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| 1 | Clinical trial perspective for adult and juvenile Huntington's disease using genetically-engineered mesenchymal stem cells显示文摘Progress to date from our group and others indicate that using genetically-engineered mesenchymal stem cells(MSC) to secrete brain-derived neurotrophic factor(BDNF) supports our plan to submit an Investigational New Drug application to the Food and Drug Administration for the future planned Phase 1 safety and tolerability trial of MSC/BDNF in patients with Huntington's disease(HD). There are also potential applications of this approach beyond HD. Our biological delivery system for BDNF sets the precedent for adult stem cell therapy in the brain and could potentially be modified for other neurodegenerative disorders such as amyotrophic lateral sclerosis(ALS), spinocerebellar ataxia(SCA), Alzheimer's disease, and some forms of Parkinson's disease. The MSC/BDNF product could also be considered for studies of regeneration in traumatic brain injury, spinal cord and peripheral nerve injury. This work also provides a platform for our future gene editing studies, since we will again use MSCs to deliver the needed molecules into the central nervous system. | Peter Deng Audrey Torrest Kari Pollock Heather Dahlenburg Geralyn Annett Jan A.Nolta Kyle D.Fink | 2016 | Neural Regeneration Research2016，11，5： | 7 |
| 2 | The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass显示文摘 | Richard G. Moore Amy K. Brown M. Craig Miller Steven Skates W. Jeffrey Allard Thorsten Verch Margaret Steinhoff Geralyn Messerlian Paul DiSilvestro C.O. Granai Robert C. Bast | 2007 | Gynecologic Oncology2007，，2： | 7 |
| 3 | Utility of Tumor Marker HE4 to Predict Depth of Myometrial Invasion in Endometrioid Adenocarcinoma of the Uterus显示文摘 | Richard G. Moore Craig Michael Miller Amy K. Brown Katina Robison Margaret Steinhoff Geralyn Lambert-Messerlian | 2011 | International Journal of Gynecological Cancer2011，，7： | 2 |
| 4 | Serum HE4 levels are less frequently elevated than CA125 in women with benign gynecologic disorders显示文摘 | Richard G. Moore Michael Craig Miller Margaret M. Steinhoff Steven J. Skates Karen H. Lu Geralyn Lambert-Messerlian Robert C. Bast | 2012 | American Journal of Obstetrics and Gynecology2012，，4： | 2 |
| 5 | Down syndrome screening: Suitability of a WHO 5 standardized total hCG assay显示文摘 | Glenn E. Palomaki Geralyn Lambert-Messerlian | 2014 | Clinical Biochemistry2014，，： | 1 |
| 6 | Mesenchymal stem cells for the treatment of neurodegenerative disease显示文摘 | Nanette Joyce Geralyn Annett Louisa Wirthlin Scott Olson Gerhard Bauer Jan A Nolta | 2010 | Regen Med2010，，6： | 1 |
| 7 | Aldose Reductase–Mediated Phosphorylation of p53 Leads to Mitochondrial Dysfunction and Damage in Diabetic Platelets显示文摘 | Wai Ho Tang Jeremiah Stitham Yu Jin Renjing Liu Seung Hee Lee Jing Du Gourg Atteya Scott Gleim Geralyn Spollett Kathleen Martin John Hwa | 2014 | Circulation2014，，15： | 1 |
