|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Acute upper gastrointestinal bleeding in patients on long-term oral anticoagulation therapy: Endoscopic findings, clinical management and outcome显示文摘AIM: Acute gastrointestinal bleeding is a severe complication in patients receiving long-term oral anticoagulant therapy.The purpose of this study was to describe the causes and clinical outcome of these patients.METHODS: From January 1999 to October 2003, 111patients with acute upper gastrointestinal bleeding (AUGIB)were hospitalized while on oral anticoagulants. The causes and clinical outcome of these patients were compared with those of 604 patients hospitalized during 2000-2001with AUGIB who were not taking warfarin.RESULTS: The most common cause of bleeding was peptic ulcer in 51 patients (45%) receiving anticoagulants compared to 359/604 (59.4%) patients not receiving warfarin (P<0.05). No identifiable source of bleeding could be found in 33 patients (29.7%) compared to 31/604(5.1%) patients not receiving anticoagulants (P= 0.0001).The majority of patients with concurrent use of non-steroidal anti-inflammatory drugs (NSATDs) (26/35, 74.3%) had a peptic ulcer as a cause of bleeding while 32/76 (40.8%)patients not taking a great dose of NSATDs had a negative upper and lower gastrointestinal endoscopy. Endoscopic hemostasis was applied and no complication was reported.Six patients (5.4%) were operated due to continuing or recurrent hemorrhage, compared to 23/604 (3.8%) patients not receiving anticoagulants. Four patients died, the overall mortality was 3.6% in patients with AUGIB due to anticoagulants, which was not different from that in patients not receiving anticoagulant therapy.CONCLUSION: Patients with AUGIB while on long-term anticoagulant therapy had a clinical outcome, which is not different from that of patients not taking anticoagulants.Early endoscopy is important for the management of these patients and endoscopic hemostasis can be safely applied. | Konstantinos C Thomopoulos Konstantinos P Mimidis George J Theocharis Anthie G Gatopoulou Georgios N Kartalis Vassiliki N Nikolopoulou | 2005 | World Journal of Gastroenterology2005，11，9： | 5 |
| 2 | Reversion of severe hepatopulmonary syndrome in a non cirrhotic patient after corticosteroid treatment for granulomatous hepatitis:A case report and review of the literature显示文摘肝肺症候群(HPS ) 包括肺内的脉管的膨胀的肝疾病,反常肺的煤气的交换和证据被定义为一个临床的三个一组。我们报导在最后年与疲劳,长持续的发烧,体重减轻,门静脉高血压的符号,肝脾大,胆汁郁积和进步 dyspnoea 介绍的 61 岁的男性。临床,实验室和组织检查所见证实了肉芽肿肝炎的诊断。由于肝的导致 granuloma 的门静脉高血压的 HPS 被证明是由提高对比的回响心动描记法证实了的病人的严重血氧不足的原因。在皮质甾治疗以后的 HPS 的回复被新提高对比的回响心动描记法与胆汁郁积的酶的正规化和病人的条件的改进一起证实。这是在有肝的肉芽肿的一个非肝脏硬化症的病人的 HPS 的完全的回复的第一个案例,显示在肝疾病的那肺内分流是功能的现象, HPS 能甚至在象在这种情况中的其他的肝参与被开发。 | Nikolaos Tzovaras Aggelos Stefos Sarah P Georgiadou Nikolaos Gatselis Georgia Papadamou Eirini Rigopoulou Maria Ioannou Ioannis Skoularigis Georgios N Dalekos | 2006 | World Journal of Gastroenterology2006，12，2： | 3 |
| 3 | Heterotopic ossification after the use of recombinant human bone morphogenetic protein-7显示文摘AIM To present the incidence of heterotopic ossification after the use of recombinant human bone morphogenetic protein-7(rhB MP-7) for the treatment of nonunions.METHODS Bone morphogenetic proteins(BMPs) promote bone formation by auto-induction. Recombinant human BMP-7 in combination with bone grafts was used in 84 patients for the treatment of long bone nonunions. All patients were evaluated radiographicaly for the development of heterotopic ossification during the standard assessment for the nonunion healing. In all patients(80.9%) with radiographic signs of heterotopic ossification, a CT scan was performed. Nonunion site palpation and ROM evaluation of the adjacent jointswere also carried out. Factors related to the patient(age, gender), the nonunion(location, size, chronicity, number of previous procedures, infection, surrounding tissues condition) and the surgical procedure(graft and fixation type, amount of rhB MP-7) were correlated with the development of heterotopic ossification and statistical analysis with Pearsons χ~2 test was performed.RESULTS Eighty point nine percent of the nonunions treated with rh BMP-7, healed