bowel syndrome on patients? lives: development and psychometric documentation of a disease-specific measure for use in clinical trials显示文摘 | George F. Longstreth Roger Bolus Bruce Naliboff Lin Chang Károly R. Kulich Jonas Carlsson Emeran A. Mayer J?rgen Naesdal Ingela K. Wiklund | 2005 | European Journal of Gastroenterology & Hepatology2005，，4： | 1 |
| 14 | Discovering your authentic leadership 显示文摘 | George B Sims P McLean A N Mayer D | 2007 | Harvard business review2007，85，2： | 1 |
| 15 | Atomic-layer deposition of wear-resistant coatings for microelectromechanical devices显示文摘 | Mayer T M Elam J W George S M | 2003 | Applied Physics Letters2003，82，17： | 1 |
| 16 | Spinal Range of Motion: Accuracy and Sources of Error With Inclinometric Measurement显示文摘 | Tom G. Mayer George Kondraske Susan Brady Beals Robert J. Gatchel | 1997 | Spine1997，，17： | 1 |
| 17 | How mole ratio of UF resin affects formaldehyde emission and other properties:A literature critique显示文摘 | GEORGE E MAYERS | 1984 | Forest Products Journal1984，34，5： | 1 |
| 18 | NOD2 Polymorphism Predicts Response to Treatment in Crohn’s Disease—First Steps to a Personalized Therapy显示文摘 | Jan Niess Jochen Klaus Johannes Stephani Carolin Pflüger Nadine Degenkolb Ulrike Spaniol Benjamin Mayer Georgia Lahr Georg Boyen | 2012 | Digestive Diseases and Sciences2012，，4： | 1 |
| 19 | 修炼你的真诚领导力显示文摘安进公司(Amgen)的CEO兼总裁凯文?沙拉尔(Kevin Sharer)曾说:“领导力可以有多种表现形式。你应该坚持真实的自我,而不是去模仿他人。”模仿他人只会使自己变得不真实,而在21世纪,我们需要的是真诚的领导者。真诚的领导者会热切追求自己的目标,坚持自己的价值观,在工作中既用脑也用心。他们懂得与人建立长期且有意义的联系,并严格要求自己,以达到目标。更重要的是,他们能让公司长时期保持优秀的业绩。 | Bill George Peter Sims Andrew N. McLean Diana Mayer | 2007 | 工程经济2007，，7： | 1 |
| 20 | Dawn of complex animal food webs:A new predatory anthozoan(Cnidaria)from Cambrian显示文摘Cnidarians diverged very early in animal evolution;therefore,investigations of the morphology and trophic levels of early fossil cnidarians may provide critical insights into the evolution of metazoans and the origin of modern marine food webs.However,there has been a lack of unambiguous anthozoan cnidarians from Ediacaran assemblages,and undoubted anthozoans from the Cambrian radiation of metazoans are very rare and lacking in ecological evidence.Here,we report a new polypoid cnidarian,Nailiana elegans gen.et sp.nov.,represented by multiple solitary specimens from the early Cambrian Chengjiang biota(-520 Ma)of South China.These specimens show eight unbranched tentacles surrounding a single opening into the gastric cavity,which may have born multiple mesenteries.Thus,N.elegans displays a level of organization similar to that of extant cnidarians.Phylogenetic analyses place N.elegans in the stem lineage of Anthozoa and suggest that the ancestral anthozoan was a soft-bodied,solitary polyp showing octoradial symmetry.Moreover,one specimen of the new polyp preserves evidence of predation on an epifaunal lingulid brachiopod.This case provides the oldest direct evidence of macrophagous predation,the advent of which may have triggered the emergence of complex trophic/ecological relationships in Cambrian marine communities and spurred the explosive radiation of animal body plans. | Qiang Ou Degan Shu Zhifei Zhang Jian Han Heyo Van Iten Meirong Cheng Jie Sun Xiaoyong Yao Rong Wang Georg Mayer | 2022 | The Innovation2022，3，1： | 1 |
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