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| 1 | Effect of rifaximin on gut microbiota composition in advanced liver disease and its complications显示文摘Liver cirrhosis is a paradigm of intestinal dysbiosis. The qualitative and quantitative derangement of intestinal microbial community reported in cirrhotic patients seems to be strictly related with the impairment of liver function. A kind of gut microbial 'fingerprint',characterized by the reduced ratio of 'good' to 'potentially pathogenic' bacteria has recently been outlined,and is associated with the increase in Model for End-Stage Liver Disease and Child Pugh scores. Moreover,in patients presenting with cirrhosis complications such as spontaneous bacterial peritonitis(SBP),hepatic encephalopathy(HE),and,portal hypertension intestinal microbiota modifications or the isolation of bacteria deriving from the gut are commonly reported. Rifaximin is a non-absorbable antibiotic used in the management of several gastrointestinal diseases. Beyond bactericidal/bacteriostatic,immune-modulating and anti-inflammatory activity,a little is known about its interaction with gut microbial environment. Rifaximin has been demonstrated to exert beneficial effects on cognitive function in patients with HE,and also to prevent the development of SBP,to reduce endotoxemia and to improve hemodynamics in cirrhotics. These results are linked to a shift in gut microbes functionality,triggering the production of favorable metabolites. The low incidence of drug-related adverse events due to the small amount of circulating drug makes rifaximin a relatively safe antibiotic for the modulation of gut microbiota in advanced liver disease. | Francesca Romana Ponziani Viviana Gerardi Silvia Pecere Francesca D'Aversa Loris Lopetuso Maria Assunta Zocco Maurizio Pompili | 2015 | World Journal of Gastroenterology2015，21，43： | 16 |
| 2 | Role of Helicobacter pylori infection on nutrition and metabolism显示文摘Helicobacter pylori(H. pylori) is a gram-negative pathogen that is widespread all over the world, infecting more than 50% of the world's population. It is etiologically associated with non-atrophic and atrophic gastritis, peptic ulcer and shows a deep association with primary gastric B-cell lymphoma and gastric adenocarcinoma. Recently, the medical research focused on the modification of the gastric environment induced by H. pylori infection, possibly affecting the absorption of nutrients and drugs as well as the production of hormones strongly implicated in the regulation of appetite and growth. Interestingly, the absorption of iron and vitamin B12 is impaired by H. pylori infection, while infected subjects have lower basal and fasting serum levels of ghrelin and higher concentration of leptin compared to controls. Since leptin is an anorexigenic hormone, and ghrelin stimulates powerfully the release of growth hormone in humans, H. pylori infection may finally induce growth retardation if acquired very early in the childhood and in malnourished children. This review is focused on the nutritional effects of H. pylori infection, such as the reduced bioavailability or the malabsorbption of essential nutrients, and of gastrointestinal hormones, as well as on the relationship between H. pylori and the metabolic syndrome. | Francesco Franceschi Tortora Annalisa Di Rienzo Teresa D'Angelo Giovanna Gianluca Ianiro Scaldaferri Franco Gerardi Viviana Tesori Valentina Lopetuso Loris Riccardo Gasbarrini Antonio | 2014 | World Journal of Gastroenterology2014，20，36： | 11 |
| 3 | Effect of PVD films wet micro-blasting by various AI203 grain sizes on the wear behaviour of coated tools 显示文摘 | Bouzakis K D Bouzakis E Skordaris G Makrimallakis S Tsouknidas A Katirtzoglou G Gerardis S | 2011 | Surface and Coatings Technology2011，205，2： | 1 |
| 4 | Application of tris(2, 2'-bipyridine)ruthenium(Ⅲ) as a chemiluminescent reagent显示文摘 | GERARDI R D BARNETT N W LEWIS S W | 1999 | Anal Chim Acta1999，，378： | 1 |
| 5 | Aggregation of expert opinions显示文摘 | Gerardi D McLeanb R Postlewaite A | | 0，，02： | 1 |
| 6 | Ambient and elevated temperature properties of TiN, TiAlN and TiSiN PVD films and their impact on the cutting performance of coated carbide tools 显示文摘 | Bouzakis K D Skordaris G Gerardis S | 2009 | Surface and Coatings Technology2009，204，67： | 1 |
| 7 | Information acquisition in committees显示文摘 | Gerardi D Yariv L | | 0，，02： | 1 |
| 8 | Patient dosimetry measurements in 50 radilolgy department in belgium显示文摘 | Deierckx D Constales K Gerardy N | 2005 | Radiation Protection Dosimetry2005，117，： | 1 |
| 9 | Sustained Effectiveness of Occipital Nerve Stimulation in Drug - Resistant Chronic Cluster Headache 显示文摘 | Magis D Gerardy PY Remacle JM | 2011 | Headache:The Journal of Head and Face Pain2011，51，8： | 1 |
| 10 | Diabetes显示文摘 | T BANDYOPADHYAY D A GERARDI M L METERSKY | 1991 | Res Clin Pract1991，13，： | 1 |
| 11 | Pre-and post-treatment with pirlindole and dehydropirlindole protects cultured brain cells against nitric oxide-induced death 显示文摘 | Gerardy J Mossay D | 2003 | Eur J Pharm2003，466，11： | 1 |
| 12 | Conflict engagement:a new model for nurses显示文摘 | Gerardi D | 2015 | Am J Nurs2015，115，3： | 1 |
| 13 | Sequential equilibria in Bayesian games with communication 显示文摘 | GERARDI D MYERSON R B | 2007 | Games and Economic Behavior2007，，60： | 1 |
| 14 | Diagnostische Wertigkeit von kontrastverst?rktem Ultraschall (CEUS) und kontrastverst?rktem endoskopischen Ultraschall (ECEUS) zur Differenzierung von Pankreasl?sionen: systematisches Review und Meta-Analyse显示文摘 | M. D’Onofrio E. Biagioli C. Gerardi S. Canestrini E. Rulli S. Crosara R. De Robertis I. Floriani | 2014 | Ultraschall in Med2014，，： | 1 |
| 15 | Patient dosimetry measurements in 50 radilolgy department in belgium 显示文摘 | Deierckx D Constales K Gerardy N | 2005 | Radiation Protection Dosimetry2005，117，： | 1 |
| 16 | Information acquisition in com-mittees显示文摘 | GERARDI D YARIV L | 2008 | Games and Economic Behavior2008，62，2： | 1 |
| 17 | Analytical applications of tris (2,2'-bipyridyl)ruthenium( Ⅲ ) as a chemiluminescent reagent显示文摘 | GERARDI R D BARNETT N W LEWIS S W | 1999 | Analytica Chimica Acta1999，378，： | 1 |
| 18 | Deliberative voting显示文摘 | GERARDI D YARIV L | 2007 | Journalof Economic Theory2007，134，1： | 1 |
| 19 | Com-munication and voting with double-sided information显示文摘 | DORASZELSKI U GERARDI D SQUINTANI F | 2003 | Contributions to Theoretical Economics2003，3，1： | 1 |
| 20 | Determination of Glyphosate Mono-Isopropylamine Salt in Process Samples Using Flow Injection Analysis with Tris(2,2'-Bipyridyl)Ruthenium(Ⅱ) Chemiluminescence Detection显示文摘 | Adcock J L Barnett N W Gerardi R D | 2004 | Talanta2004，64，： | 1 |
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