with no need for further procedures. Heterotopic bone formation occurred in 15 of 84 patients(17.8%) and it was apparent in the routine radiologi-cal evaluation of the nonunion site, in a mean time of 5.5 mo after the rh BMP-7 application(range 3-12). The heterotopic ossification was located at the femur in 8 cases, at the tibia in 6, and at the humerus in οne patient. In 4 patients a palpable mass was present and only in one patient, with a para-articular knee nonunion treated with rhB MP-7, the size of heterotopic ossification affected the knee range of motion. All the patients with heterotopic ossification were male. Statistical analysis proved that patient's gender was the only important factor for the development of heterotopic ossification(P = 0.007). CONCLUSION Heterotopic ossification after the use of rh BMP-7 in nonunions was common but it did not compromise the final clinical outcome in most cases, and affected only male patients. | Marianthi Papanagiotou Zoe H Dailiana Theophilos Karachalios Sokratis Varitimidis Michael Hantes Georgios Dimakopoulos Marianna Vlychou Konstantinos N Malizos | 2017 | World Journal of Orthopedics2017，8，1： | 3 |
| 4 | Role of innovative 3D printing models in the management of hepatobiliary malignancies显示文摘Three-dimensional (3D) printing has recently emerged as a new technique in various liver-related surgical fields. There are currently only a few systematic reviews that summarize the evidence of its impact. In order to construct a systematic literature review of the applications and effects of 3D printing in liver surgery, we searched the PubMed, Embase and ScienceDirect databases for relevant titles, according to the PRISMA statement guidelines. We retrieved 162 titles, of which 32 met the inclusion criteria and are reported. The leading application of 3D printing in liver surgery is for preoperative planning. 3D printing techniques seem to be beneficial for preoperative planning and educational tools, despite their cost and time requirements, but this conclusion must be confirmed by additional randomized controlled trials. | Peter Bangeas Vassilios Tsioukas Vasileios N Papadopoulos Georgios Tsoulfas | 2019 | World Journal of Hepatology2019，11，7： | 2 |
| 5 | Erythrocyte Duffy antigen receptor for chemokines (DARC): diagnostic and therapeutic implications in atherosclerotic cardiovascular disease显示文摘动脉粥样硬化是煽动性的疾病。最后三个十年努力被作了阐明在 atherogenesis 和匾开发的过程被含有的生物化学的小径。Chemokines 是在这个过程的每步的关键调停人。另外,外部血的细胞的部件在动脉粥样硬化患者损害的形成和前进被证明调停人重要。然而,直到最近,数据主要正在集中于白血球和血小板。红血球被考虑 unreceptive 旁观者和有限数据在动脉粥样硬化患者匾的前进和 destabilization 支持了他们的重要性。通过他们为 chemokines (DARC ) 的 Duffy 抗原受体,最近,红血球作为导致 chemokine 的小径的呼吁的管理者被建议了。对每隔一 chemokine 受体 DARC 不一样从 CC 和 CXC chemokine 亚科为几 ligands 拥有高亲密关系。而且, DARC 没被联合到 G 蛋白质或任何另外的细胞内部的发信号系统;因此产生第二条消息不能。红血球 DARC 的准确生物化学的角色尚待坚定。它然而正在质问 DARC 是一个管理者的事实几乎每 CC 和 CXC chemokine ligand 并且因此, DARC 对抗能有效地堵住复杂 pre 煽动性的 chemokine 网络。在现在的评论我们提供在动脉粥样硬化通过 Duffy 抗原系统集中于 erythrocyte-chemokine 相互作用支持红血球的角色的最近的证据的目的。 | Stavros APOSTOLAKIS Georgios K CHALIKIAS Dimitrios N TZIAKAS Stavros KONSTANTINIDES | 2011 | Acta Pharmacologica Sinica2011，32，4： | 2 |
| 6 | Nifekalant in the treatment of life-threatening ventricular tachyarrhythmias显示文摘The aim of the present study is to review the literature and discuss nifekalant's potential use as a first aid drug in an emergency care setting.The PubMed database was used to identify papers,using Keywords nifekalant,MS-551,amiodarone and lidocaine.Nifekalant hydrochloride,formally known as MS-551,is a classⅢ antiarrhythmic agent which acts only by increasing the time course of myocardial repolarization.It was developed and is currently being used only in Japan for the treatment of ventricular tachyarrhythmias.It is a non-selective K+channel blocker without any β-blocking actions.Administration of nifekalant suppressed sustained ventricular tachyarrhythmias in acute coronary syndrome patients,and in cardiac arrest victims as well as during or after cardiac surgery.The major adverse effect of nifekalant is QT interval prolongation and occurrence of torsades de pointes which requires frequent monitoring of the QT interval during nifekalant infusion with adequate dose adjustment.Nifekalant is a possible effective antiarrhythmic agent for refractory ventricular tachyarrhythmias.Further clinical studies are required before nifekalant is routinely used in the emergency care setting. | Ioannis N Pantazopoulos Georgios T Troupis Charalampos N Pantazopoulos Theodoros T Xanthos | 2011 | World Journal of Cardiology2011，3，6： | 2 |