| 8 | DNA sequencing of ma- ternal plasma to identify Down syndrome and other trisomies in multiple gestations 显示文摘 | Canick JA Kloza EM Geralyn M | 2012 | Prenat Diagn2012，32，8： | 1 |
| 9 | Comparison of bacteria from deep subsurface sediment and adjacent groundwater显示文摘 | Terry C. Hazen Luis Jiménez Geralyne López de Victoria Carl B. Fliermans | 1991 | Microbial Ecology1991，，1： | 1 |
| 10 | 警惕性-护理的要素显示文摘护理及其它卫生保健职业在其实践过程中基本的要求是照护,专业的警惕性是护理中照护的要素。本文运用历史学和理论学为基础结合专业的警惕性,探讨它的构成要素。介绍了护理诊断的两种形式(中心和监视诊断)。中心诊断是指护士对指定计划完成和实施措施的评估,北美护理诊断学会批准了这种类型的诊断。监视诊断是护士评估预期的患者的风险,为突发事件做准备。整体而言,职业和术语研究者要扩大护理诊断术语使其标准化,以利于护士对患者安全的警惕性进行有效的沟通和实践。 | Geralyn Meyer | 2006 | 护理实践与研究2006，3，3： | 1 |
| 11 | The Connexin43 C- Terminal region mediates neuroprotection during stroke显示文摘 | Michael G John F Geralyn R | 2010 | Neuropathol Exp Neurol2010，69，： | 1 |
| 12 | 基于形成复合物的中性分子LC-ESI-MS-MS方法发展显示文摘对于极性与可带电分子而言,电喷雾离子化(ESI)是一种合适的质谱离子化模式,但由于非极性与中性分子的离子化效率低,一般不能直接采用ESI的离子化模式。为了克服电喷雾离子化的这种限制,已经发展了多种相应的策略,本文介绍的方法便是其中一种。这种方法采用一个小的阴离子与中性分子形成复合物,可以有效提高中性分子的电喷雾离子化能力。 | Geralyn Kocan Daniel Tang Douglas M.Fast Steven M.Michael | 2007 | 生命科学仪器2007，5，5： | 1 |
| 13 | Noninvasive identification of patients with early coronary atherosclerosis by assessment of digital reactive hyperemia显示文摘 | Piero O. Bonetti Geralyn M. Pumper Stuart T. Higano David R. Holmes Jeffrey T. Kuvin Amir Lerman | 2004 | Journal of the American College of Cardiology2004，，： | 1 |
| 14 | A Classroom Investigation of the Growth of Metacognitive Awareness in Kindergarten Children Through the Writing Process显示文摘 | Geralyn M. Jacobs | 2004 | Early Childhood Education Journal2004，，1： | 1 |
| 15 | Second - trimester leverls of maternal serum human chorianic gonadotropin and inhibin a as predictors of preeclampsia in the third trimester of pregnancy 显示文摘 | Geralyn M Helayne M Felice P | 2000 | J Soc Gynecol Invest2000，7，2： | 1 |
| 16 | Placenta growth factor levels in second-trimester mateernal serum in Down syndrome pregnancy and in the prediction of preeclampsia显示文摘 | Geralyn M Messerlian L Jacob A | 2004 | Prenat Diagn2004，24，11： | 1 |
| 17 | Analysis of follicular fluid hormone concentrations and granulosa cell mRNA levels for the inhibin-activin-follistatin system: relation to oocyte and embryo characteristics显示文摘 | Toshihiro F Geralyn L M Yisrael S | 2000 | Fertility and Sterility2000，72，2： | 1 |
| 18 | Inhibin B response to EFORT is associated with the outcome of oocyte retrieval in the subsequent in vitro fertilization cycle 显示文摘 | Artur D Geralyn L M Vicente M L | 2000 | Fertility and Sterility2000，74，6： | 1 |
| 19 | The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass显示文摘 | Richard G. Moore Amy K. Brown M. Craig Miller Steven Skates W. Jeffrey Allard Thorsten Verch Margaret Steinhoff Geralyn Messerlian Paul DiSilvestro C.O. Granai Robert C. Bast | 2007 | Gynecologic Oncology2007，，2： | 1 |
| 20 | Second - trimester leverls of maternal serum human chorionic gonadotropin and inhibin a as predictors of preeclampsia in the third trimester of pregnancy 显示文摘 | Geralyn M Helayne M Felice P | 2000 | J Sac Gynecol Invest2000，7，3： | 1 |
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