| 7 | Rifaximin for the prevention of spontaneous bacterial peritonitis显示文摘According to a review article by Biecker et al published in a previous issue of World Journal of Gastroenterology in March 2011,intestinal decontamination with norfloxacin remains the mainstay of primary prophylaxis of spontaneous bacterial peritonitis(SBP) at the expense of development of quinolone-resistant bacteria after long-term use.In our research,the administration of a 4-wk regimen with rifaximin 1200 mg/d reduced significantly the ascitic neutrophil count in cirrhotic patients with sterile ascites in line with a significant decrease in plasma endotoxin levels.Our observations concur with recent findings,showing a significantly reduced 5-year probability of SBP in cirrhotic patients taking rifaximin. | Georgios N Kalambokis Athanasia Mouzaki Maria Rodi Epameinondas V Tsianos | 2012 | World Journal of Gastroenterology2012，18，14： | 2 |
| 8 | A two dimensional numerical study of the stick-slip extrusion instability显示文摘 | ELENI T GEORGIOS C G ANDREAS N A | 2007 | J Non-Newton Fluid Mech2007，146，： | 1 |
| 9 | Epitope mapping of cytochrome P4502D6 autoantigen in patients with chronic hepatitis C during α-interferon treatment显示文摘 | Georgios N Dalekos Heiner Wedemeyer Petra Obermayer-Straub Anne Kayser Ayse Barut Hannah Frank Michael P Manns | 1999 | Journal of Hepatology1999，，3： | 1 |
| 10 | Characterization of Outer Membrane Vesicles from Brucella melitensis and Protection Induced in Mice显示文摘 | Eric Daniel Avila-Calderón Ahidé Lopez-Merino Neeta Jain Humberto Peralta Edgar Oliver López-Villegas Nammalwar Sriranganathan Stephen M. Boyle Sharon Witonsky Araceli Contreras-Rodríguez Georgios Pappas | 2011 | Clinical and Developmental Immunology2011，，： | 1 |
| 11 | 3D computer-aided recon- struction of the morphology of teeth with malformations显示文摘 | Kleoniki L Georgios M Nikos N | 1997 | Stud Health Technol Inform1997，43，： | 1 |
| 12 | On low-complexity adaptive wireless push-based data broadcasting显示文摘 | Marianna P Petros N Georgios I P | 2014 | International Journal of Communication Systems2014，27，1： | 1 |
| 13 | A compound real option and AHP methodology for evaluating ICT business alternatives显示文摘 | GEORGIOS N ANGELOU ANASTASIOS | 2009 | Telemetics and informatics2009，，： | 1 |
| 14 | Fertilization program and resin foam soil amendment effects on sod establishment 显示文摘 | PANAYIOTIS A N GEORGIOS T AIMILIA E N | 2005 | Hort Science2005，40，： | 1 |
| 15 | Removal of phosphate species from solution by adsorption onto calcite used as naturall adsorbent显示文摘 | Kostantinos K G Maximos P Georgios N | 2006 | Journal of Hazardous Materials2006，139，3： | 1 |
| 16 | Management of acute pulmonary embolism:a contemporary,risk-tailored approach显示文摘 | GeorGios K ChaliKias Dimitrios N | | 0，，05： | 1 |
| 17 | Cytochrome P450 2A6: a new hepatic autoantigen in patients with chronic hepatitis C virus infection显示文摘 | Georgios N Dalekos Petra Obermayer-Straub Moritz Bartels Takashi Maeda Anne Kayser Sabine Braun Stephanie Loges Eleonore Schmidt M.Eric Gershwin Michael P Manns | 2003 | Journal of Hepatology2003，，5： | 1 |
| 18 | Removal of phosphate species from solution by adsorption onto calcite used as natural adsorbent 显示文摘 | Kostantinos Karageorgiou Maximos Paschalis Georgios N Anastassakis | 2007 | Journal of Hazardous Materials2007，139，3： | 1 |
| 19 | Applying evolutionary computation to the school timetabling problem: the Greek case显示文摘 | Grigorios N B Charalampos N M Georgios P K | 2008 | Computers &Operations Research2008，35，： | 1 |
| 20 | In Vivo Monitoring of Cutaneous Edema using Spectral Imaging in the Visible and Near Infrared 显示文摘 | Georgios N S Michael S Nikiforos K | 2006 | Journal of Investigative Dermatology2006，126，8： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员